Results 11 to 20 of about 31,883 (222)
Evaluation of Endoglin (CD105) expression in pediatric rhabdomyosarcoma [PDF]
BMC Cancer, 2018 Background The Intratumoral Microvessel Density (IMVD) is commonly used to quantify tumoral vascularization and is usually assessed by pan-endothelial markers, such as CD31.
Virginia Di Paolo +13 more
doaj +7 more sources
Endoglin Expression (CD105) in Ephithelial Ovarian Cancer [PDF]
Indonesian Journal of Obstetrics and Gynecology, 2018 Objective: Endoglin ( CD105 ) is one of the factors that play a role in vascular development , angiogenesis and vascular homeostasis. The aim of this research is to address the endoglin expression (CD105) in primary tumor and metastasis tumor (omentum ...
Rizkinov Jumsa +3 more
doaj +4 more sources
Overexpression of CD105 in rat myoblasts: Role of CD105 in cell attachment, spreading and survival [PDF]
International Journal of Oncology, 2004 CD105 is a receptor for transforming growth factor-beta but it is also considered to be involved in cellular functions such as cell adhesion and migration. Using CD105 transfected rat myoblasts, we have investigated the role of CD105 in cell adhesion, spreading, growth and migration.
Guo, Baoqiang +8 more
openaire +6 more sources
CD105 prevents apoptosis in hypoxic endothelial cells [PDF]
Journal of Cell Science, 2003 CD105, a marker of endothelial cells, is abundantly expressed in tissues undergoing angiogenesis and is a receptor for transforming growth factorβ. The pivotal role of CD105 in the vascular system was demonstrated by the severe vascular defects that occur in CD105-knockout mice,but the exact mechanisms for CD105 regulation of vascular development have ...
Li, Chenggang +6 more
openaire +7 more sources
Endoglin (CD105) expression in sinonasal polyposis [PDF]
European Archives of Oto-Rhino-Laryngology, 2015 Despite appropriate surgical therapy, 5-10 % of patients with chronic rhinosinusitis (CRS) and nasal polyps (NP) experience disease recurrences. It has been suggested that angiogenesis may relate to the pathogenesis and prognosis of CRS with NP. Endoglin (CD105) is a component of the receptor complex of transforming growth factor-beta, a pleiotropic ...
OTTAVIANO, GIANCARLO +11 more
openaire +4 more sources
CD105 is important for angiogenesis: evidence and potential applications [PDF]
The FASEB Journal, 2003 ABSTRACT Angiogenesis is the propelling force for tumor growth and metastasis, and antiangiogenic therapy represents one of the most promising modalities for cancer treatment. CD105 (endoglin) is a proliferation‐associated and hypoxia‐inducible protein abundantly expressed in angiogenic endothelial cells (EC).
Duff, Sarah E. +3 more
openaire +3 more sources
On the origin of (CD105+) circulating endothelial cells [PDF]
Thrombosis and Haemostasis, 2009 SummaryCells designated by the CellSearch™ assay as circulating endothelial cells (CEC) (CD146+/CD105+/CD45− nuclear cells) are thought to derive from damaged vasculature.As CD105 has been suggested to be expressed by endothelial cells from malignant vasculature particularly, it is currently unknown whether this assay is suitable to determine CECs in ...
Strijbos, Michiel +3 more
openaire +4 more sources
Glioblastoma CD105+ cells define a SOX2− cancer stem cell-like subpopulation in the pre-invasive niche [PDF]
Acta Neuropathologica Communications, 2022 Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular hierarchy in GBM and have a determining role in tumor growth, recurrence and patient prognosis.
Jiaxin Li +4 more
doaj +2 more sources
Antagonizing CD105 enhances radiation sensitivity in prostate cancer [PDF]
Oncogene, 2018 Radiation therapy is the primary intervention for nearly half of the patients with localized advanced prostate cancer and standard of care for recurrent disease following surgery. The development of radiation-resistant disease is an obstacle for nearly 30-50% of patients undergoing radiotherapy.
Anisha Madhav +9 more
openaire +7 more sources
CD105 (Endoglin), Apoptosis, and Stroke [PDF]
Stroke, 2004 To the Editor: The recent paper by Zhu et al1 in this journal provides an insight into the possible mechanism of hypoxia-induced upregulation of CD105 (endoglin). The following 3 points are relevant to their paper. Lately there has been a major debate regarding the relevance of cell culture/animal models for human stroke in general and for ...
Guo, Baoqiang +4 more
openaire +3 more sources