Results 21 to 30 of about 5,353 (192)

CIRCULATING HEMATOPOIETIC STEM AND PROGENITOR CELLS AND ERYTHROBLASTS COUNTING IS INCREASED IN PATIENTS WITH SICKLE CELL ANEMIA

Hematology, Transfusion and Cell Therapy, 2023
Due to the challenges associated with accessing bone marrow samples from individuals with sickle cell anemia (SCA), hematopoiesis in the context of this disease remains less studied compared to other pathologies.
J Milhomens, A Godard, J Grenier, M De-Grandis, DT Covas, W El-Nemer, S Kashima   +6 more
doaj   +1 more source

IMMUNOPHENOTYPIC COMPARISON BETWEEN REACTIVE BONE MARROW B-LYMPHOCYTE PRECURSOR (HEMATOGONES) AND B-NEOPLASTIC LYMPHOBLAST LEUKAEMIA USING CD 34, CD 123 BY FLOWCYTOMETRY

The Iraqi Journal of Medical Sciences, 2016
Background:Flow cytometric study found that lymphoblasts of B acute lymphoblastic leukemia exhibited multiple aberrant antigens by which they can be distinguished from hematogones. These antigens are CD34 and CD123.
Yousra A. Shallan, Raad J. Musa
doaj   +4 more sources

Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia. [PDF]

, 2017
Purpose: The persistence of leukemia stem cells (LSC)-containing cells after induction therapy may contribute to minimal residual disease (MRD) and relapse in acute myeloid leukemia (AML).
Kantarjian, Hagop, Zhang, Qi, DiPersio, John, Han, Lina, Nogueras González, Graciela, Pan, Rongqing, Huang, Xuelin, Ravandi, Farhad, Konopleva, Marina, Cavazos, Antonio, Ciurea, Stefan, Cortes, Jorge, Jorgensen, Jeffrey, Ai-Atrash, Gheath, Mu, Hong, Wang, Sa, Shi, Ce, Andreeff, Michael, Zhou, Jin, Rettig, Mike, Brooks, Chris   +20 more
core   +1 more source

acute basophilic leukaemia [PDF]

, 2021
Acute basophilic leukaemia (ABL) is a rare subtype of acute myeloid leukaemia (AML); therefore, few data are available about its biology. Herein, we analysed two ABL patients using flow cytometry and next-generation sequencing (NGS). Two cell populations
Tadakazu Kondo, Shindo, Takero, Yasuhito Nannya, Mizuki Watanabe, Kondo, Tadakazu, Watanabe, Mizuki, Ogawa, Seishi, Yamashita, Kouhei, Nannya, Yasuhito, Seishi Ogawa, Takero Shindo, Akifumi Takaori‐Kondo, Shimizu, Takuya, Takaori‐Kondo, Akifumi, Toshio Kitawaki, Kouhei Yamashita, Takuya Shimizu, Hishizawa, Masakatsu, Masakatsu Hishizawa, Kitawaki, Toshio   +19 more
core   +1 more source

RELATIONSHIP BETWEEN THE EXPRESSION OF CD34, CD123 AND MYELOPEROXIDASE MARKERS BY FLOW CYTOMETRY AND RESPONSE TO INDUCTION THERAPY IN ACUTE MYELOID LEUKEMIA

The Iraqi Journal of Medical Sciences, 2016
Background:Different immunophenotypic markers were found to be related to the prognosis of acute myeloid leukemia. Among them are CD34, CD123 and myeloperoxidase.
Faez Sh. Almohsen, Subh S. Al-Mudallal
doaj   +4 more sources

EXPLORING THE EFFICACY OF AZACITIDINE AND VENETOCLAX COMBINATION IN TREATING ACUTE MYELOID LEUKEMIA IN CASES OF RELAPSE FOLLOWING AZACITIDINE TREATMENT AND HIGH-DOSE VITAMINS THERAPY

Hematology, Transfusion and Cell Therapy, 2023
Objective: Report of 4 cases monitored at the do Servidor Publico Estadual Hospital (IAMSPE), SP. Patients considered unfit for 3+7 regimen received AZAVIT-ABCEF (azacytidine, filgrastim, erythropoietin combined with high doses of vitamins B1, C, and D3).
VM Sthel, VLP Figueiredo
doaj   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
Lorin, V, Tangy, Frédéric, Vabret, Astrid, Vidalain, Pierre-Olivier, Tangy, F, Escriou, Nicolas, Millet, J, Escriou, N, Law, H, Albert, ML, Millet, Jean, K., Nal, B, Law, Helen, Albert, Matthew L, Vabret, A, Nal, Béatrice, Lorin, Valérie, Vidalain, PO, Mesel-Lemoine, Mariana   +18 more
core   +1 more source

Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape

Haematologica, 2020
Neoplasms involving plasmacytoid dendritic cells (pDC) include blastic pDC neoplasms (BPDCN) and other pDC proliferations, where pDC are associated with myeloid malignancies: most frequently chronic myelomonocytic leukemia (CMML) but also acute myeloid ...
Loria Zalmaï, Pierre-Julien Viailly, Sabeha Biichle, Meyling Cheok, Lou Soret, Fanny Angelot-Delettre, Tony Petrella, Marie-Agnès Collonge-Rame, Estelle Seilles, Sandrine Geffroy, Eric Deconinck, Etienne Daguindau, Sabrina Bouyer, Elodie Dindinaud, Victor Baunin, Magali Le Garff-Tavernier, Damien Roos-Weil, Orianne Wagner-Ballon, Véronique Salaun, Jean Feuillard, Sophie Brun, Bernard Drenou, Caroline Mayeur-Rousse, Patricia Okamba, Véronique Dorvaux, Michel Tichionni, Johann Rose, Marie Thérèse Rubio, Marie Christine Jacob, Victoria Raggueneau, Claude Preudhomme, Philippe Saas, Christophe Ferrand, Olivier Adotevi, Christophe Roumier, Fabrice Jardin, Francine Garnache-Ottou, Florian Renosi   +37 more
doaj   +1 more source

CD123 target validation and preclinical evaluation of ADCC activity of anti-CD123 antibody CSL362 in combination with NKs from AML patients in remission

, 2017
Despite the heterogeneity of acute myeloid leukemia (AML), overexpression of the interleukin-3 receptor-α (CD123) on both the more differentiated leukemic blast and leukemic stem cells (LSCs) provides a therapeutic target for antibody treatment.
L H Xie, M D Minden, S J Busfield, M Biondo, A Arruda, G Vairo, X Yang   +6 more
core   +2 more sources

Graft immune cell composition associates with clinical outcome of allogeneic hematopoietic stem cell transplantation in patients with AML

Frontiers in Immunology, 2016
Complications of allogeneic hematopoietic stem cell transplantation (HSCT) have been attributed to immune cells transferred into the patient with the graft. However, a detailed immune cell composition of the graft is usually not evaluated. In the present
Ulla Impola, Antti Larjo, Urpu Salmenniemi, Mervi Putkonen, Maija Itälä-Remes, Jukka Partanen   +5 more
doaj   +1 more source