Enzymatic Effectiveness of Alcoholic and Aqueous Extract of Salvia Officinalis in Mice Poisoned with Tetrachloride [PDF]
Regarding the antioxidant, anti-inflammatory, and antibacterial effects of Salvia officnalis (S. officinalis) extracts and the use of medicinal herbs as an alternative to chemical drugs, this study aimed to evaluate the enzymatic changes and reduction of
R Kadhim, N. H Ali, D Aziz Ibrahim
doaj +1 more source
Indirubin alleviates CCl4-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways [PDF]
Objective(s): Liver fibrosis is a common liver disease caused by chronic liver damage. However, there are currently no approved drugs available to treat it. Therefore, the therapeutic effect of indirubin on liver fibrosis was evaluated.
Xiaoying Li, Yuanzhi Yao, Lin Wei
doaj +1 more source
Evaluation of the ameliorative role of ginger (Zingiber officinale) extract against carbon tetrachloride-induced hepatotoxicity in male albino rats [PDF]
Background: One well-known hepatotoxin that is frequently used to cause acute toxic liver injury in a variety of experimental animals is carbon tetrachloride (CCl4).
Olfat Elghareeb +3 more
doaj +1 more source
This study aims to explore the ameliorative effects of L-glutamic acid (L-Glu) against carbon tetrachloride (CCl4) toxicity in male rats. Changes in the activities of alanine and aspartate aminotransferases (ALAT, ASAT) were studied in the tissues and ...
N. O. Salyha
doaj +1 more source
Carbon tetrachloride-induced acute liver toxicity: selecting dosage and biomarkers for evaluating hepatoprotective drugs in ICR outbred mice [PDF]
Evaluating effects of putative chemical or herbal agents against a single intraperitoneal administration of carbon tetrachloride (CCl4) in rodents is a widely used model for studying hepatoprotective potency.
Theerut Luangmonkong +9 more
doaj +1 more source
Hepatoprotective Role of Caesalpinia bonduc: A Histopathological and Biochemical Study [PDF]
Background: Hepatotoxicity is one of the inevitable side effects of long term use of medicines in many different disorders, chronic use of alcohol and in certain infectious disorders.
Suhani Sumalatha +3 more
doaj +1 more source
ObjectiveTo investigate the effects of carbon tetrachloride (CCl4) on cardiac function and morphology in rats with acute liver injury.MethodsRat models of acute liver injury were established by intraperitoneal injection with different concentrations of ...
ZHANG Lili +6 more
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The pharmacological effect of apricot seeds extracts and amygdalin in experimentally induced liver damage and hepatocellular carcinoma [PDF]
Introduction: Apricot (Prunus armeniaca L.) has been widely used for the treatment of several disorders such as liver diseases, but the hepatoprotective and anticancer activities of its seeds were not studied before.
Amer Ramadan +4 more
doaj +1 more source
Objective: To study the protective effect and potential mechanism of glycyrrhiza and pueraria fermentation composition on chronic liver injury induced by carbon tetrachloride (CCl4).
Jing WANG +4 more
doaj +1 more source
The Effect of Citrullus Colocynthis on Serum Lipid Profile and Hepatic Histology in CCl 4-Induced Liver Injury Rat Model [PDF]
Background: Chemical drugs in treatment of liver diseases are still scare and with many complications. Citrullus colocynthis known as bitter apple is on of herbals that can affect liver function. This study evaluated the effect of C. colocynthis on serum
Mina Fouzi +2 more
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