Results 111 to 120 of about 113,104 (262)
Blinatumomab bridges the gap between leukemia and immunity
OncoImmunology, 2017 Takahiro Yamazaki, Lorenzo Galluzzi
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CD19: a promising target for systemic sclerosis
Frontiers in ImmunologySystemic sclerosis (SSc) is an autoimmune disease characterized by immune dysregulation, vascular damage, and fibrosis. B cells play a significant role in SSc through autoantibody production, cytokine secretion, and T cell regulation. Autoantibodies like anti-topoisomerase I and anti-RNA polymerase III are specific to SSc and linked to clinical ...
openaire +3 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse +4 more
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Comparison of Tissue Preparations to Identify and Phenotype T Cells in Human Colorectal Tumor Tissue
Cytometry Part A, EarlyView.ABSTRACT Archived patient samples (e.g., formalin‐fixed paraffin embedded (FFPE) tissue blocks, cryoembedded tissue blocks, and frozen whole tissue samples) are a source of immune information for which corresponding patient data is often collected.
Justin F. Tirados +5 more
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Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
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Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
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Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Flow cytometry is an essential component of routine hematological lab testing. Many computational methods have been proposed for the analysis of flow cytometry data, but most have focused on supervised learning for just one or a few specific disorders.
Brendan O'Fallon +4 more
wiley +1 more source
HaematologicaCAR-T cell therapy has revolutionized the treatment of hematologic malignancies. Nevertheless, significant challenges remain, particularly concerning its severe adverse effects. Extracellular vesicles (EVs) emerged as promising therapeutic agents due to
P. Lanuti +33 more
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