Results 231 to 240 of about 287,679 (291)

High CD3+ and CD34+ peripheral blood stem cell grafts content is associated with increased risk of graft-versus-host disease without beneficial effect on disease control after reduced-intensity conditioning allogeneic transplantation from matched unrelated donors for acute myeloid leukemia — an analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

open access: diamond, 2016
Tomasz Czerw   +17 more
openalex   +2 more sources

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

open access: yesSmall Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto   +12 more
wiley   +1 more source

Prostatic stromal tumors with uncertain malignant potential: A scoping review of clinical challenges and management strategies

open access: yesUroPrecision, EarlyView.
Abstract Prostatic stromal tumor of uncertain malignant potential (STUMP) is a rare neoplasm arising from specialized prostatic stromal cells with a broad range of histologic patterns and unpredictable clinical behavior. It is often challenging to distinguish STUMP from prostatic stromal sarcoma due to morphological similarities, necessitating specific
Ibrahim A. Khalil   +7 more
wiley   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

open access: yesVIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang   +22 more
wiley   +1 more source

Efficacy of Repeated Administration of Cultured Human CD34<sup>+</sup> Cells Against Streptozotocin-Induced Diabetic Nephropathy in Rats. [PDF]

open access: yesCells
Ohtake T   +10 more
europepmc   +1 more source

Attenuating spinal cord injury by conditioned medium from human umbilical cord blood-derived CD34+ cells in rats

open access: diamond, 2016
Chia-Hong Yeng   +7 more
openalex   +1 more source

Application of 23Na MRI at 7 Tesla in distinguishing IDH genotype, P53 phenotype, and Ki‐67 LI in adult‐type diffuse gliomas

open access: yesVIEW, EarlyView.
Notes: Their molecular characteristics—such as IDH genotype, P53 phenotype, and Ki‐67 labeling index—are critical determinants of treatment strategies and prognosis for patients of adult‐type diffuse gliomas. In this study, we employed 7‐tesla sodium magnetic resonance imaging (23Na MRI) and demonstrated that total sodium concentration (TSC) and ...
Letian Yuan   +9 more
wiley   +1 more source

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