Results 231 to 240 of about 90,382 (271)

Distinct memory CD4<sup>+</sup> T cell subset tropism of two CCR5-tropic HIV-1 in a rapid progressor. [PDF]

open access: yesASM Case Rep
Marichannegowda MH   +11 more
europepmc   +1 more source

Assembly of CCR5 with gp120 inhibits the HIV infectivity specifically in T cells. [PDF]

open access: yesSci Rep
Appiah-Kubi J   +12 more
europepmc   +1 more source

Circulating immune landscape and immune signatures in spontaneous HIV controllers. [PDF]

open access: yesFront Immunol
Navas A   +14 more
europepmc   +1 more source

Spiropiperidine CCR5 antagonists

Bioorganic & Medicinal Chemistry Letters, 2009
A novel series of CCR5 antagonists has been identified, utilizing leads from high-throughput screening which were further modified based on insights from competitor molecules. Lead optimization was pursued by balancing opposing trends of metabolic stability and potency. Selective and potent analogs with good pharmacokinetic properties were successfully
David M, Rotstein   +17 more
openaire   +2 more sources

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