Distinct memory CD4<sup>+</sup> T cell subset tropism of two CCR5-tropic HIV-1 in a rapid progressor. [PDF]
Marichannegowda MH +11 more
europepmc +1 more source
Assembly of CCR5 with gp120 inhibits the HIV infectivity specifically in T cells. [PDF]
Appiah-Kubi J +12 more
europepmc +1 more source
Determination of conformations adopted by CXCR4 and CCR5 at the cell surface
Sunniva Yngvil Dyrhaug
openalex +1 more source
Circulating immune landscape and immune signatures in spontaneous HIV controllers. [PDF]
Navas A +14 more
europepmc +1 more source
C-C chemokine receptor type 5 activation stimulates adipocyte differentiation through ERK-dependent pathway. [PDF]
Chen LK +7 more
europepmc +1 more source
Promotion of the invasion and metastasis of breast cancer by B7-H3 through CCR5High tumor-associated macrophages. [PDF]
Dai T +8 more
europepmc +1 more source
Beyond monotherapy: Combination therapies for HIV-1 cure through joint application of neutralizing antibodies, genome editing, and reservoir management. [PDF]
Mao Q, Li L, Wen H.
europepmc +1 more source
The contributing role of CCR5 in dementia. [PDF]
Zheng T, Ye M, Zhou P.
europepmc +1 more source
Chemokine receptors in vascular biology: a review of current evidence, implications, and therapeutic targets for hypertension. [PDF]
Oliveira de Moraes LH +3 more
europepmc +1 more source
Related searches:
Spiropiperidine CCR5 antagonists
Bioorganic & Medicinal Chemistry Letters, 2009A novel series of CCR5 antagonists has been identified, utilizing leads from high-throughput screening which were further modified based on insights from competitor molecules. Lead optimization was pursued by balancing opposing trends of metabolic stability and potency. Selective and potent analogs with good pharmacokinetic properties were successfully
David M, Rotstein +17 more
openaire +2 more sources

