Results 21 to 30 of about 1,588,316 (303)

Extracellular vesicle-Based Interorgan Transport of Mitochondria from Energetically Stressed Adipocytes

open access: yesCell Metabolism, 2021
Summary: Adipocytes undergo intense energetic stress in obesity resulting in loss of mitochondrial mass and function. We have found that adipocytes respond to mitochondrial stress by rapidly and robustly releasing small extracellular vesicles (sEVs ...
C. Crewe   +15 more
semanticscholar   +1 more source

Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

open access: yesFrontiers in Cell and Developmental Biology, 2020
Extracellular vesicles (EV), structures surrounded by a biological membrane, transport biologically active molecules, and represent a recently identified way of intercellular communication.
Ádám Oszvald   +11 more
doaj   +1 more source

Single Extracellular VEsicle Nanoscopy

open access: yesJournal of Extracellular Vesicles, 2023
Extracellular vesicles (EVs) and their cargo constitute novel biomarkers. EV subpopulations have been defined not only by abundant tetraspanins (e.g., CD9, CD63 and CD81) but also by specific markers derived from their source cells. However, it remains a
A. Saftics   +10 more
semanticscholar   +1 more source

Extracellular Vesicles in Transplantation [PDF]

open access: yesFrontiers in Immunology, 2022
Extracellular vesicles (EVs) have been extensively studied in the last two decades. It is now well documented that they can actively participate in the activation or regulation of immune system functions through different mechanisms, the most studied of which include protein–protein interactions and miRNA transfers.
Nicolas Sailliet   +7 more
openaire   +5 more sources

Extracellular vesicle-matrix interactions

open access: yesNature Reviews Materials, 2023
The extracellular matrix (ECM) harbours various signals to control cellular functions and the materiality of tissues. Most efforts to synthetically reconstitute the matrix by biomaterial design have focused on decoupling cell-secreted and polymer-based ...
Koushik Debnath   +4 more
semanticscholar   +1 more source

The cancer cell-derived extracellular vesicle glycocode in immunoevasion

open access: yes, 2022
Recent evidence suggests that cancer cell-derived extracellular vesicles might facilitate immunoevasion. Glycans are known to play a key role in immunomodulation, especially when tethered to biological membranes.
Goncalves, JP   +4 more
core   +1 more source

Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung

open access: yesExtracellular Vesicle, 2022
Respiratory diseases are among the leading causes of morbidity and mortality worldwide, coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Kristen D. Popowski   +12 more
doaj   +1 more source

Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process

open access: yesCommunications Biology, 2023
Extracellular vesicles (EVs) are thought to mediate intercellular communication by transferring cargoes from donor to acceptor cells. The EV content-delivery process within acceptor cells is still poorly characterized and debated.
Maria-Laura Tognoli   +8 more
semanticscholar   +1 more source

Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma

open access: yesExtracellular Vesicle, 2022
Dysregulated Myc signaling is a key oncogenic pathway in glioblastoma multiforme (GBM). Yet, effective therapeutic targeting of Myc continues to be challenging.
Amanda R. Haltom   +16 more
doaj   +1 more source

Advances in extracellular vesicle isolation methods: a path towards cell-type specific EV isolation

open access: yesExtracellular Vesicles and Circulating Nucleic Acids, 2023
Extracellular vesicles are small, heterogenous, phospholipid-rich vesicles that are secreted by all cells into the extracellular space. They play a key role in intercellular communication because they can transport a variety of biomolecules such as ...
Adnan Shami-Shah   +2 more
semanticscholar   +1 more source

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