Results 51 to 60 of about 733 (164)

Growth Kinetics and Protective Efficacy of Attenuated ASFV Strain Congo with Deletion of the EP402 Gene

open access: yesViruses, 2021
African swine fever (ASF) is an emerging disease threat to the swine industry worldwide. There is no vaccine against ASF, and progress is hindered by a lack of knowledge concerning the extent of ASFV strain diversity and the viral antigens conferring ...
Galina Koltsova   +5 more
doaj   +1 more source

The CD2v protein enhances African swine fever virus replication in the tick vector, Ornithodoros erraticus

open access: yesVirology, 2009
The NH/P68 non-haemadsorbing (non-HAD) African swine fever virus (ASFV) isolate contains frameshift mutations in the EP402R and adjacent EP153R genes. These encode, respectively, the protein (CD2v) that is required for the haemadsorption (HAD) of swine erythrocytes to ASFV-infected cells and a C-type lectin protein.
Rowlands, Rebecca J.   +4 more
openaire   +2 more sources

A Robust Quadruple Protein-Based Indirect ELISA for Detection of Antibodies to African Swine Fever Virus in Pigs

open access: yesMicroorganisms, 2023
African swine fever (ASF) emerged in domestic pigs and wild boars in China in 2018 and rapidly spread to neighboring Asian countries. Currently, no effective vaccine or diagnostic tests are available to prevent its spread. We developed a robust quadruple
Min-Chul Jung   +14 more
doaj   +1 more source

Live Attenuated African Swine Fever Viruses as Ideal Tools to Dissect the Mechanisms Involved in Cross-Protection [PDF]

open access: yes, 2020
African swine fever (ASF) has become the major threat for the global swine industry. Furthermore, the epidemiological situation of African swine fever virus (ASFV) in some endemic regions of Sub-Saharan Africa is worse than ever, with multiple virus ...
Accensi, Francesc   +11 more
core   +1 more source

Mucosal and cellular immune responses elicited by nasal and intramuscular inoculation with ASFV candidate immunogens

open access: yesFrontiers in Immunology, 2023
African swine fever (ASF) is an infectious disease caused by African swine fever virus (ASFV) that is highly contagious and has an extremely high mortality rate (infected by virulent strains) among domestic and wild pigs, causing huge economic losses to ...
Lulu Xu   +35 more
doaj   +1 more source

Molecular characterization of African swine fever viruses from Burkina Faso, 2018

open access: yesBMC Veterinary Research, 2022
Background African swine fever (ASF) is a viral hemorrhagic disease of domestic and wild swine. ASF has been endemic in Burkina Faso since 2003. In October 2018, substantial pig deaths occurred in Ouagadougou and two neighboring municipalities in central
Moctar Sidi   +14 more
doaj   +1 more source

Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization [PDF]

open access: yes, 2016
: Antibodies are essential for structural determinations and functional studies of membrane proteins, but antibody generation is limited by the availability of properly-folded and purified antigen.

core   +1 more source

Immunization of Pigs with Recombinant Plasmids Containing Genes of Ubiquitinated p30, p54 and CD2v Proteins of African Swine Fever Virus

open access: yesActa Veterinaria, 2020
Abstract Three recombinant plasmid constructs, expressing chimeric proteins containing human ubiquitin fused to an ectodomain of one of the potentially protective proteins (p30, p54 and CD2v) of the attenuated MK-200 strain of African swine fever virus (ASFV), were created as potential inductors of specific antiviral cellular immunity ...
Imatdinov, Almaz R.   +7 more
openaire   +3 more sources

Genetic characterisation of six novel African swine fever viruses isolated from a pig, warthog, wild boar, and ticks [PDF]

open access: yes, 2021
African swine fever (ASF) is a disease that affects domestic pigs and wild boars, resulting in up to 100% case fatality rate, and there is currently no effective treatment or vaccine.
Ndlovu, Sandy Sibusiso
core   +1 more source

Screening and identification of the dominant antigens of the African swine fever virus [PDF]

open access: yes, 2023
African swine fever is a highly lethal contagious disease of pigs for which there is no vaccine. Its causative agent African swine fever virus (ASFV) is a highly complex enveloped DNA virus encoding more than 150 open reading frames.
Ancheng Wang   +18 more
core   +1 more source

Home - About - Disclaimer - Privacy