Results 1 to 10 of about 215,428 (267)

Investigating the consistency of extracellular vesicle production from breast cancer subtypes using CELLine adherent bioreactors

Journal of Extracellular Biology, 2022
Extracellular vesicle (EV) research has grown rapidly in recent years, largely due to the potential use of EVs as liquid biopsy biomarkers or therapeutics.
Colin L. Hisey, Anastasiia Artuyants, George Guo, Vanessa Chang, Gabrielle Reshef, Martin Middleditch, Bincy Jacob, Lawrence W. Chamley, Cherie Blenkiron   +8 more
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Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

Frontiers in Cell and Developmental Biology, 2020
Extracellular vesicles (EV), structures surrounded by a biological membrane, transport biologically active molecules, and represent a recently identified way of intercellular communication.
Ádám Oszvald, Zsuzsanna Szvicsek, Márton Pápai, Andrea Kelemen, Zoltán Varga, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Edit I. Buzás, Edit I. Buzás, Zoltán Wiener   +11 more
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Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung

Extracellular Vesicle, 2022
Respiratory diseases are among the leading causes of morbidity and mortality worldwide, coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Kristen D. Popowski, Blanca López de Juan Abad, Arianna George, Dylan Silkstone, Elizabeth Belcher, Jaewook Chung, Asma Ghodsi, Halle Lutz, Jada Davenport, Mallory Flanagan, Jorge Piedrahita, Phuong-Uyen C. Dinh, Ke Cheng   +12 more
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Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma

Extracellular Vesicle, 2022
Dysregulated Myc signaling is a key oncogenic pathway in glioblastoma multiforme (GBM). Yet, effective therapeutic targeting of Myc continues to be challenging.
Amanda R. Haltom, Wafa E. Hassen, Janine Hensel, Jiha Kim, Hikaru Sugimoto, Bingrui Li, Kathleen M. McAndrews, Meagan R. Conner, Michelle L. Kirtley, Xin Luo, Bingqing Xie, Olga V. Volpert, Susan Olalekan, Natalia Maltsev, Anindita Basu, Valerie S. LeBleu, Raghu Kalluri   +16 more
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Expanding the horizon of EV-RNAs: LncRNAs in EVs as biomarkers for disease pathways

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are membrane-bound nanoparticles with different types of cargo released by cells and postulated to mediate functions such as intercellular communications. Recent studies have shown that long non-coding RNAs (lncRNAs) or their
Michail Spanos, Priyanka Gokulnath, Emeli Chatterjee, Guoping Li, Dimitrios Varrias, Saumya Das   +5 more
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Guidelines for clinical translation and commercialization of extracellular vesicles and exosomes based therapeutics

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are lipid-bilayer delimited membrane structures released by cells, and play a role in intercell communication and disease development. The Global market for EVs in diagnostic and therapeutic applications is expanding.
Ke Cheng, Raghu Kalluri
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Greasing wheels of cell-free therapies for cardiovascular diseases: Integrated devices of exosomes/exosome-like nanovectors with bioinspired materials

Extracellular Vesicle, 2022
Mortality and morbidity of cardiovascular diseases (CVDs) including ischemic heart disease (IHD) and heart failure (HF) are arising worldwide. Once cardiomyocyte is impaired, it is challenging to regenerate which is largely limited by the irreversibility
Xuerui Chen, Liyun Zhu, Jianyun Liu, Yi Lu, Longlu Pan, Junjie Xiao   +5 more
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The interactions between extracellular vesicles and mesenchymal stem cells: Their potential roles in osteoarthritis development and cartilage repair

Extracellular Vesicle, 2022
Osteoarthritis (OA) is a chronic cartilage degeneration disease affecting total joint and with a wide global impact. Stem cell therapy has emerged as a potential stock for the treatment of OA.
Qiong Yang, Danyang Yue, Qian Ren, Guoqing Xia, Baihui Zhang, Yinyin Qin, Tianfei Ran, Min Wang, Li Pei, Jun Pan   +9 more
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PD-L1 antibodies-armed exosomal vaccine for enhanced cancer immunotherapy by simultaneously in situ activating T cells and blocking PD-1/PD-L1 axis

Extracellular Vesicle, 2022
Tumor immunotherapy significantly rewards antigen-specific T-cell responses, which have been recognized as the foundation of adaptive immune responses.
Xinyue Dai, Zhaoshuo Wang, Miao Fan, Huifang Liu, Xinjian Yang, Xueyi Wang, Xiaohan Zhou, Yunlu Dai, Jinchao Zhang, Zhenhua Li   +9 more
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Complex RNA world in small extracellular vesicles for liquid biopsy in cancer management

Extracellular Vesicle, 2022
Liquid biopsy is a valuable tool in oncology with its advantages of non-invasiveness, longitudinal sampling, and capturing the intra- and inter-tumor heterogeneity. Small extracellular vesicles (sEVs) are released by cells into various biological fluids,
Shuhong Wang, Yusheng Lin, Yishi Zhang, Xiaofu Qiu, Yunlong Pan, Sai-Ching Jim Yeung, Hao Zhang   +6 more
doaj   +1 more source