Results 51 to 60 of about 12,716 (189)
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda +4 more
wiley +1 more source
CCL11 and CCR3 protein levels in the inguinal lymph nodes.
, 2012 (A) Western blot analysis of CCL11 and its main receptor CCR3 in inguinal lymph nodes on day 7 p.i. Protein levels of both targets were increased in the congenic animals compared to the controls (data normalized to β- actin).
Johan Öckinger (150935) +11 more
core +1 more source
Scientific Reports, 2023 Chemokines are chemotactic cytokines that can cause directed migration of leukocytes. The aim of this study was to examine differences in single nucleotide polymorphisms (SNP) of chemokine in AITD patients compared to normal controls.
Chungwoo Shin +4 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Expression of wild type and variant (Ala23Thr) CCL11.
, 2018 Plasmids encoding the genes for wild type and variant (Ala23Thr) CCL11 were expressed in HEK cells and the expression levels determined by (A) EIA (triplicates; ***, pB) Coomassie Blue staining (triplicates).
Susan L. Neuhausen (238692) +10 more
core +1 more source
Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population
Journal of Neuroinflammation, 2012 Background Inflammatory mechanisms are important in stroke risk, and genetic variations in components of the inflammatory response have been implicated as risk factors for stroke.
Zhao Nan +11 more
doaj +1 more source
CCL11 (eotaxin‐1): A new diagnostic serum marker for prostate cancer [PDF]
The Prostate, 2012 AbstractBACKGROUNDThe recent recommendation of the U.S. Preventive Services Task Force against PSA‐based screening for prostate cancer was based, in part, on the lack of demonstrated diagnostic utility of serum PSA values in the low, but detectable range to successfully predict prostate cancer.
Agarwal, Manisha +4 more
openaire +3 more sources
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries +8 more
wiley +1 more source
Serum C-C motif ligand 11/Eotaxin-1 may serve as a candidate biomarker for postmenopausal osteoporosis [PDF]
Journal of Medical Biochemistry, 2019 Background: The chemokine C-C motif ligand 11, also known as eotaxin-1, has been identified as a novel mediator of inflammatory bone resorption. However, little is known regarding a potential role for CCL11/Eotaxin-1 in postmenopausal osteoporosis ...
Wang Wen +6 more
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