Results 111 to 120 of about 5,642 (225)

Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe, Maryam Diarra, Mamadou Aliou Barry, Martin Faye, Cheikh Talla, Diogop Camara, Maimouna Mbanne, Pape Mbacke Sembene, Amadou Alpha Sall, Gamou Fall, Oumar Faye, Cheikh Loucoubar, Ousmane Faye, Ines Vigan-Womas, Keersten Michelle Ricks, Jessica Radzio-Basu, Moussa Moise Diagne, Leyi Wang   +17 more
wiley   +1 more source

Genetic tracking of Crimean-Congo haemorrhagic orthonairovirus in Hyalomma population infesting cattle in Nigeria.

PLoS ONE
Crimean-Congo haemorrhagic fever virus (CCHFV), a Biosafety level 4 pathogen transmitted by ticks, causes severe haemorrhagic diseases in humans but remains clinically silent in animals. Over the past forty years, Nigeria lacks comprehensive genetic data
Oluwafemi Babatunde Daodu, Joseph Ojonugwa Shaibu, Rosemary Ajuma Audu, Daniel Oladimeji Oluwayelu   +3 more
doaj   +1 more source

Crimean-Congo Hemorrhagic Fever Virus in Ticks Collected from Cattle, Corsica, France, 2023

Emerging Infectious Diseases
We report the detection of Crimean-Congo hemorrhagic fever virus (CCHFV) in Corsica, France. We identified CCHFV African genotype I in ticks collected from cattle at 2 different sites in southeastern and central-western Corsica, indicating an ...
Paloma Kiwan, Shirley Masse, Geraldine Piorkowski, Nazli Ayhan, Morena Gasparine, Laurence Vial, Remi N. Charrel, Xavier de Lamballerie, Alessandra Falchi   +8 more
doaj   +1 more source

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

mBio, 2019
Crimean-Congo hemorrhagic fever virus (CCHFV) infection can result in a severe hemorrhagic syndrome for which there are no antiviral interventions available to date. Certain RNA viruses, such as CCHFV, encode cysteine proteases of the ovarian tumor (OTU)
Florine E. M. Scholte, Brian L. Hua, Jessica R. Spengler, John V. Dzimianski, JoAnn D. Coleman-McCray, Stephen R. Welch, Laura K. McMullan, Stuart T. Nichol, Scott D. Pegan, Christina F. Spiropoulou, Éric Bergeron   +10 more
doaj   +1 more source

Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20 [PDF]

, 2018
Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently ...
Bieniasz, Paul D., Brennan, Benjamin, Elliott, Richard M., Feng, Junjie, Koudriakova, Elina, Kreher, Felix, Rezelj, Veronica V., Rice, Charles M., Rihn, Suzannah J., Shaw, Andrew E., Shi, Xiaohong, Slack, Gillian S., Tilston-Lunel, Natasha L., Turnbull, Matthew L., Wickenhagen, Arthur, Wilson, Sam J.   +15 more
core   +1 more source

Hyalomma marginatum in Europe: The Past, Current Status, and Future Challenges—A Systematic Review

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Hyalomma marginatum is a prominent tick vector responsible for transmitting various pathogens, including the Crimean–Congo hemorrhagic fever virus (CCHFV), across Europe. This systematic review consolidates findings from 144 publications regarding the geographical distribution of H. marginatum and its associated pathogens.
Seyma S. Celina, Jiří Černý, Zongfu Wu   +2 more
wiley   +1 more source

Seromolecular survey and risk factor analysis of Crimean-Congo haemorrhagic fever orthonairovirus in occupationally exposed herdsmen and unexposed febrile patients in Kwara State, Nigeria.

PLoS ONE
Crimean-Congo haemorrhagic fever virus (CCHFV) is a globally significant tick-borne zoonotic pathogen that causes fatal haemorrhagic disease in humans. Despite constituting an ongoing public health threat, limited research exists on the presence of CCHFV
Oluwafemi Babatunde Daodu, Joseph Ojonugwa Shaibu, Rosemary Ajuma Audu, Daniel Oladimeji Oluwayelu   +3 more
doaj   +1 more source

Small Interfering RNAs Are Highly Effective Inhibitors of Crimean-Congo Hemorrhagic Fever Virus Replication In Vitro

Molecules, 2020
Crimean-Congo hemorrhagic fever virus (CCHFV) is one of the prioritized diseases of the World Health Organization, considering its potential to create a public health emergency and, more importantly, the absence of efficacious drugs and/or vaccines for ...
Fanni Földes, Mónika Madai, Henrietta Papp, Gábor Kemenesi, Brigitta Zana, Lili Geiger, Katalin Gombos, Balázs Somogyi, Ildikó Bock-Marquette, Ferenc Jakab   +9 more
doaj   +1 more source

Comparative structural and functional analysis of Bunyavirus and Arenavirus cap-snatching Endonucleases [PDF]

, 2016
Segmented negative strand RNA viruses of the arena-, bunya- and orthomyxovirus families uniquely carry out viral mRNA transcription by the cap-snatching mechanism.
A Dias, A Perrakis, A Pflug, B Morin, C Klemm, D Duijsings, D Garcin, D Guilligay, E Kowalinski, E Krissinel, E Lecompte, E Thierry, Francesca Coscia, Félix A. Rey, G Sutter, GD Wallat, GN Murshudov, H Hasegawa, H Jin, J Ortin, J Reguera, J Tomassini, JC Clegg, Juan Reguera, M Hass, M Hass, M Lelke, M Zeier, Maria Rosenthal, N Dimasi, N Hengrung, P Gerlach, Piotr Gerlach, R Rosenberg, RM Elliott, RW Compans, S Devignot, S Reich, SJ Plotch, SR Ness, Stephan Günther, Stephanie Gaudon, Stephen Cusack, T Crepin, UB Ericsson, UJ Buchholz, W Kabsch, Y Fernández-García   +47 more
core   +3 more sources

Update in the geographical distribution of the invasive tick Hyalomma marginatum in South of France: first attempts to identify factors favoring its establishment [PDF]

, 2018
Hyalomma marginatum, the main tick vector of Crimean-Congo Hemorrhagic Fever virus (CCHFv) in the Mediterranean Basin, has been reported for several decades in Corsica Island. However, its establishment in continental France is much more recent.
Andary, C., Appelgren, Anaïs, Calloix, Clément, Grosbois, Vladimir, Huber, Karine, Lancelot, Renaud, Stachurski, Frédéric, Vial, Laurence   +7 more
core