Results 211 to 220 of about 131,028 (295)

CXCL2/CXCR2 pathway regulates CD169^high large macrophages to promote progression of malignant pleural effusion from lung adenocarcinoma. [PDF]

Front Med (Lausanne)
Chen S, Li C, Sun Y, Huang Y, Gong G, Bao Y, Xu L.   +6 more
europepmc   +1 more source

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

Cell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu, Bingyu Cai, Tingting Gao, Wumei Wei, Liu Wang, Qi Zhou, Wei Li, Jie Hao, Jun Wu   +8 more
wiley   +1 more source

Mendelian Randomization and Experimental Validation Identify Key Immune Signatures in Bullous Pemphigoid. [PDF]

Clin Cosmet Investig Dermatol
Wang Z, Cui H, Meng L, Yang X, Ye J.
europepmc   +1 more source

Flow cytometric identification of plasmacytoid dendritic cells in acute myeloid leukaemia: Challenges and practical considerations

British Journal of Haematology, EarlyView.
Mariana S. Vieira, Pietro B. Belmonte, Natália A. Marcondes, Raquel Q. Vidal, Flavo B. Fernandes, Liane N. Rotta   +5 more
wiley   +1 more source

A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells

Cell Proliferation, EarlyView.
This study presents a 3D bioprinted platform using gelatin‐hyaluronic acid hydrogels to enhance primary AML cell survival and proliferation while preserving stem‐like properties in vitro. By recapitulating in vivo‐like metabolic activity and drug resistance, this system offers a robust tool for preclinical drug screening and personalised therapy ...
Wanling Huang, Bo Deng, Nini Guo, Yiyi Ding, Zhangjingwen Xu, Yiwen Lu, Yue Ma, Qian Ren, Nan Wang, Pengyu Huang, Xiaotong Ma   +10 more
wiley   +1 more source

Macrophage polarization modulates neutrophil extracellular trap dynamics and reciprocal macrophage responses. [PDF]

Front Immunol
Blum L, Jäger K, Jones M, Elrod J, Boettcher M, Knopf J.   +5 more
europepmc   +1 more source

Magnesium Enhances Immune Clearance of P. gingivalis in Macrophages by Suppressing MCU‐Mediated Mitochondrial Calcium Overload

Cell Proliferation, EarlyView.
Magnesium restores macrophage clearance of P. gingivalis by inhibiting MCU‐mediated calcium overload. P. gingivalis is mainly phagocytosed by macrophages but escapes intracellular clearance via MCU‐mediated mitochondrial and cytosolic Ca2+ overload in periodontitis. The persistent P.
Dao‐Kun Deng, Meng‐Jie Su, Min‐Yi Zhang, Yu‐Jie Tan, Wenyao Kongling, Hong‐Yu Wang, Mei Xu, Shi‐Yu Liu, Xiao‐Tao He, Fa‐Ming Chen, Bei‐Min Tian, Xuan Li   +11 more
wiley   +1 more source

Longitudinal Dynamics of the Blood Proteome Within the Alzheimer Spectrum in Down Syndrome. [PDF]

Neurology
Wagemann O, Nuebling GS, Sandkühler K, Wlasich E, Loosli SV, Prix C, Stockbauer AC, Marth L, Forte A, Vöglein J, Katzdobler S, Bernhardt AM, Martinez-Murcia FJ, Jiménez-Mesa C, Höglinger GU, Levin J.   +15 more
europepmc   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source