Results 121 to 130 of about 182,736 (214)

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy, Usamah Sayed, Zarina Nasirova, Quvonch Tursunov, Omer Qutaiba B. Allela, Lara Asim Kzar, Rajashree Panigrahi, Neeraj Bainsal   +7 more
wiley   +1 more source

Microglia and neuroinflammation: An in‐depth analysis from functional diversity to disease mechanisms

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
1. Microglial functions arise from dynamic, context‐dependent programs rather than fixed M1/M2 phenotypes. 2. Inflammatory, interferon‐responsive, phagocytic/lipid‐metabolic and repair‐associated programs coexist across disease stages and brain regions. 3.
Jie Chen, Wangzheqi Zhang, Lizhou Song, Yan Liao, Haoling Zhang, Yiyang Xia, Derong Cui   +6 more
wiley   +1 more source

Functional and Proteomic Profiles of CD3(+) Plasma‐Derived Small Extracellular Vesicles Differentiate Cancer Patients From Healthy Donors

European Journal of Immunology, Volume 56, Issue 9, September 2026.
The graphical abstract illustrates MTEX‐driven reprogramming of CD3(+) T cells in patients with melanoma. ABSTRACT Small extracellular vesicles (sEV) released by T cells play a key role in immune regulation. Immune capture with anti‐CD3 antibodies was used to isolate and study T cell‐derived CD3(+)sEV from the plasma of patients with melanoma (MPs) or ...
Piotr Widlak, Jie Han, Alicja Gluszko, Justyna Mika, Aneta Zebrowska, Sujan Kumar Mondal, Marta Gawin, Yana G. Najjar, Joanna Polańska, Monika Pietrowska, Theresa L. Whiteside   +10 more
wiley   +1 more source

Erythroid Involvement in CD36 Deficiency [PDF]

Objective. The CD36 molecule is expressed in platelets, monocytes, erythroblasts, and other different tissues. There are 2 types of platelet CD36 deficiency; types I and II, associated with the absence and presence of CD36 on monocytes, respectively.
Watanabe, Kenichi, Aizawa, Yoshifusa, Masuko, Masayoshi, Abo, Toru, Fuse, Ichiro, 4826, 4827, 4828, 4829, Takahashi, Masuhiro, 4831, Miyajima, Seiichi, 4832, 4822, Hanawa, Haruo, Toba, Ken, 4823, Sakaue, Minori, 4824, 4825   +19 more
core  

Dietary α‐Mangostin Alleviates Steatotic Liver Phenotypes by Remodeling Gut Microbial Tryptophan Metabolism

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT α‐Mangostin (α‐MA), the major xanthone in mangosteen pericarp, is a food‐derived bioactive compound with potential metabolic benefits. However, whether its beneficial effects are linked to gut microbial metabolism remains unclear. In this study, α‐MA was first chemically characterized and subsequently evaluated in an aged laying hen model ...
Weichen Huang, Yujie Lv, Chaoyue Ge, Shenao Zhan, Xinyu Shen, Lianchi Wu, Xiaoxu Wang, Hongmeng Yuan, Dongyou Yu, Bing Liu   +9 more
wiley   +1 more source

The upregulated scavenger receptor CD36 is associated with the progression of nontarget lesions after stent implantation in atherosclerotic rabbits

, 2018
Ruijian Li,1–3,* Sumei Cui,1–3,* Youshun Xu,4 Junhui Xing,5 Li Xue,1–3 Yuguo Chen1–3 1Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; 2Key Laboratory of Emergency and Critical Care Medicine of Shandong ...
Xing J, Xue L, Chen Y, Li R, Cui S, Xu Y
core  

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, Volume 3, Issue 3, September 2026.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Black phosphorus‐based photothermal disruption of cancer‐associated fibroblast barriers and tumor‐associated macrophage targeting to enhance anti‐PD‐L1 immunotherapy in triple‐negative breast cancer

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan, Shicui Hong, Xinyue Wang, Yanghang Li, Cai Wang, Yaxiao Liu, Ying Chen, Chen Fang, Yifeng Zheng, Shengqi Wang, Juping Zhang, Neng Wang, Zhiyu Wang   +12 more
wiley   +1 more source

Coagulation factor FVII fine-tunes hepatic steatosis by blocking AKT-CD36-mediated fatty acid uptake

NAFLD is considered as a risk factor for cardiovascular and cerebrovascular disease owing to its close association with coagulant disturbances. However, the precise biological functions and mechanisms that connect coagulation factors to NAFLD pathology ...
Quanxin Jiang (18003474), Ning Wang (108353), Sijia Lu (566625), Ying Xu (9172), Yanmei Yuan (15255986), Yao Zhang (134381), Xingxing Liang (12643139), Qiqi Qian (18003478), Xuemei Fan (4480078), Jie Xiong (138164), Junli Liu (240401), Junting Xu (1829149), Chuchu Liu (4740894), Suzhen Chen (344588), Peihui Zhou (18003488), Qian Zhou (125859)   +15 more
core   +1 more source