Results 41 to 50 of about 131,028 (295)

CD14 and CD16 expression in noninfectious granulomatous skin diseases

Journal of Cutaneous Immunology and Allergy, 2020
Objectives Peripheral blood monocytes are categorized as classical (CD14++/CD16−) or nonclassical (CD14−/CD16+ and CD14+/CD16+) based on their CD14 expression and CD16 expression. Maturation of classical monocytes produces CD14+/CD16+ macrophages.
Yuta Ito, Maki Kitakawa, Sachiko Koshikawa, Hideaki Watanabe, Hirohiko Sueki   +4 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Acute and chronic histopathologic changes in wild type or TLR-2-/-, TLR-4-/-, TLR-6-/-, TLR-9-/-, CD14-/-, and MyD-88-/- mice experimentally infected with Plasmodium chabaudi

Brazilian Journal of Veterinary Pathology, 2011
Malaria is caused by protozoan parasites of the genus Plasmodium, which is transmitted by Anopheline mosquitoes. Experimental murine models using rodent malaria are useful for studying pathologic aspects of severe malaria.
Ana Patrícia C. Silva, Soraia C. O. Rodrigues, Fernanda A. Merlo, Tatiane A. Paixão, Renato L. Santos   +4 more
doaj   +1 more source

Dopamine increases CD14+CD16+ monocyte migration and adhesion in the context of substance abuse and HIV neuropathogenesis. [PDF]

PLoS ONE, 2015
Drug abuse is a major comorbidity of HIV infection and cognitive disorders are often more severe in the drug abusing HIV infected population. CD14+CD16+ monocytes, a mature subpopulation of peripheral blood monocytes, are key mediators of HIV ...
Jacqueline S Coley, Tina M Calderon, Peter J Gaskill, Eliseo A Eugenin, Joan W Berman   +4 more
doaj   +1 more source

Роль полиморфизма С(-260)→Т гена CD14 в течении и исходе нозокомиальной пневмонии [PDF]

, 2009
Изучена ассоциация полиморфизма гена рецептора CD14 в позиции С(-260)→Т с частотой возникновения, тяжестью течения и исходом нозокомиальной пневмонии (НП).
М. И. Воевода, Т. А. Потапова, А. Г. Ромащенко, Е. А. Байгозина, В. И. Совалкин, И. В. Куликов   +5 more
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Helicobacter pylori Infection Enhances Gastric Mucosal Inflammation in Individuals Carrying the 260-T Allele of the CD14 Gene

Gut and Liver, 2013
Background/AimsWe aim to evaluate the association between promoter polymorphism of the clusters of differentiation 14 (CD14) gene and Helicobacter pylori-induced gastric mucosal inflammation in a healthy Korean population.Methods : The study population ...
doaj   +1 more source

A TLR4-independent critical role for CD14 in intracellular LPS sensing

Cell Reports, 2022
Summary: Intracellular lipopolysaccharide (LPS) sensing by the noncanonical inflammasome comprising caspase-4 or -11 governs antibacterial host defense. How LPS gains intracellular access in vivo is largely unknown. Here, we show that CD14—an LPS-binding
Swathy O. Vasudevan, Ashley J. Russo, Puja Kumari, Sivapriya Kailasan Vanaja, Vijay A. Rathinam   +4 more
doaj   +1 more source

Binding of Bacterial Peptidoglycan to CD14 [PDF]

Journal of Biological Chemistry, 1998
The hypothesis that soluble peptidoglycan (sPGN, a macrophage-activator from Gram-positive bacteria) binds to CD14 (a lipopolysaccharide (LPS) receptor) was tested. sPGN specifically bound to CD14 in the following three assays: binding of soluble 32P-CD14 (sCD14) to agarose-immobilized sPGN, enzyme-linked immunosorbent assay, and photoaffinity cross ...
R, Dziarski, R I, Tapping, P S, Tobias
openaire   +2 more sources

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source