Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis
Epilepsia, EarlyView.Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi +10 more
wiley +1 more source
Evaluating the predictive value of optical coherence tomography angiography metrics and central corneal thickness among glaucoma suspect patients: a comparative cross-sectional study. [PDF]
Med Hypothesis Discov Innov OphthalmolElsalhy FMAE +11 more
europepmc +1 more source
Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells
The FEBS Journal, EarlyView.Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari +6 more
wiley +1 more source
Screening and Diagnosis of Primary Aldosteronism in Patients Using Renin-Angiotensin System Inhibitors. [PDF]
J Clin Hypertens (Greenwich)Wang Q, Dong H, Li HW, Zou YB, Jiang XJ.
europepmc +1 more source
Automodification of N‐terminal serine residues facilitates PARP2 release from DNA
The FEBS Journal, EarlyView.PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar +6 more
wiley +1 more source
Comparison of corneal pachymetry evolution after accelerated corneal crosslinking in keratoconus eyes using anterior segment optical coherence tomography and Scheimpflug imaging. [PDF]
Int OphthalmolLang A +3 more
europepmc +1 more source
A Systematic Review Evaluating Methods for Diagnosis, Treatment and Prevention of Dental Erosions
International Journal of Dental Hygiene, EarlyView.ABSTRACT Aim The aim of this systematic review was to investigate the quality of evidence for methods used to diagnose, restore and prevent dental erosions, by evaluating and summarising clinical controlled studies and in situ studies covering this field.
Maria Skalsky Jarkander +5 more
wiley +1 more source
Comparison of two swept-source optical biometers in eyes with long axial length. [PDF]
Front Med (Lausanne)Tañá-Rivero P +4 more
europepmc +1 more source
The Effect of Myrtacine and Celastrol‐Enriched Extract on Cutibacterium acnes Extracellular Vesicles
International Journal of Dermatology, EarlyView.Myrtacine alone, Celastrol‐enriched extract alone, or the combination of both ingredients were added to the culture medium either before (preventive condition) or after (modulating condition) incubation with C. acnes IA1 extracellular vesicles (EVs) from healthy and acne skin in immortalized keratinocytes (HaCaT cells) and human skin explants.
Caroline T. Cheung +7 more
wiley +1 more source
Journal of Advanced Nursing, EarlyView.ABSTRACT Background Loneliness significantly affects the physical and mental health of older adults, particularly those in long‐term care settings. Despite the high prevalence of loneliness, comprehensive reviews on psychosocial interventions targeting loneliness in these populations are scarce.
Jodie Cheuk‐Yan Szeto +4 more
wiley +1 more source