Results 91 to 100 of about 11,502 (179)

Inflammatory mediators and dual depression: Potential biomarkers in plasma of primary and substance-induced major depression in cocaine and alcohol use disorders.

PLoS ONE, 2019
Major depressive disorder (MDD) is the most prevalent comorbid mental disorder among people with substance use disorders. The MDD can be both primary and substance-induced and its accurate diagnosis represents a challenge for clinical practice and ...
Nuria García-Marchena, Marta Barrera, Joan Ignasi Mestre-Pintó, Pedro Araos, Antonia Serrano, Clara Pérez-Mañá, Esther Papaseit, Francina Fonseca, Juan Jesús Ruiz, Fernando Rodríguez de Fonseca, Magí Farré, Francisco Javier Pavón, Marta Torrens   +12 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, Volume 38, Issue 46, 18 August 2026.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Intermittent Hypoxia Exacerbates Lipopolysaccharide‐Induced Neurobehavioral Abnormalities: The Role of Neuroinflammation and Synaptic‐Related Proteins

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Background Sepsis is a common systemic inflammatory disease clinically observed in patients with severe trauma or infectious diseases. Lipopolysaccharide (LPS) serves as a classic tool for studying infection‐related neuroinflammation and behavioral changes.
Yi‐Zhu Ding, Zong‐Fang Wang, Chen Dai, Yuan‐Zi Ye   +3 more
wiley   +1 more source

Validity of serum CCL11 (Eotaxin-1) and interleukin-13 as prognostic biomarkers in hepatitis C virus induced liver disease

The Egyptian Journal of Internal Medicine
Background Hepatitis C virus (HCV) is the main cause of chronic liver disease (CLD), which affects more than 50 million people around the world. Persistent immune dysregulation promotes hepatocellular damage, fibrotic remodeling and carcinogenesis ...
Nasser Abdallah, Khaled Hussain, Akram Deghady, Samar Raky, Marwa Deif   +4 more
doaj   +1 more source

Selective Anti‐Inflammatory Actions of Curcumin on Cytokine Pathways in Major Depressive Disorder

Brain and Behavior, Volume 16, Issue 8, August 2026.
Curcumin partially attenuates IRS/M1/Th1 immune activation in MDD patients ex vivo, but fails to normalize it. Paradoxically, it upregulates immune profiles in healthy controls. Its immunomodulatory effects are state‐dependent, suggesting cautious use in non‐depressed individuals.
Tangcong Chen, Yueyang Luo, Mengqi Niu, Jing Li, Mengdie Li, Yingqian Zhang, Michael Maes   +6 more
wiley   +1 more source

Peripheral chemokine levels in women with recurrent major depression with suicidal ideation Níveis periféricos de quimiocina em mulheres com depressão maior com ideação suicida

Brazilian Journal of Psychiatry, 2012
OBJECTIVE: To compare serum levels of MCP-1/CCL2, RANTES/CCL5, and Eotaxin/CCL11 between female patients with recurrent major depressive disorder (MDD) and healthy controls, verifying if there is a difference in the levels of these mediators between ...
Rodrigo Grassi-Oliveira, Elisa Brieztke, Antônio Teixeira, Júlio Carlos Pezzi, Márcio Zanini, Rodrigo Pestana Lopes, Moisés Evandro Bauer   +6 more
doaj   +1 more source

Serum CCL11 Levels in Benign Prostatic Hyperplasia and Prostate Cancer

Urogenital Tract Infection, 2016
This work was supported by the research fund of Hanyang University (HY-2012) and by the National Research Foundation of Korea (NRF) funded by the Korean Government (MSIP) (NRF-2014R1A2A2A01005449).
Kyu-Shik Kim, Hong-Sang Moon, Sung-Yul Park, Hwan-Sik Hwang, Jung-Hyun Kim, Sang-Su Kim, Ik-Hwan Han, Ki-Jun Kim, Chang-Suk Noh, Jae-Sook Ryu   +9 more
openaire   +1 more source

Endothelial Atypical Receptors for Chemoattractants in Lung Immune Surveillance

European Journal of Immunology, Volume 56, Issue 8, August 2026.
Control of chemokine gradients within tissues is achieved by atypical chemokine receptors (ACKRs). The lungs require tightly regulated leukocyte recruitment for effective host defense while preventing tissue damage. In this context, ACKRs expressed by lung endothelial cells are emerging as critical regulators of leukocyte trafficking and inflammatory ...
Mattia Laffranchi, Eleonora Bonanni, Francesca Sozio, Miriam Turchetti, Giuseppe Sciumè, Marcus Thelen, Annalisa Del Prete, Raffaella Bonecchi, Silvano Sozzani   +8 more
wiley   +1 more source

Oral Spermidine Supplementation Preserves Submandibular Gland Function After Radiotherapy: Mechanistic Insights and Use in a Phase II Randomized Clinical Trial

MedComm, Volume 7, Issue 8, August 2026.
Radiotherapy‐induced xerostomia severely impairs quality of life. Integrated multiomics, organoids, murine models, and a randomized Phase II trial identified spermidine as a key radiation‐responsive metabolite. Oral spermidine preserved salivary gland function, maintained acinar cell integrity through Golgi‐mediated posttranslational modifications ...
Yu Min, Kun Gao, Yingtong Liu, Lei Dai, Xingchen Peng   +4 more
wiley   +1 more source

Genetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response

Molecular Cancer
Nucleic acid vaccines have shown promising potency and efficacy for cancer treatment with robust and specific T-cell responses. Improving the immunogenicity of delivered antigens helps to extend therapeutic efficacy and reduce dose-dependent toxicity ...
Hailong Qi, Zhongjie Sun, Tianle Gao, Yanling Yao, Yu Wang, Weiwei Li, Xudong Wang, Xiaofang Wang, Defang Liu, Jian-Dong Jiang   +9 more
doaj   +1 more source