Results 81 to 90 of about 3,609 (205)

Bushmeat Consumption and the Risk of Zoonotic Tick‐Borne Pathogen Infections in Ghana: An Increasing Risk to Public Health

Public Health Challenges, Volume 4, Issue 3, September 2025.
• Consuming bushmeat comes with the risk of zoonotic tick‐borne pathogen infection. • To protect public health, there is a need for regulations on bushmeat handling and sales, frequent surveillance, and increased education. ABSTRACT Consuming bushmeat is a widely accepted tradition in Ghana and other West African countries, where it is a vital source ...
Christopher Nii Laryea Tawiah‐Mensah, Danielle Ladzekpo, Seth Offei Addo   +2 more
wiley   +1 more source

In situ visualization of CCHFV/ZsG infection.

, 2019
(A) No ZsG fluorescence was observed in pre-clinical CCHFV/ZsG-infected animals. A mouse infected with wild-type CCHFV is shown to demonstrate background autofluorescence levels when using the fluorescence detection setup; strong autofluorescence is seen
Gary P. Kobinger (8067335), Stuart T. Nichol (8067341), Anita K. McElroy (8067326), Jessica R. Harmon (5540843), Jessica R. Spengler (8067344), JoAnn D. Coleman-McCray (8067329), Jana M. Ritter (8067323), Sherif R. Zaki (8067338), Éric Bergeron (5663428), Florine E. M. Scholte (8067332), Stephen R. Welch (8067320), Christina F. Spiropoulou (8067347)   +11 more
core   +1 more source

Mice lacking TNFA-R signaling are partially protected against CCHFV.

, 2022
A. WT (C57BL/6), IL-1R KO and IL-6 KO mice (n = 5 per group) were infected with CCHFV and survival and weight loss were monitored as above. Mice were treated with MAb-5A3 24h after infection to block IFN-I. Significance in time to death was determined by
Collin J. Fitzpatrick (4442518), Christopher P. Stefan (6083399), Curtis R. Cline (12568445), Candace D. Blancett (6083393), Charles J. Shoemaker (7435310), Joseph W. Golden (7435316), Jun Liu (42548), Aura R. Garrison (7435313), Jeffrey M. Smith (239771), Brian D. Carey (6092747), Sharon P. Daye (6034061), Xiankun Zeng (623049)   +11 more
core   +1 more source

Harnessing the Potential of mRNA Vaccines Against Infectious Diseases

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
RNA vaccines are promising because of their flexible design, strong immunogenicity, safety and rapid development. Recent advances have enabled mRNA vaccines to target various pathogens, including viruses such as influenza and HIV, bacteria such as Mycobacteria and Pseudomonas aeruginosa, and parasites such as those causing malaria.
Nouran Rezk, Siobhán McClean
wiley   +1 more source

Histologic, IHC, and ISH findings in the testes of CCHFV-infected cynomolgus macaques.

, 2019
A). Hematoxylin and eosin staining of an animal with a normal appearing testis and no evidence of CCHFV infection. Arrow, seminiferous tubules. B). Hematoxylin and eosin staining of an animal with inflammation of the testis.
Collin J. Fitzpatrick (4442518), Jeffrey W. Koehler (7435331), Justine Zelko (7435328), Olivier Flusin (3636397), Christopher W. Schellhase (6034055), Kayla M. Coffin (7435334), Adrienne Kimmel (5435786), Darci R. Smith (7435307), Franco Rossi (7435325), Joshua Shamblin (399489), Randal J. Schoepp (7435343), Connie S. Schmaljohn (7435346), Charles J. Shoemaker (7435310), Keersten M. Ricks (7435337), Aura R. Garrison (7435313), Joseph W. Golden (7435316), Jun Liu (42548), William Pratt (7435322), Xiankun Zeng (623049), Matt A. Voorhees (7435340)   +19 more
core   +1 more source

Epidemiologic Survey of Crimean-Congo Hemorrhagic Fever Virus in Suids, Spain

Emerging Infectious Diseases
We conducted a cross-sectional study in wild boar and extensively managed Iberian pig populations in a hotspot area of Crimean-Congo hemorrhagic fever virus (CCHFV) in Spain. We tested for antibodies against CCHFV by using 2 ELISAs in parallel.
Mario Frías, Kerstin Fischer, Sabrina Castro-Scholten, Caroline Bost, David Cano-Terriza, Maria Ángeles Risalde, Pelayo Acevedo, Saúl Jiménez-Ruiz, Balal Sadeghi, Martin H. Groschup, Javier Caballero-Gómez, Ignacio García-Bocanegra   +11 more
doaj   +1 more source

Lymphopenia: An early indicator of Crimean‐Congo haemorrhagic fever

Tropical Medicine &International Health, Volume 30, Issue 8, Page 831-837, August 2025.
Abstract Objectives Crimean‐Congo haemorrhagic fever is a lethal tick‐borne disease characterised by initially nonspecific symptoms. While thrombocytopenia and leucopenia are established diagnostic markers, there is a need for earlier indicators. This study evaluates lymphopenia as a marker for Crimean‐Congo haemorrhagic fever.
Hatice Bozkurt Yavuz, Hüseyin Haydar Kutlu   +1 more
wiley   +1 more source

CCHFV modulates members of the Bcl-2 family of genes.

, 2013
Expression levels of (A) BAX, (B) Bcl-xL and (C) HRK genes were quantified by real time qRT-PCR, using mean ± sd of two independent experiments performed in duplicate.
Guy Vernet (174407), Gláucia Paranhos-Baccalà (174398), Raquel Rodrigues (221129), Christophe N. Peyrefitte (335829)   +3 more
core   +1 more source

Genetic tracking of Crimean-Congo haemorrhagic orthonairovirus in Hyalomma population infesting cattle in Nigeria.

PLoS ONE
Crimean-Congo haemorrhagic fever virus (CCHFV), a Biosafety level 4 pathogen transmitted by ticks, causes severe haemorrhagic diseases in humans but remains clinically silent in animals. Over the past forty years, Nigeria lacks comprehensive genetic data
Oluwafemi Babatunde Daodu, Joseph Ojonugwa Shaibu, Rosemary Ajuma Audu, Daniel Oladimeji Oluwayelu   +3 more
doaj   +1 more source

Sufficient reproduction numbers to prevent recurrent epidemics

Methods in Ecology and Evolution, Volume 16, Issue 6, Page 1186-1200, June 2025.
Abstract Current practice in the design and evaluation of control measures in disease ecology and epidemiology, including vaccination, is largely based on reproduction numbers (RNs), which represent prognostic indices of long‐term disease transmission, both in naïve populations (basic RN) and in the presence of prior exposure or infection containment ...
Lorenzo Mari, Cristiano Trevisin, Andrea Rinaldo, Marino Gatto   +3 more
wiley   +1 more source