Results 131 to 140 of about 733 (164)

Advancement in the Antigenic Epitopes and Vaccine Adjuvants of African Swine Fever Virus. [PDF]

open access: yesPathogens
Wu Q   +11 more
europepmc   +1 more source

Baculovirus-Displayed ASFV Epitope-Composite Protein Elicits Potent Immune Responses. [PDF]

open access: yesMicroorganisms
Zhang W   +11 more
europepmc   +1 more source

Development and characterization of recombinant ASFV CD2v protein nanoparticle-induced monoclonal antibody

International Journal of Biological Macromolecules, 2022
African swine fever (ASF) caused by African swine fever virus (ASFV) is becoming a serious threat to the swine industry worldwide. CD2v is a key pathogenic factor of ASFV and the protective antigen with low immunogenicity, whereas viral protein-based nanoparticles have advantages of precise assembly and high immunogenicity.
Dongna, Ren   +8 more
openaire   +2 more sources

Structure and functional analysis of the African Swine Fever virus encoded CD2v/EP402R protein and investigation of its role in virus persistence in pigs

2022
African swine fever is a viral haemorrhagic disease of domestic pigs and wild boar and is a serious threat to the economy of many countries. No vaccines are available to induce protection in pigs against this lethal disease. The most promising approach for vaccine development is the use of modified live attenuated vaccines (MLAV) and these can confer ...
openaire   +1 more source

Development of a subunit vaccine against virus of african svine virus based on cd2v protein with immunoinformatics and molecular dynamics methods

Kristallografiâ
A subunit vaccine against the African swine fever virus (ASF) has been designed using immunoinformatics and molecular dynamics methods. The three-dimensional structure of the selected immunogenic protein of the ASF-CD2v virus was modelled, and its topology relative to the membrane was predicted. B- and T-cell epitopes for the supramembrane part of CD2v
A. S. Ivanovsky   +7 more
openaire   +1 more source

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