CD36 in asthma: from a candidate immunometabolic checkpoint to genetic susceptibility. [PDF]
Front ImmunolLi X, Zhang C, Zhao S, Chang X, Tang H.
europepmc +1 more source
The Airway Transcriptome in Type 2 Cytokine Biomarker‐High and ‐Low Severe Asthma
Allergy, Volume 81, Issue 9, Page 3300-3317, September 2026.This study distinguishes severe asthma–related airway transcriptomic changes from the effects of high‐dose ICS. Most dysregulated genes in severe asthma show concordance with corticosteroid responses. Corticosteroid‐resistant T2‐high asthma featured T2‐high and epithelial barrier gene upregulation, while T2‐low asthma featured Th1/IL‐17 signatures. ASM,
Jiashu Shen +19 more
wiley +1 more source
Integrated single-cell transcriptomic and machine-learning analyses identify a CD36-associated macrophage state in diabetic nephropathy. [PDF]
Front ImmunolYang X +5 more
europepmc +1 more source
Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 9, Page 1535-1549, September 2026.Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source
Studies of platelet antibodies at MacKay Memorial Hospital in Taiwan: Methods, case reviews and a possible case of post-transfusion purpura. [PDF]
Vox SangChen-Yu C +4 more
europepmc +1 more source
Pathology International, Volume 76, Issue 9, September 2026.Adipocytes regulate tumor development and progression through both local and systemic mechanisms. Local regulation involves cancer‐associated adipocytes, paracrine signaling, lipid transfer, and modulation of stromal and immune cells, whereas adipokines, inflammatory cytokines, extracellular vesicles, and lipid transfer mediate systemic regulation ...
Shinya Sato
wiley +1 more source
The Involvement of the Small GTPase Rac1 in Insulin Signaling That Regulates Plasma Membrane Translocation of the Fatty Acid Transporter CD36 in Mouse White Adipocytes. [PDF]
Int J Mol SciTakenaka N +4 more
europepmc +1 more source
Reviews in Aquaculture, Volume 18, Issue 4, September 2026.This manuscript systematically elucidates the molecular mechanisms underlying absorption, transport, and metabolism of Astaxanthin in aquatic animals, through the analysis of biological functions, transport proteins, and enzyme metabolism system. Furthermore, it outlines future molecular research strategies for Astaxanthin, providing a theoretical ...
Huakang Peng +12 more
wiley +1 more source
<i>Bacteroides cellulosilyticus</i>-derived 2-hydroxyphenylacetic acid rectifies hepatic lipid homeostasis in MASLD by targeting the PPARγ-CD36 axis. [PDF]
Gut MicrobesChen K +21 more
europepmc +1 more source
Revisiting CD8+ T Cells in Allergy: The Emerging Role of Tc2 Cells
Scandinavian Journal of Immunology, Volume 104, Issue 3, September 2026.Tc2 CD8+ T cells in Type 2 inflammation: induction, tissue adaptation, metabolic programming, and therapeutic implications. Both naïve CD8+ T cells and pre‐committed Tc1 CD8+ T cells can be directed towards a Tc2 phenotype, characterised by secretion of the Type 2 cytokines IL‐4, IL‐5, IL‐9 and IL‐13, which in turn drive eosinophil recruitment, goblet ...
Sabrina de Souza Ferreira +1 more
wiley +1 more source