Results 61 to 70 of about 87,027 (145)

Antidepressant‐ and Anxiolytic‐Like Effect of the Froriepia subpinnata Extract in the Rat: Neurochemical Correlates

Brain and Behavior, Volume 14, Issue 11, November 2024.
The potential antianxiety and antidepressant effects of Froriepia subpinnata were explored. Behavioral tests, including the elevated plus‐maze, open field, sucrose preference, Morris water maze, and passive avoidance, were conducted. Real‐time PCR was employed to examine changes in the expression of candidate genes associated with stress response and ...
Mohammad R. Samandari‐Bahraseman, Keyvan Esmaeilzadeh‐Salestani, Manijeh Dogani, Banafsheh Khaleghdoust, Nima Hatami, Saeed Esmaeili‐Mahani, Leila Elyasi, Evelin Loit, Jaanus Harro   +8 more
wiley   +1 more source

Genoarchitectural Definition of the Adult Mouse Mesocortical Ring: A Contribution to Cortical Ring Theory

Journal of Comparative Neurology, Volume 532, Issue 7, July 2024.
Sagittal section of adult mouse brain showing selective layer2 expression of gene Lypd1 at the insular (Ins) and postrhinal (PoRh) cortex, representing rostrolateral and caudal parts of the mesocortical ring, with negative surrounding isocortical and allocortical areas.
Luis Puelles, Antonia Alonso, Elena García‐Calero   +2 more
wiley   +1 more source

Candidate genes in ocular dominance plasticity

Frontiers in Neuroscience, 2012
The objective of this study was to identify new candidate genes involved in experience-dependent plasticity. To this aim, we combined previously obtained data from recombinant inbred BXD strains on ocular dominance (OD) plasticity and gene expression ...
M. Liset Rietman, Jean-Pierre eSommeijer, Christiaan N. Levelt, J. Alexander Heimel   +3 more
doaj   +1 more source

Network pharmacology-based strategy to investigate pharmacological mechanisms of Zuojinwan for treatment of gastritis

BMC Complementary and Alternative Medicine, 2018
Background Zuojinwan (ZJW), a classic herbal formula, has been extensively used to treat gastric symptoms in clinical practice in China for centuries. However, the pharmacological mechanisms of ZJW still remain vague to date. Methods In the present work,
Guohua Yu, Wubin Wang, Xu Wang, Meng Xu, Lili Zhang, Lei Ding, Rui Guo, Yuanyuan Shi   +7 more
doaj   +1 more source

Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target

Molecular Pain, 2016
Burn injury is a cause of significant mortality and morbidity worldwide and is frequently associated with severe and long-lasting pain that remains difficult to manage throughout recovery.
Kathleen Yin BPharm, Jennifer R Deuis PhD, Richard J Lewis PhD, Irina Vetter PhD   +3 more
doaj   +1 more source

Activation of multiple receptors stimulates extracellular vesicle release from trophoblast cells

Physiological Reports, 2020
Reports of the stimulated release of extracellular vesicles (EVs) are few, and the mechanisms incompletely understood. To our knowledge, the possibility that the activation of any one of the multitudes of G‐protein‐coupled receptors (GPCRs) expressed by ...
Kirk P. Conrad, Kubra M. Tuna, Cathleen T. Mestre, Esha S. Banwatt, Abdel A. Alli   +4 more
doaj   +1 more source

Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex

eLife
Cholecystokinin (CCK) is an essential modulator for neuroplasticity in sensory and emotional domains. Here, we investigated the role of CCK in motor learning using a single pellet reaching task in mice.
Hao Li, Jingyu Feng, Mengying Chen, Min Xin, Xi Chen, Wenhao Liu, Liping Wang, Kuan Hong Wang, Jufang He   +8 more
doaj   +1 more source

Aptamer-Targeted Calcium Phosphosilicate Nanoparticles for Effective Imaging of Pancreatic and Prostate Cancer

International Journal of Nanomedicine, 2021
Thomas Abraham,1 Christopher O McGovern,2 Samuel S Linton,2 Zachary Wilczynski,3 James H Adair,3,4 Gail L Matters2 1Departments of Neural and Behavioral Sciences and the Microscopy Imaging Core Facility, The Pennsylvania State University College of ...
Abraham T, McGovern CO, Linton SS, Wilczynski Z, Adair JH, Matters GL   +5 more
doaj  

Identification of prognostic stemness-related genes in kidney renal papillary cell carcinoma

BMC Medical Genomics
Background Kidney renal papillary cell carcinoma (KIRP) is the second most prevalent malignant cancer originating from the renal epithelium. Nowadays, cancer stem cells and stemness-related genes (SRGs) are revealed to play important roles in the ...
Yifan Liu, Yuntao Yao, Yu Zhang, Chengdang Xu, Tianyue Yang, Mingyu Qu, Bingnan Lu, Xu Song, Xiuwu Pan, Wang Zhou, Xingang Cui   +10 more
doaj   +1 more source

Additional file 1: of Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

, 2018
Table S2. Clinical information of 93 BC patients. Abbreviations: BC, breast cancer; GB, gastric biopsy; F, female; +, lymphatic metastasis present; â , no lymphatic metastasis present; Y/N (GB column), examined/not examined; Y/N (stomach illness without GB column), those with/without stomach illness who did not undergo GB; IDC, invasive ductal cancer;
Meng, Li-Li, Wang, Jing-Long, Xu, Shu-Ping, Zu, Li-Dong, Yan, Zhao-Wen, Zhang, Jian-Bing, Han, Ya-Qin, Fu, Guo-Hui   +7 more
openaire   +1 more source