Results 21 to 30 of about 215,428 (267)

Sucrose-based cryoprotective storage of extracellular vesicles

Extracellular Vesicle, 2022
Advancements in extracellular vesicle (EV) studies necessitate the development of optimized storage conditions to ensure preservation of physical and biochemical characteristics.
Sierra A. Walker, Irina Davidovich, Yubo Yang, Andrew Lai, Jenifer Pendiuk Goncalves, Vatsal Deliwala, Sara Busatto, Shane Shapiro, Na’ama Koifman, Carlos Salomon, Yeshayahu Talmon, Joy Wolfram   +11 more
doaj   +1 more source

Extracellular Vesicles of Neutrophils [PDF]

Immune Network, 2018
Extracellular vesicles (EVs) are membrane-derived vesicles that mediate intercellular communications. As professional phagocytes, neutrophils also produce EVs in response to various inflammatory stimuli during inflammatory processes. Neutrophil-derived EVs can be categorized into 2 subtypes according to the mechanism of generation.
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Extracellular Vesicles in Human Milk [PDF]

Pharmaceuticals, 2021
Milk supports the growth and development of infants. An increasing number of mostly recent studies have demonstrated that milk contains a hitherto undescribed component called extracellular vesicles (EVs). This presents questions regarding why milk contains EVs and what their function is. Recently, we showed that EVs in human milk expose tissue factor,
Yong Hu, Johannes Thaler, Rienk Nieuwland   +2 more
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Extracellular RNA in oncogenesis, metastasis and drug resistance

RNA Biology
Extracellular vesicles and nanoparticles (EVPs) are now recognized as a novel form of cell–cell communication. All cells release a wide array of heterogeneous EVPs with distinct protein, lipid, and RNA content, dependent on the pathophysiological state ...
Hannah Nelson, Sherman Qu, Jeffrey L. Franklin, Qi Liu, Heather H. Pua, Kasey C. Vickers, Alissa M. Weaver, Robert J. Coffey, James G. Patton   +8 more
doaj   +1 more source

Extracellular Vesicles as Regulators of the Extracellular Matrix

Bioengineering, 2023
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication. As EVs are released and move from parent to recipient cell, EVs interact with the extracellular matrix (ECM) which ...
Neil J. Patel, Anisa Ashraf, Eun Ji Chung   +2 more
openaire   +3 more sources

Extracellular Vesicles in Angiogenesis

Circulation Research, 2017
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies, microvesicles, and exosomes, have emerged as important players in cell-to-cell communication in normal physiology and pathological conditions. EVs encapsulate and convey various bioactive molecules that are further transmitted to neighboring or more distant cells ...
Todorova, Dilyana, Simoncini, Stéphanie, Lacroix, Romaric, Sabatier, Florence, Dignat-George, Françoise   +4 more
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Extracellular Vesicles in Phytopathogenic Fungi

Extracellular Vesicles and Circulating Nucleic Acids, 2023
Extracellular vesicles (EVs) are nano-sized, lipid compartments that mediate the intercellular transport of lipids, proteins, nucleic acids and metabolites. During infectious diseases, EVs released by host cells promote immune responses, while those released by pathogens attempt to subvert host immunity.
Rutter, Brian D., Innes, Roger W.
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Exomap1 mouse: A transgenic model for in vivo studies of exosome biology

Extracellular Vesicle, 2023
Exosomes are small extracellular vesicles (sEVs) of ∼30–150 nm in diameter that are enriched in exosome marker proteins and play important roles in health and disease.
Francis K. Fordjour, Sarah Abuelreich, Xiaoman Hong, Emeli Chatterjee, Valeria Lallai, Martin Ng, Andras Saftics, Fengyan Deng, Natacha Carnel-Amar, Hiroaki Wakimoto, Kazuhide Shimizu, Malia Bautista, Tuan Anh Phu, Ngan K. Vu, Paige C. Geiger, Robert L. Raffai, Christie D. Fowler, Saumya Das, Lane K. Christenson, Tijana Jovanovic-Talisman, Stephen J. Gould   +20 more
doaj   +1 more source

Immunogenicity of Extracellular Vesicles

Advanced Materials
AbstractExtracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery systems due to demonstrated safety and efficacy in preclinical models and early‐stage clinical trials. There is an urgent need to address the immunogenicity of EVs (beyond the apparent lack of immunotoxicity) to advance clinical development.
Yutian Xia, Jianzhong Zhang, Gang Liu, Joy Wolfram   +3 more
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Extracellular Vesicles as Drug Transporters

International Journal of Molecular Sciences, 2023
Extracellular vesicles (EVs) are lipid bilayer-delimited particles. According to their size and synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and apoptotic bodies. Extracellular vesicles are of great interest to the scientific community due to their role in cell-to-cell communication and their drug-carrying ...
Monika Nowak, Julia Górczyńska, Katarzyna Kołodzińska, Jakub Rubin, Anna Choromańska   +4 more
openaire   +3 more sources