Results 271 to 280 of about 287,679 (291)

Acral Mesenchymal Spindle Cell Neoplasm With a Novel HMGA2::NCOA2 Fusion

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Molecular profiling has revolutionized the field of soft tissue pathology, enhancing diagnostic precision and treatment strategies. The integration of molecular analysis and immunohistochemistry has been crucial for classifying diagnostically challenging acral mesenchymal neoplasms.
Grace Z. Armstrong   +5 more
wiley   +1 more source

Loss of FBXO11 establishes a stem cell program in acute myeloid leukemia by dysregulating LONP1. [PDF]

open access: yesJ Clin Invest
Kincross H   +24 more
europepmc   +1 more source

Atypical Fibroxanthoma/Pleomorphic Dermal Sarcoma With Osseous Metaplasia: A Series of Three Cases

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare mesenchymal tumors typically arising on sun‐damaged skin of the head and neck in elderly patients. PDS is a more aggressive tumor but with similar demographics, cellular morphology, immunohistochemical features, and genetic findings.
Taylor Novice   +3 more
wiley   +1 more source

Case Report: autologous stem cell boost enables hematopoietic recovery after severe cytopenia induced by BCMA-targeted bispecific antibody therapy in multiple myeloma. [PDF]

open access: yesFront Oncol
Akiyama H   +12 more
europepmc   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Rare Presentation of Gastric Myeloid Sarcoma. [PDF]

open access: yesACG Case Rep J
Jain S, Dickerson A, Moparty B, Kale H.
europepmc   +1 more source

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson   +12 more
wiley   +1 more source

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