Results 201 to 210 of about 15,816,019 (291)

Current Perspectives on the Immunopathogenesis and Pathology of Small Ruminant Lentivirus Infections. [PDF]

Viruses
Santana de Cecco B, Tose Kemper R, Ramos Badial P.   +2 more
europepmc   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

MHC-II deficiency in a large Algerian cohort: Clinical, immunological, and genetic characterization. [PDF]

J Hum Immun
Lamara Mahammed L, Belaid B, Chan KW, Mohand-Oussaid A, Drali O, Dehimi A, Leung D, Berkani LM, Sakhri H, Abed A, Tahir M, Merah F, Salmi A, Messadi W, Melzi S, Yang J, Yang XT, Stoddard J, Niemela J, Kenney H, Dahmoune F, Guerrouche F, Mechali A, Saad Djaballah A, Amirat L, Oussalah M, Inouri Y, Dib S, Benbida F, Boubidi C, Titri HI, Sekfali L, Azzouz SM, Laredj A, Bendaoud F, Zerguine H, Hadef D, Kadi A, Elhadef D, Boucenna H, Benallal K, Djalab M, El Mezouar C, Bouhdjila R, Bessahraoui M, Bensaadi N, Mehdid F, Benakli M, Harieche F, Aboura R, Zeroual Z, Smati L, Bendeddouche S, Belbouab R, Mekki A, Bioud B, Ladj SM, Gharnaout M, Ladjouze A, Gacem O, Benhalla N, Rosa Duque JS, Rosenzweig S, Notarangelo LD, Lau YL, Djidjik R.   +65 more
europepmc   +1 more source

Homocitrullinated Peptides Drive Pro‐Inflammatory T Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova, Jaspreet Kaur, Gabrielle Buckley, S. M. Mansour Haeryfar, Lisa Cameron, Ewa Cairns, Lillian Barra   +6 more
wiley   +1 more source

Diagnostic value of CD4, CD8 and CD68 immunohistochemical profiling in EBUS-TBNA samples for differentiating sarcoidosis and tuberculosis. [PDF]

BMC Pulm Med
Özbolat ZB, Ortaköylü MG, Ürer HN, Uysal MA, Bağcı BA, Akalın ES, Parlar MA, İlhan U.   +7 more
europepmc   +1 more source

Cytomegalovirus Esophagitis and Colitis, Esophageal Candidasis and Colon Amebiasis in an HIV Patient with More than 200/.MU.l CD4-positive T Lymphocytes

The Journal of AIDS Research, 2003
YOTSUMOTO, Mihoko, NAKAMURA, Naoshi, KITANO, Kiyoshi, KAMIJYO, Koji, ORII, Kouji, KIYOSAWA, Kendo   +5 more
openaire   +1 more source

Comparative Transcriptional Profiling of Key Macrophage and Fibroblast Subpopulations in Rheumatoid Arthritis–Associated Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib, Ogechukwu Ezenwa, Joshua Sciurba, Eleanor B. Valenzi, John Sembrat, Brittany Cody, Jishnu Das, Robert Lafyatis, Dana P. Ascherman   +8 more
wiley   +1 more source

STING expression in pituitary neuroendocrine tumour immune microenvironments. [PDF]

Endocr Relat Cancer
Loughrey PB, McArdle A, Viratham Pulsawatdi A, McCombe KD, Greene C, James H, Healy EG, Corr F, Ross E, Cooke S, Hunter SJ, Korbonits M, Craig SG, James JA.   +13 more
europepmc   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source