Results 91 to 100 of about 188,070 (188)
Xiaoying Xu,1 Qiongli Zhai,1 Hao Jin,2 Yong Yu,3 Dongmei Han,2 Huilai Zhang,4 Kai Fu,5 Bin Meng1 1Department of Pathology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer ...
Xu X +7 more
doaj
Prostasome to sperm transfer of CD13/aminopeptidase N(EC 3.4.11.2)
Prostasomes are membranous vesicles (150-200 nm in diameter) that are present in human semen. They are secreted by the prostate gland and contain large amounts of cholesterol, sphingomyelin and Ca2+.
ARIENTI, Giuseppe +4 more
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Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes. [PDF]
Aminopeptidase N/CD13 is highly expressed by fibroblast like synoviocytes (FLS) and may play a role in rheumatoid arthritis (RA). CD13 was previously detected in human synovial fluid where it was significantly increased in RA compared to osteoarthritis ...
Kevin C Chung +17 more
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CD13 is upregulated in FLS at the mRNA level but the effects on CD13 protein levels are varied.
FLS were stimulated over a time course of 0–72 hours with IFNγ (1000U/ml), TNFα (10ng/ml), or IL-17 (10ng/ml). Cells were harvested and processed for either mRNA (A), surface expression (B), total cell lysate CD13 (C), or total CD13 in supernatant (D ...
Kevin C. Chung (3132753) +8 more
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El objetivo de este trabajo fue comparar el ultramicrométodo inmunocitoquímico (UMICIQ) con la citometría de flujo (CMF), para el diagnóstico inmunológico de la leucemia linfoide aguda (LLA) pediátrica. Se procesó la médula ósea de 30 pacientes con LLA y
Vianed Marsán-Suárez +6 more
doaj
Background: Immunophenotyping by flowcytometry improves both the accuracy and reproducibility of an acute leukemia (AL) diagnosis. The morphologically similar blast cells can be easily differentiated by immunophenotyping based on expression and different
Monika Sharma +4 more
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Generation and characterization of the CD13/aminopeptidase N knockout mouse
The major goal of our laboratory is to study the functions of membrane bound peptidase CD 13/Aminopeptidase N in normal physiology, as well as in disease states.
Winnicka, Beata
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The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion. [PDF]
Aminopeptidase N (CD13) is a widely expressed cell surface metallopeptidase involved in the migration of cancer and endothelial cells. Apart from our demonstration that CD13 modulates the efficacy of tumor necrosis factor-α-induced apoptosis in ...
Edwin R Chilvers +24 more
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Human umbilical cord blood: immunophenotypic heterogeneity of CD34+ hematopoietic progenitor cells
BACKGROUND: Human umbilical cord blood (HUCB) is a possible alternative to bone marrow (BM) and mobilized peripheral blood (PB) for transplantation of hematopoietic progenitors.
G D'Arena +5 more
doaj
Aminopeptidase‐N/CD13 is a potential proapoptotic target in human myeloid tumor cells
International audienceThe transmembrane metalloprotease aminopeptidase-N (APN)/CD13 is overexpressed in various solid and hematological malignancies in humans, including acute myeloid leukemia (AML) and is thought to influence tumor progression. Here, we
Brigitte Bauvois +11 more
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