Results 91 to 100 of about 463,708 (346)

Supplementary Table 2 from Increases in Absolute Lymphocytes and Circulating CD4⁺ and CD8⁺ T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab

, 2023
Alexander Martens, Kilian Wistuba‐Hamprecht, Jianda Yuan, Michael A. Postow, Phillip Wong, Mariaelena Capone, Gabriele Madonna, Amir Khammari, Bastian Schilling, Antje Sucker, Dirk Schadendorf, Peter Martus, Brigitte Dréno, Paolo A. Ascierto, Jedd D. Wolchok, Graham Pawelec, Claus Garbe, Benjamin Weide   +17 more
openalex   +2 more sources

Expansion of CD25-Negative Forkhead Box P3-Positive T Cells during HIV and Mycobacterium tuberculosis Infection [PDF]

, 2017
Tuberculosis (TB) and HIV alter the immune system, and coinfected (HIV-TB) individuals usually present deregulations of T-lymphocytic immune response.
Ameri, Diego, Angerami, Matias, Ben, Graciela, Laufer, Natalia Lorna, Perez, Hector, Quiroga, María Florencia, Salomon, Horacio Eduardo, Sued, Omar Gustavo, Suárez, Guadalupe Verónica, Vecchione, María Belén   +9 more
core   +2 more sources

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

The relationship between the systemic inflammatory response, tumour proliferative activity, T-lymphocytic and macrophage infiltration, microvessel density and survival in patients with primary operable breast cancer [PDF]

, 2008
The significance of the inter-relationship between tumour and host local/systemic inflammatory responses in primary operable invasive breast cancer is limited.
A Ciucci, A Lannigan, A-M McNicol, AHS Lee, AHS Lee, AM Al Murri, AM Al Murri, AM Al Murri, AM McNicol, B Uzzan, C Badoual, C O'Sullivan, C Wilson, CD Griffith, CG Lis, D C McMillan, DC McMillan, DC McMillan, DC McMillan, EJ Bromwich, EY Lin, G Zhang, H Trihia, HM Ogmundsdottir, HO Wintzer, I Laursen, J Bell, J C Doughty, J Galon, J Vakkila, JA Anderson, JA Soreide, JL Yu, K Canna, KV Albuquerque, LM Coussens, LM Forrest, M Hilmy, M Retsky, M Toi, MC Haffner, MP Margarson, N Jonjic, P Goldwasser, P Reizenstein, PA McArdle, RD Leek, S Hansen, S Hansen, S Tsutsui, S Vgenopoulou, SM Pupa, SM Veronese, T Scholzen, TH Stewart, V Carstairs, Y Zhou   +56 more
core   +2 more sources

Supplementary Figure 2 from Increases in Absolute Lymphocytes and Circulating CD4⁺ and CD8⁺ T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab

, 2023
Alexander Martens, Kilian Wistuba‐Hamprecht, Jianda Yuan, Michael A. Postow, Phillip Wong, Mariaelena Capone, Gabriele Madonna, Amir Khammari, Bastian Schilling, Antje Sucker, Dirk Schadendorf, Peter Martus, Brigitte Dréno, Paolo A. Ascierto, Jedd D. Wolchok, Graham Pawelec, Claus Garbe, Benjamin Weide   +17 more
openalex   +2 more sources

A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions

Advanced Healthcare Materials, EarlyView.
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan, Partho Protim Adhikary, Dana Wörz, Sarah Hedtrich   +3 more
wiley   +1 more source

Decrease in CD4 and CD8 lymphocytes are predictors of severe clinical picture and unfavorable outcome of the disease in patients with COVID-19

Open Medicine
The main objective of this study was to investigate the association between CD4+ and CD8+ lymphocyte values and disease severity, need for oxygen therapy and disease outcomes.
Jovičić Biljana Popovska, Raković Ivana, Đorđević Nemanja, Gavrilović Jagoda, Čanović Predrag, Marjanović Ružica Radojević, Petrović Sara, Milosavljević Katarina B., Divjak Ana, Stanković Nenad, Paunović Milan, Milosavljević Miloš Z.   +11 more
doaj   +1 more source

Regulatory T-lymphocyte subsets in patients with HIV-infection receiving highly active antiretroviral therapy

Бюллетень сибирской медицины, 2019
Background. The reason why HIV-infected patients receiving highly active antiretroviral therapy (HAART) suffer from the increased immune activation remains elusive.
V. A. Chereshnev, E. V. Saidakova, L. B. Korolevskaya, N. G. Shmagel, K. V. Shmagel   +4 more
doaj   +1 more source

Failure in generating hemopoietic stem cells is the primary cause of death from cytomegalovirus disease in the immunocompromised host [PDF]

, 1988
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that CMV infection interferes with the earliest detectable step in hemopoiesis, the generation of the stem cell CFU-S-I, and thereby prevents the ...
Busch, Friedrich W., Bühring, Hans-Jörg, Koszinowski, Ulrich H., Mutter, Wolfgang, Reddehase, Matthias J.   +4 more
core   +2 more sources

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source