The impact of CD14 polymorphisms on the development of soluble CD14 levels during infancy [PDF]
CD14 is a receptor involved in the recognition of lipopolysaccharide and other bacterial wall components that may be involved in the balance between infectious and allergic disease and the early polarization towards TH1. Our group has shown an association between polymorphisms in the 5' flanking region of the CD14 gene and plasma soluble CD14 (sCD14 ...
T D, LeVan +7 more
openaire +2 more sources
Objective: to study the indicators of the monocyte-derived component of the immune system in kidney transplant recipients with satisfactory early and delayed renal transplant function. Materials and methods.
S. V. Zybleva, S. L. Zyblev
doaj +1 more source
Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands [PDF]
Conventionally, human monocyte sub-populations are classified according to surface marker expression into classical (CD14(++)CD16(-)), intermediate (CD14(++)CD16(+)) and non-classical (CD14(+)CD16(++)) lineages. The involvement of non-classical monocytes,
Brunisholz, René +11 more
core +1 more source
Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1 [PDF]
AbstractLipoproteins or lipopeptides (LP) are bacterial cell wall components detected by the innate immune system. For LP, it has been shown that TLR2 is the essential receptor in cellular activation. However, molecular mechanisms of LP recognition are not yet clear.
Maria, Manukyan +8 more
openaire +2 more sources
Characterization of the CD14++CD16+ monocyte population in human bone marrow. [PDF]
Numerous studies have divided blood monocytes according to their expression of the surface markers CD14 and CD16 into following subsets: classical CD14(++)CD16(-), intermediate CD14(++)CD16(+) and nonclassical CD14(+)CD16(++) monocytes.
Manuela Mandl +3 more
doaj +1 more source
Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E. +70 more
core +1 more source
CD14+CD16+ and CD14+CD163+ monocyte subpopulations in kidney allograft transplantation [PDF]
Monocytes represent a heterogeneous population of cells subdivided according to the expression level of membrane antigens. A pro-inflammatory (intermediate/nonclassical) subpopulation of monocytes is defined by expression of CD16. CD163 seems to be characteristically preferentially expressed by immunosuppressive monocytes.
Sekerkova, Alena +6 more
openaire +2 more sources
BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY
. We have observed thirty-six patients with coronary artery disease (CAD) who have undergone coronary artery bypass graft (CABG) surgery. In patients with uncomplicated clinical course post-CABG, total lymphocyte counts, T-, B- and NK-cell contents did ...
A. S. Golovkin +5 more
doaj +1 more source
Interaction of CD14 haplotypes and soluble CD14 on pulmonary function in agricultural workers [PDF]
Agricultural environments are contaminated with organic dusts containing bacterial components. Chronic inhalation of organic dusts is implicated in respiratory diseases. CD14 is a critical receptor for gram-negative lipopolysaccharide; however, its association with respiratory disease among agricultural workers is unknown.
LeVan, Tricia D. +6 more
openaire +3 more sources
. This article is devoted to analysis of gene polymorphisms affecting CD14 regulatory molecule, as well as IL-1β, TNFα cytokines and IL-1RN in the patients with nosocomial pneumonias.
E. A. Baygosina, V. I. Sovalkin
doaj +1 more source

