Results 251 to 260 of about 186,664 (282)

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer. [PDF]

open access: yesInt J Mol Med
Jung E   +14 more
europepmc   +1 more source

Epigenetic maintenance of the injury response state in glioblastoma stem cells. [PDF]

open access: yesNeurooncol Adv
Molaei F   +10 more
europepmc   +1 more source

CD44 in Cancer

Critical Reviews in Clinical Laboratory Sciences, 2002
CD44 is a multistructural and multifunctional cell surface molecule involved in cell proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines, chemokines, and growth factors to the corresponding receptors, and docking of proteases at the cell membrane, as well as in signaling for cell survival.
David, Naor   +4 more
openaire   +2 more sources

Cd44 in colon cancer

European Journal of Cancer, 1995
Alternative splicing of ten different variant exons (v1-v10) is responsible for the creation of a large number of different CD44 surface proteins. Some of these proteins play decisive roles in the metastatic spread of rat tumours. Also in human cancers, CD44 splice variants are frequently expressed in advanced states of tumorigenesis.
Herrlich, P., Pals, S. T., Ponta, H.
openaire   +2 more sources

CD44 structure and function

Frontiers in Bioscience, 1998
In this review we discuss the structural elements of CD44 that have been shown to be involved in specific functions. To this end, we focus primarily on experiments in which CD44 constructs are transfected into cells whose function is then assayed. The hyaluronan binding function of CD44 has been assayed in cell lines and in fusion proteins, termed CD44-
J, Lesley, R, Hyman
openaire   +2 more sources

CD44 in hematological neoplasias

Annals of Hematology, 2011
The CD44 protein family spans a large group of transmembrane glycoproteins acquired by alternative splicing and post-translational modifications. The great heterogeneity in molecular structure is reflected in its various important functions: CD44 mediates (1) interaction between cell and extracellular matrix, (2) signal submission, e.g., by acting as ...
Magdalena Katharina, Hertweck   +2 more
openaire   +2 more sources

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