Results 41 to 50 of about 368,667 (267)

Ten-year observation of corneal densitometry and associated factors following small incision lenticule extraction [PDF]

International Journal of Ophthalmology
AIM: To investigate the long-term changes of corneal densitometry (CD) and its contributing elements after small incision lenticule extraction (SMILE). METHODS: Totally 31 eyes of 31 patients with mean spherical equivalent of -6.46±1.50 D and mean age 28.
Xiao-Song Han, Fei Xia, Zhuo-Yi Chen, Pei-Jun Yao, Dong-Mei Yang, Jing Zhao, Xing-Tao Zhou   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Expression and significance of cell immunohistochemical markers (HHF-35, CD-31, Bcl-2, P-53 and apopDETEC) in hypertrophic cardiomyopathy.

Histology and histopathology, 2004
There are several hypotheses concerning the pathogenesis of hypertrophic cardiomyopathy (genetic, ischaemic, immune, inflammatory and apoptosis induction). We have studied three types of cardiomyopathy in order to observe the expression and assess the significance of different immunohistochemical markers (muscular actin, CD-31, proliferation cell ...
Martínez Díaz, F., Bernal-Gilar, M., Gómez Zapata., Maximiliano, Luna, A.   +3 more
openaire   +3 more sources

Reaching the boundary between stellar kinematic groups and very wide binaries. III. Sixteen new stars and eight new wide systems in the beta Pictoris moving group [PDF]

, 2015
Aims. We look for common proper motion companions to stars of the nearby young beta Pictoris moving group. Methods. First, we compiled a list of 185 beta Pictoris members and candidate members from 35 representative works.
Alonso-Floriano, F. J., Caballero, J. A., Cortes-Contreras, M., Montes, D., Solano, E.   +4 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

THE STUDY OF THE CORRELATION BETWEEN DOPPLER INDICES OF INTRATUMORAL BLOOD FLOW AND CD-31 IN MALIGNANT OVARIAN TUMORS OF EPITHELIAL ORIGIN

Bulletin of Problems Biology and Medicine, 2020
The correlation among quantitative indices (VI-vascular index, PI-pulsatility index, RI- resistive index, VFI-vascular flow indices) of dopplerometry with CD-31 in malignant ovarian tumors was sted. ROC examination of quantitative indices of doplerometry was also performed in malignant ovarian tumors.
A.T. Amiraslanov, N.G. Gibleliyeva, G.A. Ahmadova   +2 more
openaire   +1 more source

Switching from reference infliximab to CT-P13 in patients with inflammatory bowel disease: 12 months results [PDF]

, 2017
Background: Biological agents, such as infliximab, have transformed the outcomes of patients with immune-mediated inflammatory diseases. The advent of biosimilar treatment options such as CT-P13 promises to improve the availability of biological therapy,
Argüelles Arias, Federico, Castro Laria, Luisa, Guerra Veloz, María Fernanda, Maldonado Pérez, Belén, Merino Bohórquez, Vicente, Perea Amarillo, Raúl, Romero Gómez, Manuel, Vilches Arenas, Ángel   +7 more
core  

Discovery of magnetic fields in hot subdwarfs

, 2004
We present initial results of a project to measure mean longitudinal magnetic fields in a group of sdB/OB/O stars. The project was inspired by the discovery of three super-metal-rich sdOB stars, each having metals (e.g. Ti, V) enhanced by factors of 10^3
Aznar Cuadrado, Bagnulo, Bauer, Casini, Edelmann, Elkin, Groth, Heber, Heber, Heber, Husfeld, Jordan, Karl, Kawaler, Koester, Landstreet, Leone, Markiel, Ramspeck, S. Friedrich, S. J. O'Toole, S. Jordan, U. Heber, Winget   +23 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn’s disease

BMC Gastroenterology, 2012
Background Glycoprotein 2 (GP2) was discovered as the major autoantigen of Crohn’s disease (CD)-specific pancreatic autoantibodies (PAB). We investigated anti-GP2 IgA and IgG antibodies as novel serological parameters in CD and assessed their association
Bogdanos Dimitrios P, Roggenbuck Dirk, Reinhold Dirk, Wex Thomas, Pavlidis Polychronis, von Arnim Ulrike, Malfertheiner Peter, Forbes Alastair, Conrad Karsten, Laass Martin W   +9 more
doaj   +1 more source