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A PDMS-based disposable microfluidic sensor for CD4+ lymphocyte counting
Biomedical Microdevices, 2008A refined sensor for CD4+ lymphocyte count was developed and evaluated by comparison to flow cytometry. The micropillar structured sensor surface was cast in PDMS polymer and surface modified to gain biocompatibility and CD4-cell capturing properties. The sensor works by pure capillary action and sample filling and rinsing is performed without external
Javier Sanchez +4 more
openaire +3 more sources
An integrated microfluidic system for counting of CD4+/CD8+ T lymphocytes
Microfluidics and Nanofluidics, 2010This study reports on an integrated microfluidic system capable of counting CD4+/CD8+ T lymphocytes from a whole blood sample, which may be further applied for the rapid screening of the human immunodeficiency virus (HIV) infection. This system is composed of a sample incubation module for fluorescence-labeling of the target cells and a micro ...
Chun Che Lin +4 more
openaire +2 more sources
Archives of Internal Medicine, 1992
BACKGROUND As many as half of patients infected with the human immunodeficiency virus who are medically eligible for Pneumocystis prophylaxis and zidovudine treatment have not received these treatments. We used the CD4 lymphocyte count as an indicator of
M. Katz +3 more
semanticscholar +1 more source
BACKGROUND As many as half of patients infected with the human immunodeficiency virus who are medically eligible for Pneumocystis prophylaxis and zidovudine treatment have not received these treatments. We used the CD4 lymphocyte count as an indicator of
M. Katz +3 more
semanticscholar +1 more source
Protracted cutaneous disorders in association with low CD4+ lymphocyte counts
British Journal of Dermatology, 1995We report two patients with skin disorders usually associated with severe immunosuppression, who had low CD4+ lymphocyte counts but normal immunoglobulin levels. The patients were HIV negative, and had CD4+ lymphocyte counts just above 300/mm3, but they presented with cutaneous manifestations of profound immunodeficiency.
Ronald Marks, H. A. Kurwa
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AIDS, 2004
Although the depletion of CD4 T cells remains the most reliable marker for estimating the degree of immunosuppression in HIV-1-infected individuals several authors have investigated the possible prognostic and predictive role offered by total lymphocyte count (TLC) as a surrogate of the CD4 cell count in resource-limited settings (RLS).
Elisabeth Coehlo +9 more
openaire +2 more sources
Although the depletion of CD4 T cells remains the most reliable marker for estimating the degree of immunosuppression in HIV-1-infected individuals several authors have investigated the possible prognostic and predictive role offered by total lymphocyte count (TLC) as a surrogate of the CD4 cell count in resource-limited settings (RLS).
Elisabeth Coehlo +9 more
openaire +2 more sources
Predictive value of repeated measurements of CD4 lymphocyte counts on progression to AIDS
AIDS, 1992Description of the relationship between repeated measurements of CD4 lymphocyte count and development of AIDS in asymptomatic HIV-infected patients.Repeated measurements of CD4 lymphocyte counts over an AIDS-free period in asymptomatic HIV-infected patients, and follow-up of the cohort to record subsequent clinical progression to AIDS.The cohort was ...
Florent Boutitie, Stuart J. Pocock
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CD4 T‐lymphocyte counts and Pneumocystis carinii pneumonia in pediatric HIV infection
International Journal of Gynecology & Obstetrics, 1991The relationship between CD4 T-lymphocyte counts and infection with the human immunodeficiency virus (HIV) is retrospectively investigated for 266 HIV-infected and uninfected children who were born to infected women, including 39 with Pneumocystis carinii pneumonia (PCP), in a population-based surveillance study. Of 21 perinatally HIV-infected children
Toni Frederick +5 more
openaire +4 more sources
Predicting CD4 lymphocyte count <200 cells/mm(3) in an HIV type 1-infected African population.
AIDS Research and Human Retroviruses, 2007Clinical criteria are recommended to select HIV-infected patients for initiation of antiretroviral therapy when CD4 lymphocyte testing is unavailable.
S. Morpeth +13 more
semanticscholar +1 more source
AIDS Research and Human Retroviruses, 2001
To explore the role of antibody-dependent cellular cytotoxicity (ADCC) in controlling HIV-1 infection, ADCC was compared with plasma RNA and CD4+ cell count in 40 patients not receiving antiretroviral therapy and in seven patients after the initiation of
D. Forthal, G. Landucci, Bobi Keenan
semanticscholar +1 more source
To explore the role of antibody-dependent cellular cytotoxicity (ADCC) in controlling HIV-1 infection, ADCC was compared with plasma RNA and CD4+ cell count in 40 patients not receiving antiretroviral therapy and in seven patients after the initiation of
D. Forthal, G. Landucci, Bobi Keenan
semanticscholar +1 more source
Journal of Infectious Diseases, 1999
The association between CD4 cell count and duration of virus load suppression was investigated in 558 patients in the Frankfurt HIV Clinic Cohort who had begun highly active antiretroviral therapy and who had virus load declines to
V. Miller +9 more
semanticscholar +1 more source
The association between CD4 cell count and duration of virus load suppression was investigated in 558 patients in the Frankfurt HIV Clinic Cohort who had begun highly active antiretroviral therapy and who had virus load declines to
V. Miller +9 more
semanticscholar +1 more source