Results 151 to 160 of about 98,309 (302)

P106 | Cd20 positive multiple myeloma: is it a different entity?

Haematologica
Introduction. Expression of CD20 antigen is generally negative in patients (pts) with multiple myeloma (MM). However, a small number of MM pts (15-20%) can show CD20 positivity on neoplastic plasma cells (PC).
Monica Poscente
doaj  

CD20; CD47 [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Tumor Invasive Border Index (TIBI) in colorectal cancer: linking infiltrative morphology to molecular insights

The Journal of Pathology, EarlyView.
Abstract Tumor border configuration influences colorectal cancer (CRC) prognosis, yet its molecular determinants remain unclear and existing assessment criteria have faced challenges with reproducibility. We introduce the Tumor Invasive Border Index (TIBI), a novel and reproducible method that quantifies the proportion of tumor stroma and adipose ...
Akseli Kehusmaa, Jouni Härkönen, Huayi Li, Päivi Sirniö, Ville K Äijälä, Henna Karjalainen, Meeri Kastinen, Vilja V Tapiainen, Tuomo Mantere, Vesa‐Matti Pohjanen, Hanna Elomaa, Onni Sirkiä, Nicolas Pasquier, Maarit Ahtiainen, Olli Helminen, Erkki‐Ville Wirta, Taneli T Mattila, Outi Lindgren, Janette Savela, Jukka Rintala, Sanna Meriläinen, Juha Saarnio, Tero Rautio, Toni T Seppälä, Jan Böhm, Jukka‐Pekka Mecklin, Markus J Mäkinen, Anne Tuomisto, Johanna Ivaska, Juha P Väyrynen   +29 more
wiley   +1 more source

CD20 Positive [PDF]

, 2020
openaire   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Lymph node microenvironment remodeling unlocks local antibody-mediated B cell depletion. [PDF]

Sci Adv
Garcia Z, Bardou M, Loap A, Feldmann LC, Godon O, Guerin MV, Lemaître F, Macdonald LE, Bruhns P, Serafini N, Bousso P, Grandjean CL.   +11 more
europepmc   +1 more source

CD20 Negative [PDF]

, 2020
openaire   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

The Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato, Kazuki Miura, Juki Nakao, Hiroyuki Nakamura   +3 more
wiley   +1 more source

Revisiting the Ofatumumab Epitope on CD20 through Integrative Molecular Dynamics and Flow Cytometry Analyses. [PDF]

Comput Struct Biotechnol J
Guimarães AVF, Barbosa JSS, Lima AJF, Bezerra MRL, Pinheiro DP, Pontes LQ, Furtado GP, Lourenzoni MR.   +7 more
europepmc   +1 more source

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

VIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen, Youdong Liu, Hongda Pan, Tianyi Cai, Mingde Zang, Xiaowen Liu, Ziwen Long, Xin Fan, Jun Lu, Fenglin Liu   +9 more
wiley   +1 more source