Results 321 to 330 of about 426,320 (349)

CD4-positive T lymphocytes are required for the generation of the primary but not the secondary CD8-positive cytolytic T lymphocyte response to herpes simplex virus in C57BL/6 mice.

Cellular Immunology, 1991
To understand the cellular basis for recovery from HSV infection, it is critical to identify functional interactions between HSV-specific T lymphocyte subpopulations involved in the generation of the optimal response. To this end, the requirement for CD4+ (L3T4+) T lymphocytes in the development of the primary and secondary CD8+ (Lyt-2+) cytolytic T ...
S. Jennings, R. H. Bonneau, Patrick M. Smith, R. Wolcott, R. Chervenak   +4 more
semanticscholar   +4 more sources

Profiles of cytokines produced by CD4-positive T lymphocytes stimulated by anti-CD3 antibody in patients with chronic hepatitis C

Journal of Gastroenterology, 1998
Helper T cells (Th) are classified as type 1 (Th1) and type 2 (Th2) according to the cytokines they produce; interferon-gamma is produced by Th1, and interleukin-4 by Th2. We counted the circulating CD4-positive Th cells that produce interferon-gamma or interleukin-4 with an enzyme-linked immunospot assay.
Koju Kobayashi, M. Ishii, T. Igarashi, T. Satoh, Y. Miyazaki, Y. Yajima, K. Ukai, Hiroshi Suzuki, A. Kanno, Y. Ueno, T. Miura, T. Toyota   +11 more
semanticscholar   +4 more sources

CD4-positive T-lymphocytes can oxidatively modify low density lipoprotein.

Biochemical Society Transactions, 1993
D. Lamb, D. Leake
semanticscholar   +4 more sources

Depletion of CD4-positive T-lymphocytes enhances post-stroke endogenous neurogenesis

Neuroscience Research, 2010
Orie Saino, A. Taguchi, T. Nakagomi, A. Doi, Masashi Takata, S. Kashiwamura, N. Doe, T. Matsuyama   +7 more
semanticscholar   +3 more sources

CD4-POSITIVE AND B LYMPHOCYTES IN TRANSPLANTATION IMMUNITY

Transplantation, 1993
The elimination of CD4+ cells by anti-CD4 antibody caused regression of a malignant solid tumor allograft that does not lose a cytotoxic T lymphocyte-defined target antigen during tumor progression and requires specific CD8+ CTL for tumor rejection. Treatment with anti-CD4 antibody was effective when started 1-2 weeks after tumor challenge and was at ...
Donald A. Rowley, Hans J. Stauss, Hans Schreiber, Hartmut Koeppen, Sunanda Singh, Ben Ho Park   +5 more
openaire   +3 more sources

Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish

Developmental & Comparative Immunology, 2011
The presence of helper and cytotoxic T cells in fish has been suggested, although T cell subsets have yet to be identified at the cellular level. In order to investigate the functions of CD4 and CD8α positive T cells we attempted to produce and characterize monoclonal antibodies (mAbs) against teleost CD4 and CD8α.
Yuzuru Suzuki, Kyosuke Araki, Hideaki Toda, Teruyuki Nakanishi, Takeshi Yabu, Takuhito Koike, Tadaaki Moritomo, Hiroaki Suetake, Yasutaka Saito, Fumio Takizawa, Mitsuru Ototake, Tomonori Somamoto   +11 more
openaire   +3 more sources

Glutathione homeostasis is disturbed in CD4‐positive lymphocytes of HIV‐seropositive individuals

European Journal of Clinical Investigation, 1998
BackgroundNumerous in vitro tests have suggested that a disturbed cellular glutathione homeostasis plays an important role in the pathogenesis of human immunodeficiency virus (HIV) infection.MethodsUsing validated high‐performance liquid chromatography (HPLC) methods, glutathione concentrations were determined in plasma and in cytosol of CD4 ...
Ven, A.J.A.M. van der, Blom, H.J., Peters, W.H.M., Jacobs, L., Verver-Jansen, T.J.G., Koopmans †, P.P., Demacker, P.N.M., Meer, J.W.M. van der   +7 more
openaire   +4 more sources

Recombinant human erythropoietin treatment of chronic renal failure patients normalizes altered phenotype and proliferation of CD4-positive T lymphocytes.

Artificial Organs, 2010
Patients with chronic renal failure (CRF) receive recombinant human erythropoietin (rhEPO) for the correction of anemia. However, rhEPO also has an immunomodulatory effect.
K. Lisowska, A. Dębska-Ślizień, Monika Radzka, J. Witkowski, B. Rutkowski, E. Bryl   +5 more
semanticscholar   +1 more source

LXR activation inhibits chemokine-induced CD4-positive lymphocyte migration

Basic Research in Cardiology, 2010
Migration of CD4-positive lymphocytes into the vessel wall is a critical step in atherogenesis. Recent data suggest that CD4-positive lymphocytes express the nuclear transcription factors Liver-X-Receptor (LXR) alpha and beta with an effect of LXR activators on TH1-cytokine release from these cells.
Dusica Vasic, Angelina Hausauer, Nikolaus Marx, Helga Bach, Daniel Walcher, Philipp Heinz, Vinzenz Hombach, Renate Durst   +7 more
openaire   +3 more sources

The relationship between CD4-positive T-lymphocytes and periodontitis

, 2017
Periodontitis, a chronic inflammatory disease caused by a variety of microbes, causes periodontal tissue damage associated with the host immune response inducing inflammation.
Kunman Li, Jingsha Dai, Jing Ren, Shan Chen, Yan‐bin Chen   +4 more
semanticscholar   +1 more source