Results 91 to 100 of about 5,642 (225)

Bunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidase [PDF]

, 2016
This study was supported by Wellcome Trust Grant 099220/B/12/Z (to R.M.E.) and Grant 094476/Z/10/Z that funded the purchase of the TripleTOF 5600 mass spectrometer at the Biomedical Sciences Research Complex (BSRC) of University of St. Andrews.Bunyamwera
Botting, Catherine Helen, Brennan, Benjamin, Elliott, Richard Michael, Li, Ping, Niglas, Mark, Shi, Xiaohong, Shirran, Sally Lorna, Szemiel, Agnieszka Marta   +7 more
core   +2 more sources

Lymphopenia: An early indicator of Crimean‐Congo haemorrhagic fever

Tropical Medicine &International Health, Volume 30, Issue 8, Page 831-837, August 2025.
Abstract Objectives Crimean‐Congo haemorrhagic fever is a lethal tick‐borne disease characterised by initially nonspecific symptoms. While thrombocytopenia and leucopenia are established diagnostic markers, there is a need for earlier indicators. This study evaluates lymphopenia as a marker for Crimean‐Congo haemorrhagic fever.
Hatice Bozkurt Yavuz, Hüseyin Haydar Kutlu   +1 more
wiley   +1 more source

A replicating RNA vaccine confers protection against Crimean-Congo hemorrhagic fever in cynomolgus macaquesResearch in context

EBioMedicine
Summary: Background: Crimean-Congo hemorrhagic fever is a tick-borne febrile illness with wide geographic distribution. In recent years the geographic range of CCHFV and its tick vector have increased, placing an increasing number of people at risk of ...
David W. Hawman, Shanna Leventhal, Kimberly Meade-White, William Graham, Karen Gaffney, Amit Khandhar, Justin Murray, Jessy Prado-Smith, Carl Shaia, Greg Saturday, Henry Buda, Lenny Moise, Jesse Erasmus, Heinz Feldmann   +13 more
doaj   +1 more source

European survey on laboratory preparedness, response and diagnostic capacity for crimean-congo haemorrhagic fever, 2012 [PDF]

, 2014
Crimean-Congo haemorrhagic fever (CCHF) is an infectious viral disease that has (re-)emerged in the last decade in south-eastern Europe, and there is a risk for further geographical expansion to western Europe.
Aberle, S.W. (Stephan), Alves, M.J. (M. João), Avsic, T. (Tatjana), Bosevska, G. (Golubinka), Bozovic, B. (Bojana), Brooks, T. (Tim), Brown, D.W.G. (D. W G), Capobianchi, M.R. (Maria Rosaria), Ceianu, C.S., Charrel, R. (Remi), Cherpillod, P. (Pascal), Christova, I., Donoso-Mantke, O., Dudman, S.G. (Susanne Gjeruldsen), Esbroeck, M. (M.) van, Fernandez-Garcia, M.D. (Maria Dolores), Franco, L. (Leticia), Golovljova, I., Griskevicius, A. (Algirdas), Jakupi, X. (Xhevat), Klempa, B., Korukluoglu, G., Kurolt, I.-C. (Ivan-Christian), Lundkvist, Å. (Åke), Markotic, A. (Alemka), Muscat, C. (Clive), Negredo, A., Niedrig, M., Pannetier, D. (Delphine), Papa, A. (Anna), Papa, A. (Anna), Platonov, A. (Alexander), Schmidt-Chanasit, J. (Jonas), Schutten, M. (Martin), Storozenko, J. (Jelena), Tenorio, A., Tenorio, A., Wölfel, R. (Roman), Zelena, H. (Hana), Zeller, H. (Hervé)   +39 more
core  

Sufficient reproduction numbers to prevent recurrent epidemics

Methods in Ecology and Evolution, Volume 16, Issue 6, Page 1186-1200, June 2025.
Abstract Current practice in the design and evaluation of control measures in disease ecology and epidemiology, including vaccination, is largely based on reproduction numbers (RNs), which represent prognostic indices of long‐term disease transmission, both in naïve populations (basic RN) and in the presence of prior exposure or infection containment ...
Lorenzo Mari, Cristiano Trevisin, Andrea Rinaldo, Marino Gatto   +3 more
wiley   +1 more source

Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line.

PLoS Neglected Tropical Diseases, 2020
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) and Hazara virus (HAZV) belong to the same viral serotype and family. HAZV has lately been used as a model system and surrogate to CCHFV.
Vanessa Monteil, Cristiano Salata, Sofia Appelberg, Ali Mirazimi   +3 more
doaj   +1 more source

A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses [PDF]

, 2014
To combat emerging coronaviruses, developing safe and efficient platforms to evaluate viral protease activities and the efficacy of protease inhibitors is a high priority.
Agnihothram, Sudhakar, Baker, Susan C, Baric, Ralph S, Deng, Xufang, Larsen, Scott D, Lenschow, Deborah J, Mesecar, Andrew D, Mielech, Anna M, Nichols, Daniel B, St. John, Sarah E, Wilson, Michael W   +10 more
core   +3 more sources

Development of a multiplex assay for antibody detection in serum against pathogens affecting ruminants [PDF]

, 2020
Numerous infectious diseases impacting livestock impose an important economic burden and in some cases also represent a threat to humans and are classified as zoonoses.
Barr, JN, Brun, A, Djadjovski, I, Edwards, TA, Fernández‐Pacheco, P, Hoste, ACR, Jiménez‐Clavero, MÁ, Moreno, S, Rueda, P, Ruiz, T, Sastre, P   +10 more
core   +3 more sources

Tick Species Infesting Livestock in Three Bioclimatic Areas of Senegal: Bioecology, Prevalence of Tick Infestation, Associated Categorical Factors and Crimean‐Congo Haemorrhagic Fever Virus Infection

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Ticks were collected between October 2020 and November 2022, from cattle, goats and sheep in the Sahelian, Sudano‐Sahelian and Sudanian zones, and tested for CCHFV infection. A total of 3632 animals were examined and 35.3% (95% CI: 33.8–36.9) found tick‐infested.
Aliou Khoule, Déthié Ngom, Mouhamet Faye, Ousseynou Sene, Aminata Badji, Elhadji Ndiaye, Gamou Fall, Ibrahima Dia, Mawlouth Diallo, Diawo Diallo   +9 more
wiley   +1 more source

Sero-epidemiological survey of Crimean-Congo hemorrhagic fever virus in Tunisia

Parasite, 2016
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease associated with a high case fatality rate and transmitted mainly by Hyalomma marginatum. The geographical distribution of H. marginatum covers most of the Western Mediterranean basin.
Wasfi Fares, Dowall Stuart, Ghabbari Tayssir, Bosworth Andrew, Chakroun Mohamed, Varghese Anitha, Tiouiri Hanene, Ben Jemaa Mounir, Znazen Abir, Hewson Roger, Zhioua Elyes, Letaief Amel   +11 more
doaj   +1 more source