Results 121 to 130 of about 5,642 (225)

Taxonomy of the order Mononegavirales : update 2016 [PDF]

open access: yes, 2016
In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera
Afonso, Claudio L.   +82 more
core   +1 more source

Animal Exposure Model for Mapping Crimean-Congo Hemorrhagic Fever Virus Emergence Risk

open access: yesEmerging Infectious Diseases
To estimate the determinants of spatial variation in Crimean-Congo hemorrhagic fever virus (CCHFV) transmission and to create a risk map as a preventive public health tool, we designed a survey of small domestic ruminants in Andalusia, Spain.
Sara Baz-Flores   +7 more
doaj   +1 more source

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

open access: yesViruses, 2016
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen that causes high morbidity and mortality. Efficacy of vaccines and antivirals to treat human CCHFV infections remains limited and controversial. Research into pathology and underlying
Marko Zivcec   +4 more
doaj   +1 more source

In situ rolling circle amplification detection of Crimean Congo hemorrhagic fever virus (CCHFV) complementary and viral RNA

open access: yesVirology, 2012
Crimean Congo hemorrhagic fever virus (CCHFV) is a human pathogen that causes a severe disease with high fatality rate for which there is currently no specific treatment. Knowledge regarding its replication cycle is also highly limited. In this study we developed an in situ technique for studying the different stages during the replication of CCHFV. By
Andersson, Cecilia   +4 more
openaire   +2 more sources

Prevalence of crimean Congo hemorrhagic fever in Khyber Pakhtunkhwa, Pakistan

open access: yesTravel Medicine and Infectious Disease
Background: CCHFV is well recognized as a major public health threat and its prevalence and epidemiological distribution in Pakistan and specifically in KP province is not well documented.
Asad Zia   +8 more
doaj   +1 more source

Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever

open access: yesScientific Reports, 2019
Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne bunyavirus, can cause a life-threatening hemorrhagic syndrome in humans but not in its animal host.
Sergio E. Rodriguez   +5 more
doaj   +1 more source

Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21

open access: yesNature Communications
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a negative-sense RNA virus spread by Hyalomma genus ticks across Europe, Asia, and Africa. CCHF disease begins as a non-specific febrile illness which may progress into a severe hemorrhagic disease with no
Shanna S. Leventhal   +14 more
doaj   +1 more source

The CD8+T cells response is sufficient for protection with a CCHFV M-segment based DNA vaccine and GP38 enhances vaccine immunogenicity

open access: yesInternational Journal of Infectious Diseases
Introduction: Crimean-Congo hemorrhagic fever virus (CCHFV) is the most widely distributed tick-borne virus of human medical importance, with outbreaks occurring in the Middle East, Asia, Africa, and parts of Western Europe. Our team developed and tested
Dr. Joseph Golden   +6 more
doaj   +1 more source

The cap-snatching SFTSV endonuclease domain is an antiviral target [PDF]

open access: yes, 2020
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%-30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Amarasinghe, Gaya K   +11 more
core   +1 more source

Antibodies Targeting the CCHFV Nucleocapsid Protein Require TRIM21 for Protection

open access: yes
Abstract Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a negative-sense RNA virus spread by Hyalomma genus ticks across Europe, Asia, and Africa. CCHF disease begins as a non-specific febrile illness which may progress into a severe hemorrhagic disease and there are currently no widely approved or highly efficacious interventions available ...
David Hawman   +8 more
openaire   +1 more source

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