Results 251 to 260 of about 229,337 (378)

The CD44-HA axis and inflammation in atherosclerosis: A temporal perspective

, 2018
Mia Krolikoski, James Monslow, Ellen Puré   +2 more
openalex   +2 more sources

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

Effects of a Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin on Pancreas in Obese Diabetic Mice. [PDF]

In Vivo
Sekikawa R, Uehara H, Uno K, Sasase T, Nakata Y, Mori Y, Shinohara M, Sugimoto M, Ohta T.   +8 more
europepmc   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin. [PDF]

J Cancer Res Clin Oncol
Xi SY, Zhang H, Wang QJ, Liu YJ, Chang SC, Shi CF, Fang D, Tao LH, Cheng HB, Zou X.   +9 more
europepmc   +1 more source

Histologic profile and CD44 expression in breast cancer tissue of balur nano divine kretek volunteers

, 2016
Dody Novrial, A’liyatur Rosyidah, Saraswati Saraswati, Subagjo Subagjo, Sarjadi Sarjadi   +4 more
openalex   +2 more sources

Diagnostic Roles of Immunohistochemical Markers, CK20, CD44, AMACR, and p53 in Urothelial Carcinoma In Situ: A Meta-Analysis and Diagnostic Test Accuracy Review

, 2023
Dae Seon Yoo, Kyueng‐Whan Min, Jung‐Soo Pyo, Nae Yu Kim   +3 more
openalex   +2 more sources

Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD) [PDF]

Journal of Biological Chemistry, 2012
Karl E. Miletti-González, Kyle Murphy, Muthu N. Kumaran, Abhilash K. Ravindranath, Roman P. Wernyj, Swayamjot Kaur, Gregory D. Miles, Elaine Lim, Rigel Chan, Marina Chekmareva, Debra S. Heller, David Foran, Wenjin Chen, Michael Reiss, Elisa V. Bandera, Kathleen Scotto, Lorna Rodríguez-Rodríguez   +16 more
openaire   +1 more source

The CD44‐Mediated Uptake of Hyaluronic Acid‐Based Carriers in Macrophages

Advanced Healthcare Materials, 2017
Julio M. Rios De La Rosa, A. Tirella, A. Gennari, I. Stratford, N. Tirelli   +4 more
semanticscholar   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source