Results 111 to 120 of about 16,744 (229)

A new transfectant panel cell line‐based MoAb‐independent antigen capture assay system for detection of CD36 antibody

Vox Sanguinis, 2014
Background and ObjectivesCD36 antibody (Ab) causes several disorders: neonatal alloimmune thrombocytopenia, platelet transfusion refractoriness and non‐haemolytic transfusion reactions. However, there is no gold‐standard test for CD36 Ab.Materials and MethodsWe developed a transfectant panel cell line‐based MoAb‐independent antigen capture assay system
E, Amakishi, T, Hayashi, Y, Koh, N, Matsuyama, H, Ishii, H, Matsukura, K, Yasui, F, Hirayama   +7 more
openaire   +3 more sources

Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing [PDF]

, 2013
Gastrointestinal disorders, including chronic constipation, faecal impaction and incontinence, are a major cause of morbidity in the ...
Colyer, Frances, Davies, Heather, Gamage, Prasanna, Ranson, Richard N., Saffrey, M.Jill, Yeoman, Mark   +5 more
core  

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

In Human Dermis, Ultraviolet Radiation Induces Expansion of a CD36+ CD11b+ CD1- Macrophage Subset by Infiltration and Proliferation; CD1+ Langerhans-Like Dendritic Antigen-Presenting Cells are Concomitantly Depleted

Journal of Investigative Dermatology, 1995
Antigen-presenting (APC), suppressor T-cell-inducing macrophages infiltrate both human and murine epidermis after ultraviolet radiation (UVR) exposure. To determine their derivation, we prepared epidermal cell and dermal cell suspensions from human keratome biopsy specimens obtained from nonexposed skin and from UVB-irradiated sites (3 d after four ...
Meunier, Laurent, Bata-Csorgo, Zsuzsanna, Cooper, Kevin D.   +2 more
openaire   +2 more sources

Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice [PDF]

, 2013
Incontinence and sexual dysfunction are often increased in the aged human population. In rats and mice the pattern of micturition and faecal clearance also changes with ageing and is suggestive of bladder and bowel ...
Black, G., Ranson, R. N, Saffrey, M. J., Tsang, H., Zhang, M.   +4 more
core  

Studies of platelet antibodies at MacKay Memorial Hospital in Taiwan: Methods, case reviews and a possible case of post‐transfusion purpura

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Platelet antibody screening and identification are crucial and challenging. MacKay Memorial Hospital has been dedicated to this for nearly four decades. We reviewed our experience with platelet antibody detection methods and prevalence, and presented a possible case of post‐transfusion purpura caused by anti‐CD36 ...
Chiang Chen‐Yu, Chang Hsiao‐Lin, Chan Yung‐Shu, Cheng Wern‐Cherng, Lin Marie   +4 more
wiley   +1 more source

Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

Frontiers in Immunology
An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established allowing us to explore the development of immunity. In this model, ~55% of volunteers who received the challenge reached typhoid diagnosis criteria (TD), while ~45%
Franklin R. Toapanta, Jingping Hu, Kari Ann Shirey, Paula J. Bernal, Myron M. Levine, Myron M. Levine, Thomas C. Darton, Claire S. Waddington, Andrew J. Pollard, Marcelo B. Sztein, Marcelo B. Sztein, Marcelo B. Sztein   +11 more
doaj   +1 more source

Investigating human platelet antigens and antibodies in pregnancy: An 11‐year experience from a Canadian reference laboratory

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Foetal and neonatal alloimmune thrombocytopaenia (FNAIT) is a potentially severe immune‐mediated condition that is believed to be under‐identified in the Canadian population. The Canadian Blood Services National Platelet Immunology Reference Laboratory (NPIRL) serves as a centralized referral laboratory for FNAIT ...
Bryan Tordon, Gwen Clarke, Jacqueline Wong, Ann Peregrin, Akash Gupta   +4 more
wiley   +1 more source

CD13 is a bona-fide marker of bovine pre-adipocytes with potential in cultivated fat applications

npj Science of Food
Despite its significant potential, cultivated fat manufacture remains a relatively inefficient process, as it primarily uses source preparations of animal-derived mesenchymal stem/stromal cells (MSC) that are poorly defined and highly heterogenous in ...
Seungmee Lee, Thomas Thrower, Susanna E. Riley, Cristina L. Esteves, F. Xavier Donadeu   +4 more
doaj   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source