Results 21 to 30 of about 11,502 (179)

SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study.

PLoS ONE, 2018
BackgroundFibromyalgia (FM) is a chronic pain syndrome with a high incidence in females that may involve activation of the immune system. We performed exome sequencing on chemokine genes in a region of chromosome 17 identified in a genome-wide family ...
Zhifang Zhang, Jinong Feng, Allen Mao, Keith Le, Deirdre La Placa, Xiwei Wu, Jeffrey Longmate, Claudia Marek, R Paul St Amand, Susan L Neuhausen, John E Shively   +10 more
doaj   +3 more sources

Brexanolone infusion produces sustained anti-inflammatory and neurotrophic effects in patients with postpartum depression that predict symptom improvement [PDF]

Translational Psychiatry
Postpartum depression (PPD) is linked to neuroimmune dysregulation. Brexanolone, an intravenous formulation of the neurosteroid allopregnanolone and the first FDA-approved treatment for PPD, produces rapid and sustained antidepressant effects.
Irina Balan, Cecilia Isabel Sousa Pearson, Holly Krohn, Todd K. O’Buckley, Kai Xia, Samantha Meltzer-Brody, A. Leslie Morrow, Riah Patterson   +7 more
doaj   +2 more sources

CCL11 promotes angiogenic activity by activating the PI3K/Akt pathway in HUVECs

Journal of Receptor and Signal Transduction Research, 2017
CCR3, the receptor for CCL11, is expressed on the surface of immune cells and even on non-immune cells. CCL11-CCR3 interactions can promote cell migration and proliferation. In this study, we investigated the effect of CCL11 on angiogenesis in HUVECs and also examined the molecular mechanisms of this process.
Jun Young Park, Won Gil Cho, Byung Pil Cho   +2 more
exaly   +4 more sources

Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling [PDF]

Immunity & Ageing
Background The chemokine CCL11 is negatively correlated with cognitive function and is able to cause dysfunctions of synaptic plasticity. This research investigate whether CCL11 induce microglia senescence to damage synaptic plasticity and the protective
Sheng Tian, Tianyuan Ye, Chao Tian, Yipeng Zhang, He Li, Hui Shen, Youhua Xu, Xiaorui Cheng   +7 more
doaj   +2 more sources

Involvement of Eotaxins (CCL11, CCL24, CCL26) in Pathogenesis of Osteopenia and Osteoporosis

Iranian Journal of Public Health, 2020
Background: The purpose of this study was to investigate the role of eotaxin family members including C-C motif chemokine 11 (CCL11), C-C motif chemokine 24 (CCL24), and C-C motif chemokine 26 (CCL26) as the subgroups of CC-chemokine in patients affected
Hadis AHMADI, Hossein KHORRAMDELAZAD, Gholamhossein HASSANSHAHI, Mitra ABBASI FARD, Zahra AHMADI, Mojgan NOROOZI KARIMABAD, Majid MOLLAHOSSEINI   +6 more
doaj   +4 more sources

Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis

Biomedicines
Objective: The course of relapsing–remitting multiple sclerosis (RRMS) is highly variable and there is a lack of effective prognostic biomarkers. This study aimed to assess the potential prognostic value of the chemokines B lymphocyte chemoattractant ...
Işıl Peker, Hacer Eroğlu İçli, Belgin Mutluay, Burcu Yüksel, Zeynep Özdemir, Mesrure Köseoğlu, Aysu Şen, Dilek Ataklı, Aysun Soysal, Musa Öztürk   +9 more
doaj   +3 more sources

Up-regulation of CCL11 and CCL26 is associated with activated eosinophils in bullous pemphigoid

Clinical and Experimental Immunology, 2011
SummaryEosinophils contribute to the pathogenesis of bullous pemphigoid (BP) by secretion of proinflammatory cytokines and proteases. Trafficking of eosinophils into tissue in animal models and asthma depends on interleukin-5 and a family of chemokines named eotaxins, comprising CCL11, CCL24 and CCL26.
Claudia GÜNTHER, G Wozel, Meurer M
exaly   +4 more sources

Effect of CCL11 on In Vitro Myogenesis and Its Clinical Relevance for Sarcopenia in Older Adults [PDF]

Endocrinology and Metabolism, 2021
Background The C-C motif chemokine ligand 11 (CCL11) has been receiving attention as a potential pro-aging factor. Accordingly, it may be involved in muscle metabolism and sarcopenia, a key component of aging phenotypes.
Da Ae Kim, So Jeong Park, Jin Young Lee, Jeoung Hee Kim, Seungjoo Lee, Eunju Lee, Il-Young Jang, Hee-Won Jung, Jin Hoon Park, Beom-Jun Kim   +9 more
doaj   +1 more source

C–C motif chemokine CCL11 is a novel regulator and a potential therapeutic target in non-alcoholic fatty liver disease

JHEP Reports, 2023
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is characterised by accelerated lipid deposition, aberrant inflammation, and excessive extracellular matrix production in the liver.
Zhiwen Fan, Xinyue Sun, Xuelian Chen, Huimin Liu, Xiulian Miao, Yan Guo, Yong Xu, Jie Li, Xiaoping Zou, Zilong Li   +9 more
doaj   +1 more source

Eotaxin/CCL11 in idiopathic retroperitoneal fibrosis [PDF]

Nephrology Dialysis Transplantation, 2012
Idiopathic retroperitoneal fibrosis (IRF) is a rare fibro-inflammatory disorder characterized by a periaortic tissue which often encases the ureters causing acute renal failure. IRF histology shows fibrosis and a chronic inflammatory infiltrate with frequent tissue eosinophilia.
Mangieri D, CORRADI, Domenico, Martorana D, Malerba G, Palmisano A, Libri I, Bartoli V, Carnevali ML, GOLDONI, Matteo, GOVONI, Paolo, ALINOVI, Rossella, BUZIO, Carlo, Vaglio A.   +12 more
openaire   +6 more sources