Results 1 to 10 of about 987,123 (118)

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

Cell, 2020
SUMMARY There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in 426 human samples from tissue explants (TEs), plasma, and ...
Charles Rudin, Maša Alečković, Mina Bissell   +2 more
exaly   +2 more sources

Standardization of Sample Collection, Isolation and Analysis Methods in Extracellular Vesicle Research

Journal of Extracellular Vesicles, 2013
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles (EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease and therapeutic targets.
Clotilde Théry, Jan Lötvall, Lynne T. Bemis   +2 more
exaly   +2 more sources

Investigating the consistency of extracellular vesicle production from breast cancer subtypes using CELLine adherent bioreactors

Journal of Extracellular Biology, 2022
Extracellular vesicle (EV) research has grown rapidly in recent years, largely due to the potential use of EVs as liquid biopsy biomarkers or therapeutics.
Colin L. Hisey, Anastasiia Artuyants, George Guo, Vanessa Chang, Gabrielle Reshef, Martin Middleditch, Bincy Jacob, Lawrence W. Chamley, Cherie Blenkiron   +8 more
doaj   +1 more source

Context-specific regulation of extracellular vesicle biogenesis and cargo selection

Nature reviews. Molecular cell biology, 2023
Extracellular vesicles (EVs) have emerged as important players in intercellular communication, carrying proteins, lipids, nucleic acids and various signalling molecules between cells.
Andrew C. Dixson, T. Dawson, D. Di Vizio, Alissa M. Weaver   +3 more
semanticscholar   +1 more source

A compendium of single extracellular vesicle flow cytometry

Journal of Extracellular Vesicles, 2023
Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells, which are larger than EVs.
Joshua A. Welsh, G. Arkesteijn, Michel Bremer, Michael Cimorelli, F. Dignat-George, B. Giebel, Andre Görgens, A. Hendrix, Martine Kuiper, R. Lacroix, J. Lannigan, T. V. van Leeuwen, E. Lozano-Andrés, S. Rao, S. Robert, L. de Rond, Vera A. Tang, T. Tertel, Xiao-Mei Yan, M. Wauben, J. Nolan, Jennifer C. Jones, R. Nieuwland, E. van der Pol   +23 more
semanticscholar   +1 more source

MicroRNA sequence codes for small extracellular vesicle release and cellular retention

Nature, 2021
Exosomes and other small extracellular vesicles (sEVs) provide a unique mode of cell-to-cell communication in which microRNAs (miRNAs) produced and released from one cell are taken up by cells at a distance where they can enact changes in gene ...
Rubén García-Martín, Guo-Xiao Wang, B. Brandao, Tamires M. Zanotto, Samah Shah, S. Patel, B. Schilling, C. Kahn   +7 more
semanticscholar   +1 more source

MIBlood‐EV: Minimal information to enhance the quality and reproducibility of blood extracellular vesicle research

Journal of Extracellular Vesicles, 2023
Blood is the most commonly used body fluid for extracellular vesicle (EV) research. The composition of a blood sample and its derivatives (i.e., plasma and serum) are not only donor‐dependent but also influenced by collection and preparation protocols ...
F. Lucien, Dakota Gustafson, M. Lenassi, Bo Li, J. Teske, É. Boilard, Katharina Clemm von Hohenberg, J. Falcón-Perez, A. Gualerzi, A. Reale, Jennifer C. Jones, C. Lässer, Charlotte Lawson, Irina Nazarenko, L. O'Driscoll, Ryan Pink, P. Siljander, Carolina Soekmadji, An Hendrix, Joshua A. Welsh, K. Witwer, R. Nieuwland   +21 more
semanticscholar   +1 more source

Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Materials Today Bio, 2022
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles secreted by cells that play important biological roles. Mesenchymal stem cells are a class of cells with the potential for self-healing and multidirectional ...
Yikun Ju, Yue Hu, Pu Yang, Xiaoyan Xie, B. Fang   +4 more
semanticscholar   +1 more source

Neuronally Derived Extracellular Vesicle α-Synuclein as a Serum Biomarker for Individuals at Risk of Developing Parkinson Disease

JAMA Neurology, 2023
This study investigate whether α-synuclein in neuronally derived serum-extracellular vesicles identifies individuals at risk of developing Parkinson disease and related dementia.
Shi-Jun Yan, Cheng Jiang, A. Janzen, T. Barber, A. Seger, M. Sommerauer, Jason J. Davis, Kenneth Marek, Michele T. Hu, W. Oertel, G. Tofaris   +10 more
semanticscholar   +1 more source

Migrasome: a new functional extracellular vesicle

Cell Death Discovery, 2023
Migrasome is a novel cellular organelle produced during cell migration, and its biogenesis depends on the migration process. It is generated in a variety of cells such as immune cells, metastatic tumor cells, other special functional cells like podocytes
Xi-De Zhang, Liuhuan Yao, Yuan-Yuan Meng, Bai-Long Li, Yan-Yong Yang, Fu Gao   +5 more
semanticscholar   +1 more source