Results 21 to 30 of about 53,340 (302)

CD36 maintains the gastric mucosa and associates with gastric disease. [PDF]

, 2021
The gastric epithelium is often exposed to injurious elements and failure of appropriate healing predisposes to ulcers, hemorrhage, and ultimately cancer. We examined the gastric function of CD36, a protein linked to disease and homeostasis.
Varro, Andrea, Latisha Love-Gregory, Pietka, Kathryn M, Mills, Jason C, Narendran, Ramkumar, Ramkumar Narendran, Eric R. Gamazon, Zhi-Feng Miao, Terri Pietka, Love-Gregory, Latisha, Kuda, Ondrej, Lo, Hei-Yong G, Pietka, Terri, Goldenring, James R, James R. Goldenring, Morris, Edward F, Abumrad, Nada A, Miriam Jacome-Sosa, Dmitri Samovski, Jason C. Mills, Peche, Vivek S, Samovski, Dmitri, Edward F. Morris, Vivek S. Peche, Gamazon, Eric R, Ondrej Kuda, Jacome-Sosa, Miriam, Kathryn M. Pietka, Andrea Varro, Nada A. Abumrad, Miao, Zhi-Feng, Hei-Yong G. Lo   +31 more
core   +9 more sources

Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease [PDF]

, 2014
CD36 has been associated with obesity and diabetes in human liver diseases, however, its role in age-associated nonalcoholic fatty liver disease (NAFLD) is unknown.
Jacobs, Rene L., Tissue Repair, Aparicio-Vergara, Marcela, Kloosterhuis, N.J., Bruin, A. de, LS Pathobiologie, Febbraio, M, Hofker, Marten H., García-Monzón, C, Miquilena-Colina, Maria Eugenia, Sheedfar, F, Hofker, MH, Dyck, JR, Febbraio, M., Aparicio-Vergara, M, Sung, Miranda M. Y., Koonen, Debby P. Y.; id_orcid, Jacobs, René L, Sheedfar, F., de Bruin, Alain, Koonen, Debby P. Y., Koonen, Debby P Y, Dyck, Jason R. B., Jacobs, R.L., Sung, Miranda My, Koonen, D.P., García-Monzón, Carmelo, De Bruin, A, Sung, M.M., Miquilena-Colina, M.E., Vargas-Castrillon, J., Sheedfar, Fareeba, Febbraio, Maria, Garcia-Monzon, C., Kloosterhuis, Niels J., Miquilena-Colina, ME, Sung, MM, Hofker, M.H., Vinciguerra, M, Kloosterhuis, Niels J, Kloosterhuis, NJ, Vinciguerra, Manlio, Dyck, Jason Rb, PB TR, Vargas-Castrillón, J, Hofker, Marten H, Koonen, DP, Dyck, J.R., Jacobs, RL, Aparicio-Vergara, M., Vargas-Castrillón, Javier, Vinciguerra, M., Eugenia Miquilena-Colina, Maria   +52 more
core   +3 more sources

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

The role of CD36 in cardiovascular disease [PDF]

Cardiovascular Research, 2020
Abstract CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty acids, the main metabolic substrate in myocardial tissue.
Hongyang Shu, Yizhong Peng, Weijian Hang, Jiali Nie, Ning Zhou, Dao Wen Wang   +5 more
openaire   +2 more sources

Is fat the sixth taste primary? Evidence and implications [PDF]

, 2015
Explores our tongue\u27s ability to detect fat as a distinct taste similar to our ability to sense sweet, sour, bitter, acid and savory. Abstract Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For
Russell Keast, Andrew Costanzo, Russell SJ Keast   +2 more
core   +1 more source

Tumor stem cells fuse with monocytes to form highly invasive tumor-hybrid cells

OncoImmunology, 2020
The ‘cancer cell fusion’ theory is controversial due to the lack of methods available to identify hybrid cells and to follow the phenomenon in patients.
Luis Augusto Aguirre, Karla Montalbán-Hernández, José Avendaño-Ortiz, Elvira Marín, Roberto Lozano, Víctor Toledano, Laura Sánchez-Maroto, Verónica Terrón, Jaime Valentín, Elisa Pulido, José Carlos Casalvilla, Carolina Rubio, Luke Diekhorst, Fernando Laso-García, Carlos del Fresno, Ana Collazo-Lorduy, Beatriz Jiménez-Munarriz, Paloma Gómez-Campelo, Emilio Llanos-González, María Fernández-Velasco, Carlos Rodríguez-Antolín, Rebeca Pérez de Diego, Ramón Cantero-Cid, Enrique Hernádez-Jimenez, Enrique Álvarez, Rocío Rosas, Blanca dies López-Ayllón, Javier de Castro, Stefanie K. Wculek, Carolina Cubillos-Zapata, Inmaculada Ibáñez de Cáceres, Prudencio Díaz-Agero, María Gutiérrez Fernández, María Paz de Miguel, David Sancho, Leon Schulte, Rosario Perona, Cristóbal Belda-Iniesta, Lisardo Boscá, Eduardo López-Collazo   +39 more
doaj   +1 more source

Variants of CD36 gene and their association with CD36 protein expression in platelets.

Blood transfusion = Trasfusione del sangue, 2014
The relationship between CD36 expression level in platelets and polymorphism of the CD36 gene still needs to be explored. Here, we investigated polymorphisms of the CD36 gene and CD36 expression level in platelets in the Chinese Han population.A total of 477 samples were sequenced for exons 2 to 14 of the CD36 gene using a polymerase chain reaction ...
Xianguo, Xu, Ying, Liu, Xiaozhen, Hong, Shu, Chen, Kairong, Ma, Xiaofei, Lan, Yanling, Ying, Ji, He, Faming, Zhu, Hangjun, Lv   +9 more
openaire   +2 more sources

CD36 deficiency attenuates experimental mycobacterial infection [PDF]

, 2010
Background Members of the CD36 scavenger receptor family have been implicated as sensors of microbial products that mediate phagocytosis and inflammation in response to a broad range of pathogens.
Liles W Conrad, Michael Hawkes, Hawkes, Michael, Kevin C Kain, Diassiti Angelina, Li, Xiaoming, Min-Oo, Gundula, Diassiti, Angelina, Li Xiaoming, Gundula Min-Oo, Constance Finney, Finney Constance, Xiaoming Li, Crockett Maryanne, Hawkes Michael, Liu, Jun, Finney, Constance, Kain, Kevin C, Kain Kevin C, Crockett, Maryanne, Liles, W C, Angelina Diassiti, Jun Liu, Maryanne Crockett, W Conrad Liles, Min-Oo Gundula, Liu Jun   +26 more
core   +2 more sources

Prediction of B cell epitopes of CD36 and preparation of MAP

Zhongguo shuxue zazhi
Objective To analyze the structure of CD36, search the possible B cell epitopes and prepare multi-antigen peptides(MAP) with B cell epitopes, so as to provide a preliminary experimental basis for the preparation of CD36 antibodies using MAP with B cell ...
Jing LIU, Xiuzhang XU, Haoqiang DING, Jing DENG, Jiali WANG, Yangkai CHEN, Wenjie XIA, Xin YE   +7 more
doaj   +1 more source