Results 311 to 320 of about 188,530 (334)

Prediction of outcome using CD14++CD16−, CD14++CD16+ and CD14+CD16++ monocyte subpopulations in patients with complicated intra-abdominal infections

Medical Microbiology and Immunology, 2023
There is still no study investigating the prognostic performance of CD14++CD16-, CD14++CD16+ and CD14+CD16++ monocyte subpopulations in complicated intra-abdominal infections (cIAIs); therefore, we aimed to evaluate the association between monocyte subtypes and outcome in such patients.
Evgeni Dimitrov, Krasimira Halacheva, Georgi Minkov, Emil Enchev, Yovcho Yovtchev   +4 more
openaire   +2 more sources

CD14++CD16− and CD14+CD16+ human monocyte adhesion to endothelial cells

Cell and Tissue Biology, 2010
Two subsets of monocytes were identified in humans and other mammals blood based on different levels of CD14 and CD16 expression. These subsets have different patterns of adhesion molecules and chemokine receptors, which suggest different modes of interaction with endothelium and tissue traffic. Here, we investigated the ability of CD14+CD16+ and CD14++
E A, Starikova, A M, Lebedeva, I S, Freĭdlin   +2 more
openaire   +2 more sources

Anti-CD14 Antibody-treated Neutrophils Respond to LPS: Possible Involvement of CD14 Upregulated by Anti-CD14 Antibody Binding

Immunological Investigations, 2016
CD14 and Toll-like receptor 4/MD2 (TLR4/MD2) mediate the action of LPS on neutrophils. The anti-CD14 antibody and the TLR4/MD2-antagonist, synthetic lipid IVa (LA-14-PP), are known to inhibit the response of neutrophils to LPS. We studied the role of CD14 in LPS-induced priming of neutrophils for enhanced release of the superoxide anion.
Terukazu, Sanui, Masaaki, Takeshita, Takao, Fukuda, Akira, Haraguchi, Yoshitomi, Aida, Fusanori, Nishimura   +5 more
openaire   +2 more sources

Monoclonal antibodies to equine CD14

Veterinary Immunology and Immunopathology, 2010
CD14 is a receptor for the complex of lipopolysaccaride (LPS) and LPS-binding protein. Binding of this complex to CD14 in association with Toll-like receptor 4 provides a major pathway for the initiation of innate immune responses to bacterial pathogens.
Esther, Kabithe, Julie, Hillegas, Tracy, Stokol, James, Moore, Bettina, Wagner   +4 more
openaire   +2 more sources

Influence of CD14 polymorphism on CD14 expression in patients with extensive burns

Burns, 2009
We sought to investigate the association of CD14 genotype with the risk of mortality after burn, and we also attempted to evaluate whether CD14-159 C/T polymorphism affects the kinetics and extent of CD14 expression as well as its release, and TNF-alpha expression in burned patients.
Jing, Lin, Yong-ming, Yao, Ning, Dong, Jia-ke, Chai, Yan, Yu, Xiao-xia, Hou, Jing-min, Zhu, Zhi-yong, Sheng   +7 more
openaire   +2 more sources

CD14 C(−260)T gene polymorphism, circulating soluble CD14 levels and arteriosclerosis

Journal of Hypertension, 2004
CD14 pathway is at the crossroads between infection and inflammation. In human pathology, divergent results have been reported on the relationship between a polymorphism in the promoter of receptor CD14 (C260T), expression of soluble CD14 (sCD14) receptor and atherosclerosis. The aim of the study was to investigate in a cross-sectional population-based
Jacques, Amar, Jean-Bernard, Ruidavets, Claire, Bal dit Sollier, Vanina, Bongard, Henri, Boccalon, Bernard, Chamontin, Ludovic, Drouet, Jean, Ferrières   +7 more
openaire   +2 more sources

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2009
The term acute bronchiolitis is used to describe the clinical syndrome that consists of respiratory distress and wheezing from a viral lower respiratory tract infection in children until the age of two years. RSV is the most common pathogen and it affects nearly 100% of children in the first two years of life.
openaire   +1 more source

Lipopolysaccharide Regulates Macrophage Fluid Phase Pinocytosis Via CD14-Dependent and CD14-Independent Pathways

Blood, 1999
Lipopolysaccharide (LPS) is a mediator of inflammation and septic shock during bacterial infection. Although monocytes and macrophages are highly responsive to LPS, the biological effects of LPS in these cell types are only partially understood. We decided, therefore, to investigate the influence of LPS on macrophage pinocytosis and Fc receptor ...
Peppelenbosch, M. P., DeSmedt, M., ten Hove, T., van Deventer, S. J., Grooten, J.   +4 more
openaire   +3 more sources

CD14 polymorphisms and serum CD14 levels through childhood: A role for gene methylation?

Journal of Allergy and Clinical Immunology, 2010
CD14 is a pattern-recognition receptor for environmental LPS, and engagement of the CD14-LPS complex activates innate host defense mechanisms. Single nucleotide polymorphisms (SNPs) in the CD14 gene have been associated with soluble CD14 (sCD14) levels, but inconsistencies between studies suggest the presence of regulatory mechanisms hitherto not well ...
Monica Cheng, Munthe-Kaas, Tale Maehre, Torjussen, Kristina, Gervin, Karin C, Lødrup Carlsen, Kai Håkon, Carlsen, Berit, Granum, Hanne Sagsveen, Hjorthaug, Dag, Undlien, Robert, Lyle   +8 more
openaire   +2 more sources

?????????????? ???????????????????????? C159T ???????? ?????????????????? CD14 ???? ???????????????????????????????????? ?????????????????? ?? ???????????????? ?????????????? ???????????????????????? ????????????

2015
?????????????? ???????? ?????????????????????????????????????? ?????????????????? ?????????????? ?????? ???????????????????????? (C159T) CD14 ?????????????????? ?? ???????????????? ???????????? ???? ?????????????????????? ??????????. ?? ?????????????????????? ???????? ???????????????? 331 ?????????????? ?? ???????????????????????? ???????????? ?? 92 ???
openaire   +3 more sources