Results 331 to 340 of about 83,609 (361)
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Phytotherapy Research, 2023
Diabetic cardiomyopathy (DCM), one of the major complications of type 2 diabetes, is a leading cause of heart failure and death in advanced diabetes. Although there is an association between DCM and ferroptosis in cardiomyocytes, the internal mechanism ...
Xin Li +7 more
semanticscholar +1 more source
Diabetic cardiomyopathy (DCM), one of the major complications of type 2 diabetes, is a leading cause of heart failure and death in advanced diabetes. Although there is an association between DCM and ferroptosis in cardiomyocytes, the internal mechanism ...
Xin Li +7 more
semanticscholar +1 more source
CD36 is a sensor of diacylglycerides [PDF]
Nature, 2005 Toll-like receptor 2 (TLR2) is required for the recognition of numerous molecular components of bacteria, fungi and protozoa. The breadth of the ligand repertoire seems unusual, even if one considers that TLR2 may form heteromers with TLRs 1 and 6 (ref. 12), and it is likely that additional proteins serve as adapters for TLR2 activation.
Kasper Hoebe +10 more
openaire +2 more sources
Antioxidants and Redox Signaling, 2022
AIMS Impaired fatty acid oxidation (FAO) in mitochondria of hepatocytes causes lipid accumulation and excessive production of ROS and oxidative damage, as a result leads to nonalcoholic fatty liver disease (NAFLD).
S. Zeng +10 more
semanticscholar +1 more source
AIMS Impaired fatty acid oxidation (FAO) in mitochondria of hepatocytes causes lipid accumulation and excessive production of ROS and oxidative damage, as a result leads to nonalcoholic fatty liver disease (NAFLD).
S. Zeng +10 more
semanticscholar +1 more source
Current Opinion in Lipidology, 2000
CD36 has been associated with diverse normal and pathologic processes. These include scavenger receptor functions (uptake of apoptotic cells and modified lipid), lipid metabolism and fatty acid transport, adhesion, angiogenesis, modulation of inflammation, transforming growth factor-beta activation, atherosclerosis, diabetes and cardiomyopathy ...
Roy L. Silverstein, Maria Febbraio
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CD36 has been associated with diverse normal and pathologic processes. These include scavenger receptor functions (uptake of apoptotic cells and modified lipid), lipid metabolism and fatty acid transport, adhesion, angiogenesis, modulation of inflammation, transforming growth factor-beta activation, atherosclerosis, diabetes and cardiomyopathy ...
Roy L. Silverstein, Maria Febbraio
openaire +3 more sources
Physiology & Behavior, 2011
CD36 is a multifunctional protein homologous to the class B scavenger receptor SR-B1 mainly found in tissues with a sustained lipid metabolism and in several hematopoieic cells. CD36 is thought to be involved in various physiological and pathological processes like angiogenesis, thrombosis, atherogenesis, Alzheimer's disease or malaria.
Martin, Céline +5 more
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CD36 is a multifunctional protein homologous to the class B scavenger receptor SR-B1 mainly found in tissues with a sustained lipid metabolism and in several hematopoieic cells. CD36 is thought to be involved in various physiological and pathological processes like angiogenesis, thrombosis, atherogenesis, Alzheimer's disease or malaria.
Martin, Céline +5 more
openaire +4 more sources
CD36 and macrophages in atherosclerosis
Cardiovascular Research, 2007CD36 is a multi-ligand scavenger receptor present on the surface of a number of cells such as platelets, monocytes/macrophages, endothelial and smooth muscle cells. Monocyte/macrophage CD36 has been shown to play a critical role in the development of atherosclerotic lesions by its capacity to bind and endocytose oxidized low density lipoproteins (OxLDL)
Juliette Martin +5 more
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CD36 as a biomarker of atherosclerosis
Free Radical Biology and Medicine, 2014Atherosclerosis is a chronic inflammatory disorder occurs as a result of mononuclear lymphocyte infiltration to the arterial wall accompanied by smooth muscle cell proliferation and damage in the arterial wall caused by extracellular matrix accumulation.
Betul Karademir +3 more
openaire +2 more sources
Current Opinion in Clinical Nutrition and Metabolic Care, 2012
This review explores the recent literature on the role of CD36 in the taste of fat, eating behavior and obesity risk in rodents and humans.During the last decade, evidence was accumulated supporting the existence of a taste of fat responsible for the spontaneous preference for lipid-rich foods.
Philippe Besnard +1 more
openaire +2 more sources
This review explores the recent literature on the role of CD36 in the taste of fat, eating behavior and obesity risk in rodents and humans.During the last decade, evidence was accumulated supporting the existence of a taste of fat responsible for the spontaneous preference for lipid-rich foods.
Philippe Besnard +1 more
openaire +2 more sources
Laboratory Hematology, 2005
CD36 is a multiligand receptor associated with a broad array of physiological processes and involved in markedly diverse disorders, including atherosclerosis, insulin resistance and diabetes, dyslipidemia, tumor angiogenesis, and host defense against Plasmodium falciparum.
Yimin Ge, M. Tarek Elghetany
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CD36 is a multiligand receptor associated with a broad array of physiological processes and involved in markedly diverse disorders, including atherosclerosis, insulin resistance and diabetes, dyslipidemia, tumor angiogenesis, and host defense against Plasmodium falciparum.
Yimin Ge, M. Tarek Elghetany
openaire +3 more sources
CD36 expression in the brains of SAMP8
Archives of Gerontology and Geriatrics, 2013SAMP8, senescence accelerated mice with age-related deficits in memory and learning, are known to show age-related increases of amyloid precursor protein (APP) and immunopositivity for amyloid-β (Aβ) proteins, and moreover to be under elevated oxidative stress.
Masaki Ueno +9 more
openaire +3 more sources