Results 191 to 200 of about 831,770 (328)
Fingolimod increases cellular resistance to HIV-1 infection and limits viral reservoir size in peripheral CD4+ T-cells. [PDF]
PLoS PathogMoraga E +12 more
europepmc +1 more source
Disease progression in Human Immunodeficiency Virus type 1 infected viraemic controllers
, 2012 PhDBackground: The mechanism of CD4+ T-cell decline in Human Immunodeficiency Virus-1 (HIV-1) infection is unclear, but the association with plasma HIV-1 RNA-load suggests viral replication is involved.
Groves, Katherine Claire
core
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Successful treatment of refractory primary follicular mucinosis with Tofacitinib. [PDF]
An Bras DermatolLi YL, Fang S.
europepmc +1 more source
Regulatory T cell control of anti-tumour responses
, 2008 One of the main obstacles to immunotherapy of cancer in humans is the immunosuppressive environment that surrounds the tumour mass, preventing any effective immune response from halting or reversing the threat of the tumour. Thus the observations in Balb/
Malcolm, Timothy I.M.
core
Animal Models and Experimental Medicine, EarlyView.This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang +12 more
wiley +2 more sources
The Clonal Conundrum: Clonal CD4⁺ Cutaneous Lymphoid Infiltrate in a Toddler Along a Reactive Primary Cutaneous CD4⁺ Small/Medium T-cell Lymphoproliferative Disorder (PCSM-TCLPD) Spectrum. [PDF]
CureusNaidnur S +4 more
europepmc +1 more source
Animal Models and Experimental Medicine, EarlyView.Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley +1 more source