Results 91 to 100 of about 6,286 (187)

Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley   +1 more source

Neutrophil‐Macrophage Interactions Shape Inflammatory Macrophage Remodeling in Gastric Cancer During Chemo‐Immunotherapy

Cancer Science, Volume 117, Issue 8, Page 2115-2131, August 2026.
PD‐1 blockade combined with chemotherapy induces MHC‐II+ inflammatory neutrophils in gastric cancer, which engage in dynamic crosstalk with macrophages to remodel the tumor microenvironment toward a pro‐inflammatory state, thereby amplifying antitumor immune responses.
Keita H. Nagaoka, Hiroki Yamashita, Chiaki Mashima, Guoqiang Zhang, Hitoshi Saito, Tatsunori Minamide, Takuya Nakatsuru, Ryo Kamata, Shunsuke A. Sakai, Gaku Yamamoto, Tomoko Y. Morita, Kazuki Nakai, Yumi Hakozaki, Kumi Kinoshita, Yui Takahashi, Izuma Nakayama, Akihito Kawazoe, Sai M. Pulukuri, Yuko Ishii, Hiroshi Haeno, Yukie Kashima, Kohei Shitara, Tomonori Yano, Takeshi Saito, Akihiro Ohashi   +24 more
wiley   +1 more source

Systemic single‐cell analysis of GPP reveals treatment‐responsive and persistent immune signatures

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Soyoung Jeong, Seungbok Lee, Christine Suh‐Yun Joh, James G. Krueger, Hyun Je Kim, Seong Jin Jo, Jong‐Hee Chae   +6 more
wiley   +1 more source

Role of darunavir in the management of HIV infection

HIV/AIDS: Research and Palliative Care, 2009
R Monica Lascar, Paul BennThe Mortimer Market Centre, Camden PCT, London WC1E 6JBAbstract: There is an ongoing need for potent antiretroviral therapies to deal with the increasing pool of treatment-experienced patients with multiple drug resistance.
R Monica Lascar, Paul Benn
doaj  

Pharmacological and Genetic Targeting of Inflammatory Chemokine Receptors CCR1, CCR2, and CCR5 in Atherosclerosis: A Systematic Review and Meta-Analysis of Preclinical Studies. [PDF]

J Am Heart Assoc
Shoaran M, Caiazzo E, Morsy MI, Gurgone D, MacRitchie N, Bruzzese D, Ialenti A, Guzik TJ, Graham GJ, Maffia P.   +9 more
europepmc   +1 more source

CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines. [PDF]

Cancer Res, 2014
Sicoli D, Jiao X, Ju X, Velasco-Velazquez M, Ertel A, Addya S, Li Z, Andò S, Fatatis A, Paudyal B, Cristofanilli M, Thakur ML, Lisanti MP, Pestell RG.   +13 more
europepmc   +1 more source

Maraviroc for Stroke Recovery (MASTER): protocol for a phase 2 double-blind placebo-controlled randomised clinical trial. [PDF]

BMJ Open
Broc N, Byczynski G, Dirren E, Carrera E.   +3 more
europepmc   +1 more source

CCR5+ CD8+ T Cells Are Associated with Poor Response to PD-1 Blockade Therapy. [PDF]

Int J Mol Sci
Zhao Z, Liu Y, Wu Z, Qi C, Ning Y, Lin Y, Pang X, Qiang G, Wang W.   +8 more
europepmc   +1 more source

Modulation of Chemokine Activity for Enhanced Angiogenesis and Tissue Regeneration in Chronic Wounds. [PDF]

Int J Mol Sci
Adit GN, Srikanth K, Harithpriya K, Ganesan K, Ramkumar KM.   +4 more
europepmc   +1 more source

Chemokines and chemokine receptors in metabolic dysfunction-associated steatohepatitis: pathogenic mechanisms and clinical implications. [PDF]

Cell Mol Biol Lett
Yin M, Zhang Y, Liu S, Li X.
europepmc   +1 more source