Results 91 to 100 of about 5,353 (192)

Supplementary Table 6 from Identification of Campath-1 (CD52) as Novel Drug Target in Neoplastic Stem Cells in 5q-Patients with MDS and AML

, 2014
PDF file - 83K, Supplementary Table S6: Expression of CD52, CD123 and CLL-1 on CD34+/CD38−/CD90+/CD45RA− cells in patients with MDS and on CD34+/CD38−/CD90−/CD45RA− cells in patients with AML.
Matthias Mayerhofer (186269), Harald Herrmann (186251), Michael Willmann (10514882), Berthold Streubel (607019), Sabine Cerny-Reiterer (469042), Gregor Hoermann (186267), Thomas Rülicke (82172), Susanne Herndlhofer (14988750), Katharina Blatt (186249), Werner Rabitsch (5876585), Wolfgang R. Sperr (4728906), Peter Valent (186285), Irina Sadovnik (11821820)   +12 more
core   +1 more source

Single cell analysis of phosphoinositide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry

Haematologica, 2006
BACKGROUND AND OBJECTIVES: Abnormal activation of several signal transduction pathways such as phosphoinositide 3-kinase (PI3K) and MAP kinases has been reported in acute myeloid leukemia (AML).
V Bardet, J Tamburini, N Ifrah, F Dreyfus, P Mayeux, D Bouscary, C Lacombe   +6 more
doaj  

NUC-7738 regulates β-catenin signalling resulting in reduced proliferation and self-renewal of AML cells

PLoS ONE, 2022
Acute myeloid leukemia (AML) stem cells are required for the initiation and maintenance of the disease. Activation of the Wnt/β-catenin pathway is required for the survival and development of AML leukaemia stem cells (LSCs) and therefore, targeting β ...
Akbar Muhammed Shahid, In Hwa Um, Mustafa Elshani, Ying Zhang, David James Harrison   +4 more
doaj  

ANALYTICAL VALIDATION OF A 10-COLOR FLOW CYTOMETRY PANEL FOR ASSESSMENT OF MEASURABLE RESIDUAL DISEASE OF ACUTE MYELOID LEUKEMIA

Hematology, Transfusion and Cell Therapy
The assessment of measurable residual disease (MRD) in acute myeloid leukemia (AML) by flow cytometry (FC) is challenging and requires full standardization to provide reliable results for patient management.
AR Severino, CM Bertolucci, JFDS Tosi, MRV Ikoma-Colturato   +3 more
doaj   +1 more source

NG2 MOLECULE EXPRESSION IN ACUTE LYMPHOBLASTIC LEUKEMIA B CELLS: A FLOW-CYTOMETRIC MARKER FOR THE RAPID IDENTIFICATION OF KMT2A GENE REARRANGEMENTS

Mediterranean Journal of Hematology and Infectious Diseases
Background: B-lineage acute lymphoblastic leukemias (B-ALL) harboring rearrangements of the histone lysine [K]-Methyltransferase 2A (KMT2A) gene on chromosome 11q23 (KMT2A-r), represent a category with dismal prognosis.
Maria Laura Bisegna, Nadia Peragine, Loredana Elia, Mabel Matarazzo, Maria Laura Milani, Stefania Intoppa, Mariangela Di Trani, Francesco Malfona, Maurizio Martelli, Maria Stefania De Propris   +9 more
doaj   +1 more source

Epstein-Barr virus-negative aggressive natural killer-cell leukaemia with high P-glycoprotein activity and phosphorylated extracellular signal-regulated protein kinases 1 and 2

Hematology Reports, 2012
Aggressive natural killer-cell leukaemia (ANKL) is a rare type of disease with fulminant course and poor outcome. The disease is more prevalent among Asians than in other ethnic groups and shows strong association with Epstein-Barr virus (EBV) and P ...
Sanja Perkovic, Sandra Basic-Kinda, Vladimir Gasparovic, Zeljko Krznaric, Jaksa Babel, Ivana Ilic, Igor Aurer, Drago Batinic   +7 more
doaj   +1 more source

Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms

Journal of Hematology & Oncology, 2011
A 54-year-old woman was diagnosed with infiltrative ductal breast carcinoma. Two years after treatment, the patient developed an acute myeloid leukemia (AML) which harbored del(11q23) in 8% of the blast cells.
da Silva Dayse A, Lage Claudia, Alves Gilda, da Silva Roberto I, Fernandez Teresa S, Campos Mércia M, Gomes Bernadete E, Orfao Alberto, Ornellas Maria, Diamond Hilda, Moellmann-Coelho Arthur, da Cruz Geydson S, Bouzas Luis, Abdelhay Eliana   +13 more
doaj   +1 more source

Acute Myeloid Leukemia (AML) With T-Cell Differentiation Arising From Chronic Myelomonocytic Leukemia (CMML)

Case Reports in Hematology
Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm characterized by peripheral blood monocytosis and bone marrow dysplasia.
Anthony Crymes, Mark G. Evans, Deepa Jeyakumar, Jerry J. Lou, Xiaohui Zhao, Sherif A. Rezk   +5 more
doaj   +1 more source

Comprehensive profiling of AML and T-cell states across disease stages in acute myeloid leukemia using spectral flow cytometry

Blood Immunology & Cellular Therapy
: Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by clonal expansion of myeloid precursors, yet the interplay between leukemic and immune cells across disease stages remains poorly understood.
Mhd Yousuf Yassouf, Jessica L. Root, Poonam N. Desai, Nicole R. Vaughn, Ferdinandos Skoulidis, Hussein A. Abbas, Patrick K. Reville   +6 more
doaj   +1 more source

Characterization of CD34+ Cells from Patients with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS) Using a t-Distributed Stochastic Neighbor Embedding (t-SNE) Protocol

Using multi-color flow cytometry analysis, we studied the immunophenotypical differences between leukemic cells from patients with AML/MDS and hematopoietic stem and progenitor cells (HSPCs) from patients in complete remission (CR) following their ...
Rainer Haas, Ron P. Cadeddu, Paul S. Jäger, Christian Wimmenauer, Thomas Heinzel, Jörg Timm, Wiebke Moskorz, Cathrin Nollmann   +7 more
core   +1 more source