Results 281 to 290 of about 141,166 (348)

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

The imbalance of Th17/Treg cells exists in asymptomatic hyperuricemia (the early stage of gout). [PDF]

Clin Rheumatol
Zhang LQ, Zhao LJ, Qin AL, Wen QY, Gao C, Li XF.   +5 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Risk stratification for CMV reactivation in sepsis patients: development of an interpretable machine learning model. [PDF]

BMC Infect Dis
Shen C, Chen Y, Pan T, Qu H, Zhang L, Tian R, Wu T, Tan R.   +7 more
europepmc   +1 more source

Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma : interim results and correlations with CD4+ T-lymphocyte counts

, 2018
Daniela A. Bota, Jinah Chung, Manisha Dandekar, Jose Carrillo, Xiao Tang Kong, Beverly Fu, Frank P. K. Hsu, Axel H. Schönthal, Florence M. Hofman, Thomas C. Chen, Raphael Zidovetzki, Chrystel Pretto, Ankie Strik, Virgil E.J.C. Schijns, Apostolos Stathopoulos   +14 more
openalex   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Evaluation of circulating lymphocyte subsets in children with attention-deficit hyperactivity disorder. [PDF]

Transl Pediatr
Zeng J, Yu Y, Ye W, Peng H, Chen D, Chen W, Zhang P.   +6 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Characteristics of peripheral blood lymphocyte subsets in elderly patients with psoriasis. [PDF]

Immun Ageing
Liu R, Zhao J, Gao Q, Kuang Y.
europepmc   +1 more source

Repeated administration of cannabidiol decreases splenic lymphocyte subset numbers in rats. [PDF]

Int J Immunopathol Pharmacol
Turkki TH, Jankowski MM, Glac W, Badtke P, Saito VM, Swiergiel AH, Ignatowska-Jankowska BM.   +6 more
europepmc   +1 more source