Results 101 to 110 of about 3,945 (173)

Inter-laboratory variation of BLACKBOX CCHFV IgM ELISA.

, 2018
Inter-laboratory variation of BLACKBOX CCHFV IgM ELISA.
Christina Deschermeier (207807), Ronald von Possel (5007197), Kurtesh Sherifi (634266), Xhevat Jakupi (508103), Herbert Schmitz (502023), Yang Liu (4829), Barie Halili (5007206), Lindita Berisha (5007200), Anne Rackow (5007203), Stephan Günther (218223), Petra Emmerich (331026), Salih Ahmeti (508104), Angela Mika (152045)   +12 more
core   +1 more source

Liver and spleen pathology and CCHFV distribution visualized by immunohistochemistry in mice euthanized at 5 dpi.

, 2019
Mice displayed similarly severe pathology with abundant CCHFV immunostaining. Livers had widespread, random, and confluent hepatocellular necrosis (see insets) with minimal inflammation.
Gary P. Kobinger (8067335), Stuart T. Nichol (8067341), Anita K. McElroy (8067326), Jessica R. Harmon (5540843), Jessica R. Spengler (8067344), JoAnn D. Coleman-McCray (8067329), Jana M. Ritter (8067323), Sherif R. Zaki (8067338), Éric Bergeron (5663428), Florine E. M. Scholte (8067332), Stephen R. Welch (8067320), Christina F. Spiropoulou (8067347)   +11 more
core   +1 more source

Screening of an FDA-approved drug library for the identification of entry inhibitors of Crimean-Congo haemorrhagic fever virus

reservedLe infezioni da virus delle febbri emorragiche rappresentano una minaccia per la salute pubblica perché sono causate da virus altamente patogeni per i quali non esistono farmaci approvati.
BOBBO, MARGHERITA
core  

Furin effect on CCHFV-WT and-ASKA growth.

, 2015
FD11 and FD11-Fur cells were infected with CCHFV-WT or CCHFV-ASKA (MOI = 0.1). Cell supernatants were collected daily, and RNA S-segment copy numbers and infectious virus titers were measured by qRT-PCR and TCID50 determination, respectively.
Marko Zivcec (191739), Christina F. Spiropoulou (139312), César G. Albariño (139297), Ayan K. Chakrabarti (139299), Stuart T. Nichol (130422), Éric Bergeron (5663428)   +5 more
core   +1 more source

Seromolecular survey and risk factor analysis of Crimean-Congo haemorrhagic fever orthonairovirus in occupationally exposed herdsmen and unexposed febrile patients in Kwara State, Nigeria.

PLoS ONE
Crimean-Congo haemorrhagic fever virus (CCHFV) is a globally significant tick-borne zoonotic pathogen that causes fatal haemorrhagic disease in humans. Despite constituting an ongoing public health threat, limited research exists on the presence of CCHFV
Oluwafemi Babatunde Daodu, Joseph Ojonugwa Shaibu, Rosemary Ajuma Audu, Daniel Oladimeji Oluwayelu   +3 more
doaj   +1 more source

Environmental driven changes in tick life history can explain the variation in CCHFV prevalence in the Iberian Peninsula

Crimean-Congo haemorrhagic fever virus (CCHFV) is an emerging tick-borne zoonotic disease with a wide geographical distribution and high case mortality in humans.
Ruiz-Fons, Francisco, White, Andy; id_orcid, O'Neill, Xander, O’Neill, Xander, Gortázar, Christian, White, Andy   +5 more
core   +1 more source

Crimean-Congo Hemorrhagic Fever Virus among Goats, Southern Bhutan

Emerging Infectious Diseases
We conducted serosurveillance for Crimean-Congo hemorrhagic fever virus (CCHFV) among goats in southern Bhutan. Testing serum samples from 472 goats for CCHFV-specific IgG using an indirect fluorescent antibody test and ELISA, we found CCHFV antibody ...
Sangay Rinchen, Yoshihiro Kaku, Eunsil Park, Puspa Maya Sharma, Dawa Tshering, Tenzinla Tenzin, Aya Matsuu, Akiko Okutani, Ken Maeda, Shigeru Morikawa   +9 more
doaj   +1 more source

CCHFV traffics through early endosomes in a Rab5-dependent manner.

, 2014
(A) SW13 cells were incubated with CCHFV for indicated times. Then, the cells were fixed, permeabilized, and treated with CellMask blue dye (grey) to stain the cytoplasm and nucleus, anti-N antibody (virus, red), and anti-EEA1 antibody (early endosomes ...
Raisa A. Nikitina (631476), Robert A. Davey (95393), Alexander A. Chepurnov (631477), Cengiz Z. Altuntas (447055), Olena Shtanko (631475)   +4 more
core   +1 more source

CCHFV localizes to and redistributes MVBs during infection.

, 2014
(A) SW13 cells were incubated with CCHFV for indicated times. Subsequently, the samples were fixed, permeabilized, and stained with anti-N antibody (red), anti-CD63 antibody (MVBs, green), and CellMask blue dye (grey).
Raisa A. Nikitina (631476), Robert A. Davey (95393), Alexander A. Chepurnov (631477), Cengiz Z. Altuntas (447055), Olena Shtanko (631475)   +4 more
core   +1 more source

Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21

Nature Communications
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a negative-sense RNA virus spread by Hyalomma genus ticks across Europe, Asia, and Africa. CCHF disease begins as a non-specific febrile illness which may progress into a severe hemorrhagic disease with no
Shanna S. Leventhal, Thomas Bisom, Dean Clift, Deepashri Rao, Kimberly Meade-White, Carl Shaia, Justin Murray, Evan A. Mihalakakos, Troy Hinkley, Steven J. Reynolds, Sonja M. Best, Jesse H. Erasmus, Leo C. James, Heinz Feldmann, David W. Hawman   +14 more
doaj   +1 more source