Results 71 to 80 of about 4,301 (202)

Non-structural proteins of arthropod-borne bunyaviruses: roles and functions [PDF]

, 2013
Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl, Anne-Lie Blomström, Delhaye, Dunn, Esther Schnettler, Geerts-Dimitriadou, Hampsey, Isabelle Dietrich, Kakach, Lanciotti, Nagata, Saleh Eifan, Storms, Verbruggen, Wijkamp, Yadani, Ye, Zhao   +17 more
core   +3 more sources

Bushmeat Consumption and the Risk of Zoonotic Tick‐Borne Pathogen Infections in Ghana: An Increasing Risk to Public Health

Public Health Challenges, Volume 4, Issue 3, September 2025.
• Consuming bushmeat comes with the risk of zoonotic tick‐borne pathogen infection. • To protect public health, there is a need for regulations on bushmeat handling and sales, frequent surveillance, and increased education. ABSTRACT Consuming bushmeat is a widely accepted tradition in Ghana and other West African countries, where it is a vital source ...
Christopher Nii Laryea Tawiah‐Mensah, Danielle Ladzekpo, Seth Offei Addo   +2 more
wiley   +1 more source

Harnessing the Potential of mRNA Vaccines Against Infectious Diseases

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
RNA vaccines are promising because of their flexible design, strong immunogenicity, safety and rapid development. Recent advances have enabled mRNA vaccines to target various pathogens, including viruses such as influenza and HIV, bacteria such as Mycobacteria and Pseudomonas aeruginosa, and parasites such as those causing malaria.
Nouran Rezk, Siobhán McClean
wiley   +1 more source

Nucleocapsid protein-specific monoclonal antibodies protect mice against Crimean-Congo hemorrhagic fever virus

Nature Communications
Crimean-Congo hemorrhagic fever virus (CCHFV) is a WHO priority pathogen. Antibody-based medical countermeasures offer an important strategy to mitigate severe disease caused by CCHFV.
Aura R. Garrison, Vanessa Moresco, Xiankun Zeng, Curtis R. Cline, Michael D. Ward, Keersten M. Ricks, Scott P. Olschner, Lisa H. Cazares, Elif Karaaslan, Collin J. Fitzpatrick, Éric Bergeron, Scott D. Pegan, Joseph W. Golden   +12 more
doaj   +1 more source

A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses [PDF]

, 2014
To combat emerging coronaviruses, developing safe and efficient platforms to evaluate viral protease activities and the efficacy of protease inhibitors is a high priority.
Agnihothram, Sudhakar, Baker, Susan C, Baric, Ralph S, Deng, Xufang, Larsen, Scott D, Lenschow, Deborah J, Mesecar, Andrew D, Mielech, Anna M, Nichols, Daniel B, St. John, Sarah E, Wilson, Michael W   +10 more
core   +3 more sources

Lymphopenia: An early indicator of Crimean‐Congo haemorrhagic fever

Tropical Medicine &International Health, Volume 30, Issue 8, Page 831-837, August 2025.
Abstract Objectives Crimean‐Congo haemorrhagic fever is a lethal tick‐borne disease characterised by initially nonspecific symptoms. While thrombocytopenia and leucopenia are established diagnostic markers, there is a need for earlier indicators. This study evaluates lymphopenia as a marker for Crimean‐Congo haemorrhagic fever.
Hatice Bozkurt Yavuz, Hüseyin Haydar Kutlu   +1 more
wiley   +1 more source

Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line.

PLoS Neglected Tropical Diseases, 2020
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) and Hazara virus (HAZV) belong to the same viral serotype and family. HAZV has lately been used as a model system and surrogate to CCHFV.
Vanessa Monteil, Cristiano Salata, Sofia Appelberg, Ali Mirazimi   +3 more
doaj   +1 more source

Therapeutic antibodies: current state and future trends--is a paradigm change coming soon? [PDF]

, 2008
Antibody-based therapeutics currently enjoy unprecedented success, growth in research and revenues, and recognition of their potential. It appears that the promise of the "magic bullet" has largely been realized.
Dimitrov, Dimiter S, Marks, James D
core   +1 more source

Sufficient reproduction numbers to prevent recurrent epidemics

Methods in Ecology and Evolution, Volume 16, Issue 6, Page 1186-1200, June 2025.
Abstract Current practice in the design and evaluation of control measures in disease ecology and epidemiology, including vaccination, is largely based on reproduction numbers (RNs), which represent prognostic indices of long‐term disease transmission, both in naïve populations (basic RN) and in the presence of prior exposure or infection containment ...
Lorenzo Mari, Cristiano Trevisin, Andrea Rinaldo, Marino Gatto   +3 more
wiley   +1 more source

Sero-epidemiological survey of Crimean-Congo hemorrhagic fever virus in Tunisia

Parasite, 2016
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease associated with a high case fatality rate and transmitted mainly by Hyalomma marginatum. The geographical distribution of H. marginatum covers most of the Western Mediterranean basin.
Wasfi Fares, Dowall Stuart, Ghabbari Tayssir, Bosworth Andrew, Chakroun Mohamed, Varghese Anitha, Tiouiri Hanene, Ben Jemaa Mounir, Znazen Abir, Hewson Roger, Zhioua Elyes, Letaief Amel   +11 more
doaj   +1 more source