Results 11 to 20 of about 53,340 (302)

CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice [PDF]

Journal of Lipid Research, 2003
CD36 (fatty acid translocase) is involved in high-affinity peripheral fatty acid uptake. Mice lacking CD36 exhibit increased plasma free fatty acid and triglyceride (TG) levels and decreased glucose levels.
Jeltje R. Goudriaan, Vivian E.H. Dahlmans, Bas Teusink, D. Margriet Ouwens, Maria Febbraio, J. Anton Maassen, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol   +8 more
doaj   +2 more sources

CD36 and Its Role in Obesity

Obesity Reviews
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator
Nahuel Garcia, Maiken Mellergaard, Carlos Salomon, Pilar Sepulveda, Peter Kristensen, Aase Handberg   +5 more
openaire   +7 more sources

Comparative Studies of Vertebrate Platelet Glycoprotein 4 (CD36) [PDF]

Biomolecules, 2012
Platelet glycoprotein 4 (CD36) (or fatty acyl translocase [FAT], or scavenger receptor class B, member 3 [SCARB3]) is an essential cell surface and skeletal muscle outer mitochondrial membrane glycoprotein involved in multiple functions in the body. CD36
Roger S. Holmes
doaj   +2 more sources

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8⁺ T Cells by Inhibiting S100A8/A9-CD36 Axis in Obesity-Associated Pancreatic Adenocarcinoma. [PDF]

Adv Sci (Weinh)
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Chen K, Chen R, Li W, Song B, Zhang R, Dai L, Qi Y, Chen R, Xu Y, Li H, Huang J, Wu F, Peng J, Wang X, Xiong Y, Mu C, Cheng G, Li Z, Ruan S, Huang L, Gu M.   +20 more
europepmc   +2 more sources

CD36 is a receptor for human sapovirus. [PDF]

Sci Adv
Human sapovirus (HuSaV) is a major cause of gastroenteritis but has long lacked a defined receptor. Here, we identify the scavenger receptor CD36 as essential for infection.
Haga K, Arai M, Takai-Todaka R, Fukuda Y, Ishiyama R, Katayama K.   +5 more
europepmc   +2 more sources

Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes. [PDF]

, 2009
The prevalence of CD36 deficiency in East Asian and African populations suggests that the causal variants are under selection by severe malaria. Previous analysis of data from the International HapMap Project indicated that a CD36 haplotype bearing a ...
Jallow, Muminatou, Palma, Alejandro, Jeffreys, Anna E, Michael J. Griffiths, Fry, Andrew Evan, Teo, Yik Y, Taylor, Terrie E., Kerrin S. Small, Fry, A. E., Fry, Andrew E., Williams, T. N., Diakite, M, Palma, A., Oduro, Abraham R., Newton, C. R., Kwiatkowski, DP, Anna E. Jeffreys, Pinder, M., Jeffreys, AE, Kwadwo A. Koram, Fry, AE, Kwiatkowski, Dominic, Sisay-Joof, Fatou, Williams, Thomas N., Kirk A. Rockett, Clark, Taane G., Wilson, Jonathan, Rockett, KA, Koram, KA, Abraham R. Oduro, Dominic P. Kwiatkowski, Mahamadou Diakite, Yik Y. Teo, Ghansa, A., Jeffreys, A. E., Kwiatkowski, Dominic P., Campino, S, Anita Ghansa, Taane G. Clark, Koram, Kwadwo, Clark, Taane G, Clark, TG, Malcolm E. Molyneux, Molyneux, Malcolm E, Thomas N. Williams, Ghansa, Anita, Green, Angela, Kevin Marsh, Griffiths, Michael J., Small, Kerrin S, Fatou Sisay-Joof, Pinder, M, Taylor, T. E., Clark, T. G., Susana Campino, Auburn, S., Norbert Peshu, Sarah Auburn, Pardis C. Sabeti, Diakite, Mahamadou, Rockett, Kirk A, Sabeti, PC, Rogers, WO, Oduro, Abraham R, Molyneux, Malcolm E., Jallow, M, Marsh, K, Teo, Yik Y., Small, K. S., Campino, S., Rogers, W. O., Green, A., Koram, Kwadwo A., Marsh, Kevin, Pinder, Margaret, Small, Kerrin S., Angela Green, Oduro, AR, Andrew E. Fry, Teo, YY, Teoh, Yin Yoong Jimmy, Kwiatkowski, D. P., Palma, A, Jonathan Wilson, Peshu, N, Alejandro Palma, Williams, TN, Taylor, Terrie E, Griffiths, M. J., Rockett, K. A., Green, A, William O. Rogers, Terrie E. Taylor, Koram, K. A., Sabeti, Pardis C., Sisay-Joof, F, Newton, Charles R., Teo, Y. Y., Molyneux, ME, Rogers, William O, Oduro, A. R., Peshu, N., Rockett, Kirk A., Jeffreys, Anna E., Auburn, Sarah, Diakite, M., Wilson, J., Auburn, S, Koram, Kwadwo A, Griffiths, MJ, Griffiths, Michael J, Newton, Charles R, Muminatou Jallow, Fry, Andrew E, Small, KS, Newton, CR, Jallow, M., Peshu, Norbert, Campino, Susana, Sabeti, Pardis, Sabeti, P. C., Sisay-Joof, F., Williams, Thomas N, Rogers, William O., Taylor, TE, Wilson, J, Charles R. Newton, Ghansa, A, Margaret Pinder, Williams, Thomas, Sabeti, Pardis C, Kwiatkowski, Dominic P   +131 more
core   +1 more source

CD36 is important for adipocyte recruitment and affects lipolysis [PDF]

, 2013
Item does not contain fulltextOBJECTIVE: The scavenger receptor CD36 facilitates the cellular uptake of long-chain fatty acids. As CD36-deficiency attenuates the development of high fat diet (HFD)-induced obesity, the role of CD36-deficiency in ...
Glatz, Jan F. C., Sjoerd A.A. van den Berg, Irene O.C.M. Vroegrijk, van Klinken, Jan Bert, van den Berg, Sjoerd A. A., Steinbusch, L.K., Dijk, K.W. van, Vroegrijk, Irene O. C. M., Havekes, Louis M., Steinbusch, L.K.M., van Harmelen, Vanessa, Harmelen, V. van, Havekes, L.M., Febbraio, Maria, Voshol, Peter J., Jan F.C. Glatz, Glatz, J.F., Berg, S.A.A. van den, Rensen, Patrick C. N., Vanessa van Harmelen, Febbraio, M., van Dijk, Ko Willems, Laura K.M. Steinbusch, Louis M. Havekes, Patrick C.N. Rensen, Maria Febbraio, van Diepen, Janna A., Steinbusch, Laura K. M., Voshol, P.J., Klinken, J.B. van, Rensen, P.C.N., Berg, S.A. van den, Rensen, P.C., Diepen, J.A. van, Glatz, J.F.C., Jan Bert van Klinken, Janna A. van Diepen, Peter J. Voshol, Ko Willems van Dijk, Vroegrijk, I.O.C.M., Vroegrijk, I.O.   +40 more
core   +3 more sources

CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance [PDF]

, 2005
CD36 is involved in high-affinity peripheral FFA uptake. CD36-deficient (cd36-/-) mice exhibit increased plasma FFA and triglyceride (TG) levels. The aim of the present study was to elucidate the cause of the increased plasma TG levels in cd36-/- mice ...
Romijn, Johannes A., Romijn, J A, Havekes, Louis M., oer, M.A.M. den, Febbraio, M, Havekes, L.M., Febbraio, Maria, Voshol, Peter J., Rensen, Patrick C. N., Febbraio, M., Goudriaan, J R, Kuipers, F., Goudriaan, J.R., Goudriaan, Jeltje R., Voshol, P.J., Voshol, P J, Kuipers, F, Romijn, J.A., Rensen, P.C.N., Havekes, L M, Kuipers, F; id_orcid, Kuipers, Folkert, Rensen, P C N, den Boer, Marion A. M., den Boer, M A M   +24 more
core   +1 more source

Cluster of differentiation 36 gene polymorphism (rs1761667) is associated with dietary MUFA intake and hypertension in a Japanese population [PDF]

, 2019
Cluster of differentiation 36 (CD36) is a membrane receptor expressed on a wide variety of human cells. CD36 polymorphisms are reportedly associated with oral fat perception, dietary intake and metabolic disorders. The present study examined associations
Hamajima, Nobuyuki, Imaeda, Nahomi, Fujii, Ryosuke, Hishida, Asahi, Wakai, Kenji, Kondo, Takaaki, Goto, Chiho, Suzuki, Koji   +7 more
core   +1 more source

CD36-ir at cardiomyocyte intercalated discs was significantly increased by PPARγ activation.

, 2020
(A-C) Photomicrographs of left ventricle cardiomyocytes immunostained for CD36 in the (A) control, (B) 6-OHDA + placebo, and (C) 6-OHDA + pioglitazone groups. Scale bar = 50 μm. Arrowheads point to CD36-ir at intercalated discs.
Viktoriya Bondarenko (319083), Marina E. Emborg (8259915), Colleen F. Moore (3229434), Rachel A. Fleddermann (8259909), Heather A. Simmons (8259912), Jeanette M. Metzger (8259900), Helen N. Matsoff (8259903), Alexandra D. Zinnen (8259906), Andres Mejia (4379644)   +8 more
core   +1 more source