Results 151 to 160 of about 33,329 (197)
Decoding the Oncogenic Role of GNG10 in Colorectal Cancer: A Non-Canonical Wnt Pathway-Driven Mechanism. [PDF]
Zhang X +6 more
europepmc +1 more source
LINC01770 Is Associated with Stem-like Features and Aggressive Traits in Breast Cancer Cells Through a Putative miR-335-5p/OCT4 Axis. [PDF]
Gasson J +4 more
europepmc +1 more source
Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells [PDF]
The cancer stem cell hypothesis posits that malignant growth arises from a rare population of progenitor cells within a tumor that provide it with unlimited regenerative capacity. Such cells also possess increased resistance to chemotherapeutic agents. Resurgence of chemoresistant disease after primary therapy typifies epithelial ovarian cancer and may
Susan K. Murphy, Eiji Kondo, R C Bentley
exaly +3 more sources
Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas [PDF]
A number of recent reports have demonstrated that only CD133-positive cancer cells of glioblastoma multiforme (GBM) have tumor-initiating potential. These findings raise an attractive hypothesis that GBMs can be cured by eradicating CD133-positive cancer stem cells (CSCs), which are a small portion of GBM cells.
Xun Jin, Do-Hyun Nam, Kyeung Min Joo
exaly +3 more sources
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Differential characteristics of CD133+ and CD133− Jurkat cells
In Vitro Cellular & Developmental Biology - Animal, 2015T cell acute lymphoblastic leukemia (T-ALL) is a hematological disease including malignancy of T cell precursors. There are some T-ALL patients that are drug-resistant. A major cause of treatment failure in cancers can be associated with the existence of cancer stem cells.
Azadeh, Anbarlou +5 more
openaire +2 more sources
International Journal of Radiation Oncology Biology Physics, 2007
Primary medulloblastoma and glioblastoma multiforme tumor cells that express the surface marker CD133 are believed to be enriched for brain tumor stem cells because of their unique ability to initiate or reconstitute tumors in immunodeficient mice. This study sought to characterize the radiobiological properties and marker expression changes of CD133 ...
Ed R, Blazek +2 more
exaly +3 more sources
Primary medulloblastoma and glioblastoma multiforme tumor cells that express the surface marker CD133 are believed to be enriched for brain tumor stem cells because of their unique ability to initiate or reconstitute tumors in immunodeficient mice. This study sought to characterize the radiobiological properties and marker expression changes of CD133 ...
Ed R, Blazek +2 more
exaly +3 more sources
Expression of CD133–1 and CD133–2 in ovarian cancer
International Journal of Gynecological Cancer, 2008Cancer stem cells have been isolated from several solid tumors including prostate, colon, liver, breast, and ovarian cancer. Stem cells isolated from nervous system and prostate express CD133 antigen, which is widely used to isolate hematopoietic stem and progenitor cells.
G. Ferrandina +12 more
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The Journal of Pathology, 2007
AbstractCD133 (prominin‐1) was the first in a class of novel pentaspan membrane proteins to be identified in both humans and mice, and was originally classified as a marker of primitive haematopoietic and neural stem cells. Due to the highly restricted expression of CD133 family molecules on plasma membrane protrusions of epithelial and other cell ...
D, Mizrak, M, Brittan, M R, Alison
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AbstractCD133 (prominin‐1) was the first in a class of novel pentaspan membrane proteins to be identified in both humans and mice, and was originally classified as a marker of primitive haematopoietic and neural stem cells. Due to the highly restricted expression of CD133 family molecules on plasma membrane protrusions of epithelial and other cell ...
D, Mizrak, M, Brittan, M R, Alison
openaire +2 more sources
Expression of CD133 in Synovial Sarcoma
Applied Immunohistochemistry & Molecular Morphology, 2010The development of synovial sarcoma, a translocationally defined soft tissue tumor of unknown histogenesis with considerable resistance to systemic therapy and a poor prognosis, may involve cancer stem-like cells. Recent studies suggest that synovial sarcoma arises from a primitive progenitor-type cell and have shown that synovial sarcomas contain ...
Jefferson, Terry, Torsten, Nielsen
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Egyptian Journal of Pathology, 2012
Background In chronic inflammation, an active interplay between cancer stem cells (CSCs) and the tumor microenvironment including carcinoma-associated fibroblasts (CAFs) has emerged as a necessary mechanism of carcinogenesis. However, the precise molecular events remain unclear.
Rasha M. Abd El Atti, Riham M. Abu-Zeid
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Background In chronic inflammation, an active interplay between cancer stem cells (CSCs) and the tumor microenvironment including carcinoma-associated fibroblasts (CAFs) has emerged as a necessary mechanism of carcinogenesis. However, the precise molecular events remain unclear.
Rasha M. Abd El Atti, Riham M. Abu-Zeid
openaire +1 more source

