Results 211 to 220 of about 34,015 (256)
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Trafficking and function of the tetraspanin CD63
Experimental Cell Research, 2009Tetraspanins comprise a large superfamily of cell surface-associated membrane proteins characterized by four transmembrane domains. They participate in a variety of cellular processes, like cell activation, adhesion, differentiation and tumour invasion. At the cell surface, tetraspanins form networks with a wide diversity of proteins called tetraspanin-
Judith Klumperman
exaly +6 more sources
Generation of cd63-deficient zebrafish to analyze the role of cd63 in viral infection
Fish & Shellfish Immunology, 2021The tetraspanin superfamily proteins are transmembrane proteins identified in a diverse range of eukaryotic organisms. Tetraspanins are involved in a variety of essential biological functions, including cell differentiation, adhesion, migration, signal transduction, intracellular trafficking, and immune responses.
Sumi Jung +5 more
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Expression and localization of CD63 in the intracellular vesicles of odontoblasts
Histochemistry and Cell Biology, 2022We hypothesized that odontoblasts release exosomes as well as dental pulp cells and focused on the exosome membrane marker CD63. Odontoblasts are well-differentiated mesenchymal cells that produce dentin. Dental pulp, a tissue complex formed with odontoblasts, releases exosomes to epithelial cells and stimulates their differentiation to ameloblasts ...
Miwako Matsuki-Fukushima +3 more
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Immunogenicity of CD63 in a patient with melanoma
Melanoma Research, 1997CD63 is a member of the tetraspan family of molecules that is expressed in melanoma and which appears to be involved in regulation of motility and adhesion of melanoma cells. In the present study we have screened a cDNA library from a melanoma cell with antisera from a patient with melanoma and have shown that one of the antigens identified was CD63 ...
Smith, Melanie +3 more
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Biochemical and immunohistochemical characteristics of CD62 and CD63 monoclonal antibodies
Virchows Archiv B Cell Pathology Including Molecular Pathology, 1992During platelet secretion granule membrane glycoproteins are translocated to the plasma membrane. We report here the biochemical and immunohistochemical characterization of a panel of platelet-secretion-specific, CD62 and CD63 monoclonal antibodies (MoAb), which we raised to thrombin-activated platelets.
M J, Metzelaar +4 more
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CD82, and CD63 in thyroid cancer.
International Journal of Molecular Medicine, 2004CD82 (KAI1) and CD63 (ME491) are highly glycosylated proteins which belong to the transmembrane 4 superfamily (TM4SF). CD82 has been implicated as a possible prostate cancer metastasis suppressor gene, whereas CD63 is involved in the progression of human melanoma cancer.
Zhouxun, Chen +12 more
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CD63 positions CD62P for rolling
Blood, 2011Doyle and colleagues identify the tetraspanin CD63 as an essential co-factor for endothelial P-selectin function.[1][1] In the absence of CD63 (by knockout in mice or knockdown in cultured endothelial cells), P-selectin (also known as CD62P) cannot mediate leukocyte tethering and rolling ...
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The tetraspanin CD63 is involved in granule targeting of neutrophil elastase
Blood, 2008Abstract Targeting mechanisms of neutrophil elastase (NE) and other luminal proteins stored in myeloperoxidase (MPO)–positive secretory lysosomes/primary granules of neutrophils are unknown. These granules contain an integral membrane protein, CD63, with an adaptor protein-3–dependent granule delivery system.
Linda, Källquist +6 more
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