Results 71 to 80 of about 3,945 (173)

Sero-epidemiological survey of Crimean-Congo hemorrhagic fever virus in Tunisia

open access: yesParasite, 2016
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease associated with a high case fatality rate and transmitted mainly by Hyalomma marginatum. The geographical distribution of H. marginatum covers most of the Western Mediterranean basin.
Wasfi Fares   +11 more
doaj   +1 more source

Histologic, IHC, and ISH findings in the testes of CCHFV-infected cynomolgus macaques.

open access: yes, 2019
A). Hematoxylin and eosin staining of an animal with a normal appearing testis and no evidence of CCHFV infection. Arrow, seminiferous tubules. B). Hematoxylin and eosin staining of an animal with inflammation of the testis.
Collin J. Fitzpatrick (4442518)   +19 more
core   +1 more source

Model schematic of CCHFV transmission.

open access: yes, 2022
We modelled CCHFV viral transmission between livestock, and from livestock to humans. In panel A, livestock were stratified in five yearly age-groups. Animals are born into the model at a rate proportional to mortality to maintain equilibrium. A fraction
Andrea Apolloni (793302)   +6 more
core   +1 more source

Transboundary Animal Diseases and Human Migration: A One Health Perspective on the Balkan Route

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Transboundary animal diseases (TADs), including zoonoses, can be introduced in non‐endemic areas through animal trade and uncontrolled movements during times of conflict and migration. Sheep and goat pox (SGPX) and peste des petits ruminants (PPRs) were, respectively, reported in Europe in 2018 and 2010.
Eleonora Uber   +6 more
wiley   +1 more source

Widespread circulation of Crimean-Congo haemorrhagic fever virus in ticks, Corsica (France), 2024

open access: yesOne Health
Crimean-Congo Haemorrhagic Fever is a severe tick-borne viral disease with a high fatality rate. This study aimed to advance the understanding of CCHF virus (CCHFV) in terms of geographical spread and genotypic characterization by investigating its ...
Morena Gasparine   +6 more
doaj   +1 more source

In situ visualization of CCHFV/ZsG infection.

open access: yes, 2019
(A) No ZsG fluorescence was observed in pre-clinical CCHFV/ZsG-infected animals. A mouse infected with wild-type CCHFV is shown to demonstrate background autofluorescence levels when using the fluorescence detection setup; strong autofluorescence is seen
Gary P. Kobinger (8067335)   +11 more
core   +1 more source

Mice lacking TNFA-R signaling are partially protected against CCHFV.

open access: yes, 2022
A. WT (C57BL/6), IL-1R KO and IL-6 KO mice (n = 5 per group) were infected with CCHFV and survival and weight loss were monitored as above. Mice were treated with MAb-5A3 24h after infection to block IFN-I. Significance in time to death was determined by
Collin J. Fitzpatrick (4442518)   +11 more
core   +1 more source

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

open access: yesViruses, 2016
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen that causes high morbidity and mortality. Efficacy of vaccines and antivirals to treat human CCHFV infections remains limited and controversial. Research into pathology and underlying
Marko Zivcec   +4 more
doaj   +1 more source

Spatial Heterogeneity of Tick‐Borne Pathogens Outpaces Genetic Structuring in Anatolian Dermacentor reticulatus Populations

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Understanding how vector population structure influences pathogen circulation remains a major challenge in tick‐borne disease ecology, particularly in biogeographically transitional regions. Dermacentor reticulatus, a widespread Palearctic tick species and vector of multiple pathogens, provides a useful system to investigate this relationship in a ...
Ömer Orkun   +7 more
wiley   +1 more source

A Low Containment CCHFV Entry Screening Platform Identifies Compounds with Antiviral Activity against Authentic CCHFV

open access: yes
Backgrounds Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne nairovirus that can cause severe human disease in the endemic areas, and no licensed antiviral is broadly available.
Clarice Borges   +15 more
core   +1 more source

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