Results 141 to 150 of about 5,434 (169)
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Physical association between CD155 and CD44 in human monocytes
Molecular Immunology, 1997Regulation of CD44-mediated binding to hyaluronan is critical in normal and diseased immune cell function. In earlier work by others (Shepley and Racaniello, J. Virol., 68, 1301 1309), anti-CD44 mAb blocked poliovirus binding to CD155 (the poliovirus receptor) in HeLa cells, suggesting that CD155 and CD44 may be physically associated.
M S, Freistadt, K E, Eberle
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PVR/CD155 Ala67Thr Mutation and Cleft Lip/Palate
Journal of Craniofacial Surgery, 2018Abstract The 19q13 locus has been linked to cleft lip and palate by our group and independently by others. Here we fine mapped the region in an attempt to identify an etiological variant that can explain cleft lip and palate occurrence. A total of 2739 individuals born with cleft lip and palate, related to individuals born with
Alexandre R, Vieira +8 more
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CD155 Expression in Early-Stage Lung Adenocarcinoma
The Annals of Thoracic SurgeryCluster of differentiation (CD) 155 is a transmembrane protein that belongs to the nectin-like molecule family, which is widely overexpressed in several types of cancer. However, the clinical significance of CD155 in pathologic stage I lung adenocarcinoma remains poorly understood.We analyzed 320 patients diagnosed with pathologic stage I lung ...
Kyoto, Matsudo +10 more
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Expression and possible role of PVR/CD155/Necl-5 in osteoclastogenesis
Molecular and Cellular Biochemistry, 2007Osteoclasts, the bone-resorbing cells, are differentiated from hematopoietic precursors via two-step cell-cell interactions. One is the interaction between the osteoclast precursor and the stromal cell to initiate differentiation. The other is the interaction among osteoclast precursors to form multinucleated osteoclasts.
Saori, Kakehi +2 more
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CD155-TIGIT Axis as a Therapeutic Target for Cancer Immunotherapy
Current Medicinal ChemistryAbstract: Immune checkpoint inhibitors (ICIs) have shown unprecedented efficacy in treating many advanced cancers. Although FDA-approved ICIs have shown promising efficacy in treating many advanced cancers, their application is greatly limited by the low response rate, immune-related adverse events (irAE), and drug resistance.
Yeteng Mu, Xingang Guan
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CD155 Is a Potential Biomarker in Basal Cell Carcinoma
The American Journal of Dermatopathology, 2023Jesús Iván, Martínez-Ortega +2 more
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TRANSLATIONAL OPPORTUNITIES FOR ANTIBODIES TARGETING PVR (CD155)
2022Poliovirus receptor (PVR/CD155), expressed by many types of cancer cells, has been gaining considerable scientific interest because of its intrinsic and extrinsic roles in tumor progression. The intrinsic functions of PVR in tumor cells promote tumor progression and metastasis, whereas its extrinsic functions involve interaction with immune cell ...
Hiršl, Lea +2 more
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Downregulation of CD155 (PVR) by mouse cytomegalovirus
2011NK cells are equipped with a collection of activating and inhibitory receptors and thus, the NK activation status depends on the summation of their activating and inhibitory signals. Human CD155 (polio virus receptor, PVR), which is expressed by numerous tumors and healthy cells, is recognized by three different receptors: two co-stimulating receptors (
Babić Čač, Marina +1 more
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