Results 41 to 50 of about 13,208 (193)

CCL11 promotes HCC recurrence after liver surgery via activating immunosuppressive macrophages

open access: yes, 2022
Background Surgical stress and chronic inflammation seriously trigger chemokine-mediated dysregulations of the hepatic environment, resulting in tumor progression and recurrence after liver surgery.
Yeung, Oscar Wai Ho   +5 more
core   +1 more source

Eotaxin-1 (CCL11) up-regulation in tears during seasonal allergic conjunctivitis [PDF]

open access: yesGraefe's Archive for Clinical and Experimental Ophthalmology, 2004
To compare in-season eotaxin-1 levels in tears of patients suffering from seasonal allergic conjunctivitis (SAC) with (1) tears of normal subjects and (2) tears of SAC patients out of season.Tears of 11 SAC patients and six control volunteers were collected during the pollen season.
Eperon, S.   +5 more
openaire   +3 more sources

Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:Thymic stromal lymphoproetin (TSLP) is a cytokine secreted by the airway epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in asthma.
Gustavo Nino   +10 more
doaj   +1 more source

CCL11 (eotaxin‐1): A new diagnostic serum marker for prostate cancer [PDF]

open access: yesThe Prostate, 2012
AbstractBACKGROUNDThe recent recommendation of the U.S. Preventive Services Task Force against PSA‐based screening for prostate cancer was based, in part, on the lack of demonstrated diagnostic utility of serum PSA values in the low, but detectable range to successfully predict prostate cancer.
Agarwal, Manisha   +4 more
openaire   +3 more sources

Expression of wild type and variant (Ala23Thr) CCL11.

open access: yes, 2018
Plasmids encoding the genes for wild type and variant (Ala23Thr) CCL11 were expressed in HEK cells and the expression levels determined by (A) EIA (triplicates; ***, pB) Coomassie Blue staining (triplicates).
Susan L. Neuhausen (238692)   +10 more
core   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

open access: yesAdvanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu   +15 more
wiley   +1 more source

The chemokines CCL11, CCL20, CCL21, and CCL24 are preferentially expressed in polarized human secondary lymphoid follicles

open access: yes, 2004
Chemokines regulate cellular trafficking to and from lymphoid follicles. Here, the distribution pattern of four CCL chemokines is defined by in situ hybridization in human lymphoid follicles from tonsils and lymph nodes (LNs) of newborns and adults ...
Müller, Christoph   +4 more
core   +1 more source

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

open access: yesAdvanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum   +13 more
wiley   +1 more source

Effects of intense pulsed light treatment on tear cytokines and clinical outcomes in meibomian gland dysfunction.

open access: yesPLoS ONE, 2021
Meibomian gland dysfunction (MGD) has become a prevalent ocular surface disorder. Its pathogenesis is regarded as a self-perpetuating inflammatory vicious circle.
Qian Li   +6 more
doaj   +1 more source

CCL11 and CCR3 protein levels in the inguinal lymph nodes.

open access: yes, 2012
(A) Western blot analysis of CCL11 and its main receptor CCR3 in inguinal lymph nodes on day 7 p.i. Protein levels of both targets were increased in the congenic animals compared to the controls (data normalized to β- actin).
Johan Öckinger (150935)   +11 more
core   +1 more source

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