Results 331 to 340 of about 426,320 (349)

Proteome database of unsensitized CD4 positive T lymphocytes in T cell receptor transgenic mice

ELECTROPHORESIS, 2003
AbstractWe established a two‐dimensional electrophoresis (2‐DE) mapping database of splenic CD4 T cells prepared from I‐Ad‐restricted ovalbumin (OVA)323‐339 specific T cell receptor (TCR) transgenic mice (OVA23‐3). First we examined the purification of CD4 T cells and found that the high purity of cells produced more accurate protein maps.
Shuichi Kaminogawa, Satoshi Hachimura, Tomohiro Kaji   +2 more
openaire   +3 more sources

Signalling processes involved in C-peptide-induced chemotaxis of CD4-positive lymphocytes

Cellular and Molecular Life Sciences, 2009
Previous data from our group demonstrated that C-peptide induces chemotaxis of CD4-positive lymphocytes in-vitro, mediated by activation of G-protein and PI 3-kinase gamma, but additional signalling pathways involved in this process remained unexplored.
Miriam Grüb, Nikolaus Marx, Milos Aleksic, Helga Bach, K. Giehl, Daniel Walcher, Vinzenz Hombach, Renate Durst   +7 more
openaire   +3 more sources

Expression of CD31 epitopes on human lymphocytes: CD31 monoclonal antibodies differentiate between naive (CD45RA+) and memory (CD45RA-) CD4-positive T cells.

Tissue Antigens, 1991
The CD31 antigen, a member of the immunoglobulin superfamily with a possible cell adhesion function, is expressed on approximately 50% of peripheral blood lymphoid cells at relatively low intensity (10-20% of the level on monocytes).
L. Ashman, G. Aylett
semanticscholar   +1 more source

Expression of Death Receptor 3 (DR3) on Circulating CD4 Positive Lymphocytes in Patients with Alopecia Areata

Benha Journal of Applied Sciences, 2020
Alopecia areata (AA) is an autoimmune disorder characterized by transient hair loss and preservation of the hair follicle that affect both sexes.There is scarcity in the published data that discuss the role of DR3 in pathogenesis and prognosis of AA. Therefore, our study was conducted to study this role by assessment of DR3 expression on circulating
R.H. Abdel Sattar, A.I. Musatafa, N.E. Sorour, Y.F. Lasheen   +3 more
openaire   +2 more sources

Decreases of CD4- and CD8-positive T lymphocytes in retired chromate workers.

American Journal of Industrial Medicine, 1995
To investigate the effects of chromates on the human immune system, we measured total T lymphocytes and their two major subpopulations (CD4+ and CD8+ T lymphocytes) in the peripheral blood of 19 retired male workers who had been exposed to chromate at a ...
T. Tanigawa, S. Araki, T. Araki, N. Minato, K. Yokoyama   +4 more
semanticscholar   +1 more source

A Marked Decrease in CD4-positive Lymphocytes at the Onset of Hepatitis in a Patient With Hepatitis-associated Aplastic Anemia

Journal of Pediatric Hematology/Oncology, 2012
A 10-year-old Japanese boy developed acute hepatitis with high levels of serum Torque teno virus DNA and marked lymphocytopenia, especially CD4 T-lymphocytopenia. Although the total lymphocyte counts rose as the patient recovered from hepatitis, this was largely because of a marked rise in CD8 cells.
Koji Yokoyama, Sachie Nakamura, Yoshifumi Kashii, Shigeru Yotsumoto, Yukiko Oh, Mariko Y. Momoi, Akira Morimoto, Hiroaki Okamoto, Tomomi Hayase, Takahiro Ikeda   +9 more
openaire   +2 more sources

High percentages of CD4-positive lymphocytes harbor the HIV-1 provirus in the blood of certain infected individuals

AIDS, 1993
HIV-1 infection of humans leads to states of immunosuppression. Therefore, we sought to determine precise levels of HIV-1 infection of cells in vivo, as these data may assist in the understanding of the pathogenetic processes involved in HIV infection.We have developed an in situ polymerase chain reaction (IS-PCR), which allows amplification of various
Thikkavarapu Seshamma, Joseph W. Oakes, Roger J. Pomerantz, Omar Bagasra   +3 more
openaire   +3 more sources

Larvicidal properties of macrophages induced by cloned murine schistosomal egg antigen‐specific CD4 positive T‐helper lymphocytes

Parasite Immunology, 1992
Summary The role of T‐helper (TH) lymphocytes in activating peritoneal macrophages (PM) to kill larvae of the helminth Schistosoma mansoni (schistosomula) was investigated with the use of egg antigen‐specific CD4 positive TH clones of both the TH1 and TH2 types.
T. Kanazawa, T S Harris, S M Chikunguwo, Miguel J. Stadecker   +3 more
openaire   +3 more sources

Quantification of CD4-positive T lymphocytes

1995
Abstract Introduction The central lesion in HIV-induced immunodeficiency is the functional and numerical decrease in the CD4-positive population of T lymphocytes. Progressive loss of this key lymphoid population is associated with an increasing range and severity of cellular immunodeficiency and predisposition to ...
openaire   +1 more source

HELPER T LYMPHOCYTE UNRESPONSIVENESS TO CARDIAC ALLOGRAFTS FOLLOWING TRANSIENT DEPLETION OF CD4-POSITIVE CELLS

Transplantation, 1994
Initial treatment of heterotopic cardiac transplant recipients with anti-CD4 mAb promotes long-term (> 60 days) allograft survival. We have used modified limiting dilution analysis to quantitate donor alloantigen-reactive helper T lymphocytes (HTL) and CTL in mice bearing long-term cardiac allografts.
Jane Shelby, R.Douglas Ensley, Sherri Y. Chan, Ernst J. Eichwald, Wenhua Li, D. Keith Bishop   +5 more
openaire   +3 more sources